PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sevir.1G187500.3.p
Organism
Setaria viridis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria
Family E2F/DP
Protein Properties Length: 372aa    MW: 41717.8 Da    PI: 4.4703
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sevir.1G187500.3.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP85.54.2e-2752117171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+llt+kf++ll+++++gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  Sevir.1G187500.3.p  52 RYDSSLGLLTKKFINLLKQAPDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 117
                         6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.9E-2949119IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.72E-1852115IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.0E-3552117IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.7E-2454117IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146603.84E-50127233No hitNo description
SuperFamilySSF1440746.28E-35129233No hitNo description
PfamPF164211.2E-33132231IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 372 aa     Download sequence    Send to blast
MLVSGNLVND MPWSFALNSS LHMFSWNKRV KMNIFLYAGS PLNPATPAGT CRYDSSLGLL  60
TKKFINLLKQ APDGILDLNN AAETLEVQKR RIYDITNVLE GIGLIEKTLK NRIRWKGLDD  120
SGVDLDNGIS ALQAEVENLS LQEQALDERI SDMREKLRGL TEDENNQRWL YVTEDDIKGL  180
PCFQNETLIA IKAPHGTTLE VPDPDEAGDY LQRRYRIVLR STMGPIDVYL VSQFDEKFEE  240
LGGVETPARH ANMSRHHTVE DFNATNAGQC STSMDVVHNV QQNQRTPQDP NASHDFGGMT  300
RIIPSDVDTD ADYWLLTEGD VSITDMWKTA PEVQWDQMDF LSEEVVTPRA QNQQPVAVGG  360
PHMQVPSMDK P*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-2444118274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSevir.1G187500.3.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004952668.10.0transcription factor E2FA
SwissprotQ9FNY01e-116E2FA_ARATH; Transcription factor E2FA
TrEMBLK3YS640.0K3YS64_SETIT; Uncharacterized protein
STRINGSi017108m0.0(Setaria italica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-120E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]