PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thecc1EG000070t1

Common Name

TCM_000070

Organism

Theobroma cacao

Taxonomic ID

3641

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma

Family

Nin-like

Protein Properties

Length: 945aa MW: 105045 Da PI: 6.2889

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thecc1EG000070t1	genome	CGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	83.3	2.3e-26	808	857	3	52
RWP-RK 3 keisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 ++i ledl+kyF+lpi +A+++L+v+lTvLKr+CR++GI+RWPhRkiksl Thecc1EG000070t1 808 ARIALEDLAKYFDLPIVEASRNLNVGLTVLKRKCREFGIPRWPHRKIKSL 857 689*********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.50.50.60	5.4E-30	11	55	IPR023753	FAD/NAD(P)-binding domain
SuperFamily	SSF51905	2.09E-40	12	363	IPR023753	FAD/NAD(P)-binding domain
Pfam	PF00996	3.4E-8	14	63	IPR018203	GDP dissociation inhibitor
PRINTS	PR00891	2.1E-22	16	34	IPR018203	GDP dissociation inhibitor
PRINTS	PR00891	2.1E-22	34	51	IPR018203	GDP dissociation inhibitor
Gene3D	G3DSA:3.50.50.60	5.4E-30	93	94	IPR023753	FAD/NAD(P)-binding domain
Pfam	PF00996	1.4E-28	95	346	IPR018203	GDP dissociation inhibitor
Gene3D	G3DSA:3.30.519.10	3.7E-27	112	164	No hit	No description
PRINTS	PR00891	2.1E-22	133	149	IPR018203	GDP dissociation inhibitor
Gene3D	G3DSA:1.10.405.10	2.1E-26	166	274	No hit	No description
PRINTS	PR00891	2.1E-22	183	198	IPR018203	GDP dissociation inhibitor
Gene3D	G3DSA:3.50.50.60	5.4E-30	278	385	IPR023753	FAD/NAD(P)-binding domain
PRINTS	PR00891	2.1E-22	285	306	IPR018203	GDP dissociation inhibitor
SuperFamily	SSF54373	9.81E-14	371	465	No hit	No description
Gene3D	G3DSA:3.30.519.10	3.7E-27	386	453	No hit	No description
PROSITE profile	PS51519	20.111	792	877	IPR003035	RWP-RK domain
Pfam	PF02042	1.3E-21	810	857	IPR003035	RWP-RK domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0007264	Biological Process	small GTPase mediated signal transduction
GO:0050790	Biological Process	regulation of catalytic activity
GO:0055114	Biological Process	oxidation-reduction process
GO:2000541	Biological Process	positive regulation of protein geranylgeranylation
GO:0005829	Cellular Component	cytosol
GO:0005092	Molecular Function	GDP-dissociation inhibitor activity
GO:0016491	Molecular Function	oxidoreductase activity
GO:0017137	Molecular Function	Rab GTPase binding

Sequence ? help Back to Top
Protein Sequence Length: 945 aa Download sequence Send to blast
MNDLPPYPPI DPTTFDLIVI GTGLPESIVA AAASTASKSV LHLDPNPFYG SHFSSIPLTD 60 LSSFLSFHST SPSPSPSPSS NGHHDFTALD FAIRPLYSSL DISNFSPQLL DQHSRRFNID 120 VAGPRVLFCA DKSIDLMLKS GASQYMEFKS IDASFVGDDK GNLWSVPDSR AAIFKDKSLG 180 LMEKNQLMRF FKLVQGHLAG EEGLKISEED LESPFVDFLN KMGLPPKIKS FILYAIAMAD 240 YDQEDVGVCQ DLLKTKDGID QLALYNASVG RFSNALGALI YPVYGQGELS QAFCRRAAVK 300 GCLYVLRMPV TSLLVDKDSG CYKGVRLASG QDIFSKKLIL DPSFTVPLPL GSPSPHPLQE 360 KLPLFSLRDD RGKVARGICI TKTSLKPDVS NFLVVYPPRS LFPEQVTSIR LLQMGSNLAV 420 CPPDMFVIYI SALCTDDDQG KKLLHAVMNT LVTLPVSTNS ESNAAVQSES AESGGAAQNE 480 TAESSFTVQS DLGEGKPTLL WSALYIQKLT LGQVDFICSG PMPDGKLNYN DLLDATVKLF 540 QEIYPDEEFF PETSTLEFSE DDVQFLTCHA TLQTCGQGPK VVGEQSWFAA FLLTLMISSS 600 SSSSSWSCLK TPSLTTLLVF ENTNNKELIR SLHVYRLENG EENEVEREFV FRKDGPYVEM 660 ATSPFLRLQG FRPQELFEGR VTGLWLCVFA FHAHRLPRFF FIPSLLSISR NPKLKSIPTL 720 ANDLQVIFQR CCGTEDRGPS RKSSKETCTR DGDNYCQLKR SLLVLDQDLN CLPNSIATSE 780 LLKSQHTEQS ATGVAVKKKK RADSKDIARI ALEDLAKYFD LPIVEASRNL NVGLTVLKRK 840 CREFGIPRWP HRKIKSLDGL IRDLQEEAEQ RQQEDEAAAF AVAKRRMMLE TEKESIEREP 900 FIELKSETKR FRQDIFKRRH KAKALKNQCL SVLHNPVTEL DGNT*

