PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Traes_5BL_6617B7367.2

Organism

Triticum aestivum

Taxonomic ID

4565

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum

Family

NAC

Protein Properties

Length: 1029aa MW: 111338 Da PI: 5.49

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Traes_5BL_6617B7367.2	genome	IWGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	27	1.3e-08	21	154	17	126
NAM 17 eyLkkkvegkkleleevikevdiykvePwdLpk..........kvkaeekewyfFskrdkkyatgkrknra..tk....sgyWkatgk 88 + L+ kv+g++++ ++i+e++ y++ P dL + + +++ wyf+s+ + + + g ++r + + +W+ g Traes_5BL_6617B7367.2 21 KLLRLKVAGEPFPH-SFIHELNAYSAAPADLVRgrdpapgtgqAGDGKGMAWYFYSPVNWHDSAGGAPRRNrqVGgggeRRFWHPEGG 107 67999****999.89**********74578888765322335559***999998875555422333333558** PP NAM 89 dkevlskkgelvgl.kktLvfy........kgrapkgektdWvmhey 126 +k++l +++ vg +tL + +++ + ++ W+m e Traes_5BL_6617B7367.2 108 EKPILGPDSKPVGAyWRTLSYVlkinnppgAKKSFRNKRLGWCMVEI 154 *****9999886268999987666665445555667788888775 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51005	14.879	4	176	IPR003441	NAC domain
SuperFamily	SSF101941	7.06E-16	22	176	IPR003441	NAC domain
Gene3D	G3DSA:3.40.1160.10	1.3E-26	280	523	IPR001048	Aspartate/glutamate/uridylate kinase
SuperFamily	SSF53633	2.84E-32	284	520	IPR001048	Aspartate/glutamate/uridylate kinase
Pfam	PF00696	1.2E-5	435	505	IPR001048	Aspartate/glutamate/uridylate kinase
SuperFamily	SSF55021	6.72E-5	611	684	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0016740	Molecular Function	transferase activity

Sequence ? help Back to Top
Protein Sequence Length: 1029 aa Download sequence Send to blast
MLATGELQSL APQLDFLELA KLLRLKVAGE PFPHSFIHEL NAYSAAPADL VRGRDPAPGT 60 GQAGDGKGMA WYFYSPVNWH DSAGGAPRRN RQVGGGGERR FWHPEGGEKP ILGPDSKPVG 120 AYWRTLSYVL KINNPPGAKK SFRNKRLGWC MVEIGLQQQQ DGAAGQQWEL CKVYRSPSPR 180 STADPVETST AAAAGAQGIL PAAGNGVSGA EGRPHDSALE GEAIPEVLGG DMPCPPAPPS 240 ALCDYNVHFP GVNRSPALLI APASIHGTLA IMKKTDAASA AATVVMKLDG SSIPSAERMK 300 EMANLVLGFE SPVVVVSAMG NTASNILLAA WKALSCDLQE ASEIDEFKNI RELHLRTVDE 360 LGLDSSTVSG SLDQLEQHLQ YAAMTKEMTS MTRDCLVSVC EGTSTKMFFE YLNKLGKGAV 420 QEWELHTVAA FGSDGNDLAA AIIGRDLGLE EIQVWKDQDI FTCDTNVCAK AIPVPYLTFD 480 EAAELGFFSA QSIQLATECG ISVRVKNSFN PEAPGTLITK TRDTTKSALS SIALKSNITI 540 LDIQRTGTLD QSAFVEKAIS KFKYFEYLGI SVDWVATSEN MSFTLVPSKP LSQDLIQLAL 600 DNAVKELGKI ATVHQRQDIS AICLIGNPQM SLPILGKVLN VLGSNNFDIE KVPRGSPKVA 660 NVSLVVRDNA AERCVQLLHS VFFELNGCPV PVNSQAAASG SSDKRKADGD HPDAPTGVRR 720 EMAETESLVP EELERSLLSN DETLQLEFQK FLSDDRNYEP SGLLDNVWTH QDDEPPSYVW 780 THQDDELPSY VFQTHQDDEP PSYVFQTQGG PPPRRLRLLY GVPSSHRLQE VLNVPPRTPQ 840 EVGALIRIHR GVRSRMCLAI SFFQNMDYLG ISINWVATSE GKMPLTLVTS ELLSQALIQP 900 ALEEAGKELQ NTPAVHGLYN RSVISLTGNA QLSPSNLRKV LNVLGSSPVV VEKVSQGSSK 960 VAKISLVVHG NVAQHYGEVL RSAFFKNPVD SSAPSSYGVK KNTEDPPSGG FSEAGISKIS 1020 ERVRRLAID

