PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Sevir.1G187500.2.p | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria
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Family | E2F/DP | ||||||||
Protein Properties | Length: 469aa MW: 50829.8 Da PI: 4.7275 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 85 | 6e-27 | 150 | 215 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++++gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+irwkg Sevir.1G187500.2.p 150 RYDSSLGLLTKKFINLLKQAPDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 215 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 7.1E-29 | 147 | 217 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 4.63E-18 | 150 | 213 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.0E-35 | 150 | 215 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.4E-24 | 152 | 215 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.71E-49 | 225 | 331 | No hit | No description |
SuperFamily | SSF144074 | 9.68E-35 | 227 | 331 | No hit | No description |
Pfam | PF16421 | 1.8E-33 | 230 | 329 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 469 aa Download sequence Send to blast |
MSGVGSGRPP AAQKILQSLR PPLAFASPSR PPFAAPDDYH RFPTPAAAAA PAATSGGVGA 60 GGAADSIEEG LVIRTPLKRK ATSEENDAAE SSECIITSTG FTGSPMLTPV SGKTVKTSKS 120 KAKNNKAGPQ TPTSNVGSPL NPATPAGTCR YDSSLGLLTK KFINLLKQAP DGILDLNNAA 180 ETLEVQKRRI YDITNVLEGI GLIEKTLKNR IRWKGLDDSG VDLDNGISAL QAEVENLSLQ 240 EQALDERISD MREKLRGLTE DENNQRWLYV TEDDIKGLPC FQNETLIAIK APHGTTLEVP 300 DPDEAGDYLQ RRYRIVLRST MGPIDVYLVS QFDEKFEELG GVETPARHAN MSRHHTVEDF 360 NATNAGQCST SMDVVHNVQQ NQRTPQDPNA SHDFGGMTRI IPSDVDTDAD YWLLTEGDVS 420 ITDMWKTAQV QWDQMDFLSE EVVTPRAQNQ QPVAVGGPHM QVPSMDKP* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 3e-24 | 142 | 216 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Sevir.1G187500.2.p |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_004952668.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-137 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | K3YS64 | 0.0 | K3YS64_SETIT; Uncharacterized protein | ||||
STRING | Si017108m | 0.0 | (Setaria italica) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-124 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | Sevir.1G187500.2.p |
Publications ? help Back to Top | |||
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