Sequence ? help Back to Top

Protein Sequence Length: 945 aa Download sequence Send to blast

MNDLPPYPPI DPTTFDLIVI GTGLPESIVA AAASTASKSV LHLDPNPFYG SHFSSIPLTD  60
LSSFLSFHST SPSPSPSPSS NGHHDFTALD FAIRPLYSSL DISNFSPQLL DQHSRRFNID  120
VAGPRVLFCA DKSIDLMLKS GASQYMEFKS IDASFVGDDK GNLWSVPDSR AAIFKDKSLG  180
LMEKNQLMRF FKLVQGHLAG EEGLKISEED LESPFVDFLN KMGLPPKIKS FILYAIAMAD  240
YDQEDVGVCQ DLLKTKDGID QLALYNASVG RFSNALGALI YPVYGQGELS QAFCRRAAVK  300
GCLYVLRMPV TSLLVDKDSG CYKGVRLASG QDIFSKKLIL DPSFTVPLPL GSPSPHPLQE  360
KLPLFSLRDD RGKVARGICI TKTSLKPDVS NFLVVYPPRS LFPEQVTSIR LLQMGSNLAV  420
CPPDMFVIYI SALCTDDDQG KKLLHAVMNT LVTLPVSTNS ESNAAVQSES AESGGAAQNE  480
TAESSFTVQS DLGEGKPTLL WSALYIQKLT LGQVDFICSG PMPDGKLNYN DLLDATVKLF  540
QEIYPDEEFF PETSTLEFSE DDVQFLTCHA TLQTCGQGPK VVGEQSWFAA FLLTLMISSS  600
SSSSSWSCLK TPSLTTLLVF ENTNNKELIR SLHVYRLENG EENEVEREFV FRKDGPYVEM  660
ATSPFLRLQG FRPQELFEGR VTGLWLCVFA FHAHRLPRFF FIPSLLSISR NPKLKSIPTL  720
ANDLQVIFQR CCGTEDRGPS RKSSKETCTR DGDNYCQLKR SLLVLDQDLN CLPNSIATSE  780
LLKSQHTEQS ATGVAVKKKK RADSKDIARI ALEDLAKYFD LPIVEASRNL NVGLTVLKRK  840
CREFGIPRWP HRKIKSLDGL IRDLQEEAEQ RQQEDEAAAF AVAKRRMMLE TEKESIEREP  900
FIELKSETKR FRQDIFKRRH KAKALKNQCL SVLHNPVTEL DGNT*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ltx_R	1e-35	112	551	219	603	Rab Escort Protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component composed of the alpha subunit RGTA and the beta subunit RGTB (Probable). Preferentially binds the GDP-bound form of Rab and stimulates geranylgeranylation of various Rab GTPases in vitro (PubMed:15854662). {ECO:0000269\|PubMed:15854662, ECO:0000305\|PubMed:15854662, ECO:0000305\|PubMed:17140818}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021275266.1	0.0	LOW QUALITY PROTEIN: rab escort protein 1
Swissprot	Q8LLD4	0.0	REP_ARATH; Rab escort protein 1
TrEMBL	A0A061DF33	0.0	A0A061DF33_THECC; Rab escort protein
STRING	EOX90669	0.0	(Theobroma cacao)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G35590.1	4e-79	RWP-RK domain-containing protein

Link Out ? help Back to Top
Phytozome	Thecc1EG000070t1
Entrez Gene	18610652

Publications ? help Back to Top
Lange BM,Ghassemian M Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism. Plant Mol. Biol., 2003. 51(6): p. 925-48 [PMID:12777052] Hála M,Eliás M,Zárský V A specific feature of the angiosperm Rab escort protein (REP) and evolution of the REP/GDI superfamily. J. Mol. Biol., 2005. 348(5): p. 1299-313 [PMID:15854662] Wojtas M, et al. Cloning and characterization of Rab Escort Protein (REP) from Arabidopsis thaliana. Cell Biol. Int., 2007. 31(3): p. 246-51 [PMID:17140818] Motamayor JC, et al. The genome sequence of the most widely cultivated cacao type and its use to identify candidate genes regulating pod color. Genome Biol., 2013. 14(6): p. r53 [PMID:23731509] Shi W,Zeng Q,Kunkel BN,Running MP Arabidopsis Rab Geranylgeranyltransferases Demonstrate Redundancy and Broad Substrate Specificity in Vitro. J. Biol. Chem., 2016. 291(3): p. 1398-410 [PMID:26589801]