Sequence ? help Back to Top

Protein Sequence Length: 1029 aa Download sequence Send to blast

MLATGELQSL APQLDFLELA KLLRLKVAGE PFPHSFIHEL NAYSAAPADL VRGRDPAPGT  60
GQAGDGKGMA WYFYSPVNWH DSAGGAPRRN RQVGGGGERR FWHPEGGEKP ILGPDSKPVG  120
AYWRTLSYVL KINNPPGAKK SFRNKRLGWC MVEIGLQQQQ DGAAGQQWEL CKVYRSPSPR  180
STADPVETST AAAAGAQGIL PAAGNGVSGA EGRPHDSALE GEAIPEVLGG DMPCPPAPPS  240
ALCDYNVHFP GVNRSPALLI APASIHGTLA IMKKTDAASA AATVVMKLDG SSIPSAERMK  300
EMANLVLGFE SPVVVVSAMG NTASNILLAA WKALSCDLQE ASEIDEFKNI RELHLRTVDE  360
LGLDSSTVSG SLDQLEQHLQ YAAMTKEMTS MTRDCLVSVC EGTSTKMFFE YLNKLGKGAV  420
QEWELHTVAA FGSDGNDLAA AIIGRDLGLE EIQVWKDQDI FTCDTNVCAK AIPVPYLTFD  480
EAAELGFFSA QSIQLATECG ISVRVKNSFN PEAPGTLITK TRDTTKSALS SIALKSNITI  540
LDIQRTGTLD QSAFVEKAIS KFKYFEYLGI SVDWVATSEN MSFTLVPSKP LSQDLIQLAL  600
DNAVKELGKI ATVHQRQDIS AICLIGNPQM SLPILGKVLN VLGSNNFDIE KVPRGSPKVA  660
NVSLVVRDNA AERCVQLLHS VFFELNGCPV PVNSQAAASG SSDKRKADGD HPDAPTGVRR  720
EMAETESLVP EELERSLLSN DETLQLEFQK FLSDDRNYEP SGLLDNVWTH QDDEPPSYVW  780
THQDDELPSY VFQTHQDDEP PSYVFQTQGG PPPRRLRLLY GVPSSHRLQE VLNVPPRTPQ  840
EVGALIRIHR GVRSRMCLAI SFFQNMDYLG ISINWVATSE GKMPLTLVTS ELLSQALIQP  900
ALEEAGKELQ NTPAVHGLYN RSVISLTGNA QLSPSNLRKV LNVLGSSPVV VEKVSQGSSK  960
VAKISLVVHG NVAQHYGEVL RSAFFKNPVD SSAPSSYGVK KNTEDPPSGG FSEAGISKIS  1020
ERVRRLAID

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2cdq_A	1e-114	273	987	14	485	ASPARTOKINASE
2cdq_B	1e-114	273	987	14	485	ASPARTOKINASE
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Functional Description ? help Back to Top
Source	Description
UniProt	Involved in the first step of essential amino acids lysine, threonine, methionine and isoleucine synthesis via the aspartate-family pathway.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020168595.1	1e-175	aspartokinase 1, chloroplastic-like isoform X1
Refseq	XP_020168596.1	1e-175	aspartokinase 1, chloroplastic-like isoform X1
Swissprot	Q9LYU8	1e-113	AK1_ARATH; Aspartokinase 1, chloroplastic
TrEMBL	A0A3B6LX64	0.0	A0A3B6LX64_WHEAT; Uncharacterized protein
STRING	Traes_5BL_6617B7367.2	0.0	(Triticum aestivum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G77450.1	8e-08	NAC domain containing protein 32

Publications ? help Back to Top
Yoshioka Y,Kurei S,Machida Y Identification of a monofunctional aspartate kinase gene of Arabidopsis thaliana with spatially and temporally regulated expression. Genes Genet. Syst., 2001. 76(3): p. 189-98 [PMID:11569502] Mas-Droux C, et al. A novel organization of ACT domains in allosteric enzymes revealed by the crystal structure of Arabidopsis aspartate kinase. Plant Cell, 2006. 18(7): p. 1681-92 [PMID:16731588] Curien G,Laurencin M,Robert-Genthon M,Dumas R Allosteric monofunctional aspartate kinases from Arabidopsis. FEBS J., 2007. 274(1): p. 164-76 [PMID:17140415] Jander G,Joshi V Aspartate-Derived Amino Acid Biosynthesis in Arabidopsis thaliana. Arabidopsis Book, 2009. 7: p. e0121 [PMID:22303247] Brenchley R, et al. Analysis of the bread wheat genome using whole-genome shotgun sequencing. Nature, 2012. 491(7426): p. 705-10 [PMID:23192148] Van Bochaute P,Novoa A,Ballet S,Rognes SE,Angenon G Regulatory mechanisms after short- and long-term perturbed lysine biosynthesis in the aspartate pathway: the need for isogenes in Arabidopsis thaliana. Physiol Plant, 2013. 149(4): p. 449-60 [PMID:23556418] Clark TJ,Lu Y Analysis of Loss-of-Function Mutants in Aspartate Kinase and Homoserine Dehydrogenase Genes Points to Complexity in the Regulation of Aspartate-Derived Amino Acid Contents. Plant Physiol., 2015. 168(4): p. 1512-26 [PMID:26063505] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815] Rognes SE,Lea PJ,Miflin BJ S-adenosylmethionine--a novel regulator of aspartate kinase. Nature, 1980. 287(5780): p. 357-9 [PMID:6252474] Ghislain M,Frankard V,Vandenbossche D,Matthews BF,Jacobs M Molecular analysis of the aspartate kinase-homoserine dehydrogenase gene from Arabidopsis thaliana. Plant Mol. Biol., 1994. 24(6): p. 835-51 [PMID:8204822] Ben-Tzvi Tzchori I,Perl A,Galili G Lysine and threonine metabolism are subject to complex patterns of regulation in Arabidopsis. Plant Mol. Biol., 1996. 32(4): p. 727-34 [PMID:8980524] Frankard V,Vauterin M,Jacobs M Molecular characterization of an Arabidopsis thaliana cDNA coding for a monofunctional aspartate kinase. Plant Mol. Biol., 1997. 34(2): p. 233-42 [PMID:9207839] Tang G,Zhu-Shimoni JX,Amir R,Zchori IB,Galili G Cloning and expression of an Arabidopsis thaliana cDNA encoding a monofunctional aspartate kinase homologous to the lysine-sensitive enzyme of Escherichia coli. Plant Mol. Biol., 1997. 34(2): p. 287-93 [PMID:9207844] Zhu-Shimoni JX,Galili G Expression of an arabidopsis aspartate Kinase/Homoserine dehydrogenase gene is metabolically regulated by photosynthesis-related signals but not by nitrogenous compounds Plant Physiol., 1998. 116(3): p. 1023-8 [PMID:9501134]