PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PGSC0003DMP400046799
Common NameLOC102595532
Organism
Solanum tuberosum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family HD-ZIP
Protein Properties Length: 716aa    MW: 78677.3 Da    PI: 6.4556
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PGSC0003DMP400046799genomePGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.41.2e-183384556
                          SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
              Homeobox  5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                          +++t++q++ Le++F+++++p+++ r +L++ lgL  rq+k+WFqNrR++ k
  PGSC0003DMP400046799 33 HRHTAHQIQSLESVFKECPHPDEKIRLQLSRDLGLAPRQIKFWFQNRRTQLK 84
                          689*********************************************9987 PP
2START172.62.5e-542254502206
                           HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S... CS
                 START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla... 77 
                           +a  a++el+++ + +ep+W+ks     + ++ d + q+f+++++       ++ea+r sgvv+m+   lv  ++d++ +W e ++   
  PGSC0003DMP400046799 225 IAGNAMEELIRLLQTNEPLWTKSTadgrDVLDIDNYDQIFPKANSslknpnVRVEASRQSGVVIMNGLALVDMFMDVN-KWVEFFPtiv 312
                           67899*********************9999999999999999988999**99**************************.********** PP

                           .EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEEC CS
                 START  78 .kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepks 158
                            ka tlevis g      ++lqlm+ e q+lsplvp R f+f+R+++q + g+w+ivdvS d +q++   +s+ ++++lpSg+li++++
  PGSC0003DMP400046799 313 sKARTLEVISCGmmgsrsSTLQLMYEEQQVLSPLVPtRQFYFLRFCQQIETGSWAIVDVSYDITQENMYPPSSCKVHKLPSGCLIQDMP 401
                           *****************************************************************998899****************** PP

                           TCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                 START 159 nghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                           ng+skvtw+ehv+++++   h l+r l+ sg+a+ga +w+  lqr+ce+
  PGSC0003DMP400046799 402 NGYSKVTWLEHVEVEEKGSiHRLYRDLIYSGMAFGAERWLGSLQRLCER 450
                           **************998666***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.17E-181386IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.603.2E-201680IPR009057Homeodomain-like
PROSITE profilePS5007117.0222686IPR001356Homeobox domain
SMARTSM003892.1E-182790IPR001356Homeobox domain
CDDcd000861.26E-172887No hitNo description
PfamPF000462.8E-163384IPR001356Homeobox domain
PROSITE patternPS0002706184IPR017970Homeobox, conserved site
PROSITE profilePS5084849.009215453IPR002913START domain
SuperFamilySSF559611.16E-36216452No hitNo description
CDDcd088752.72E-114219449No hitNo description
SMARTSM002341.1E-42224450IPR002913START domain
PfamPF018522.5E-46225450IPR002913START domain
Gene3DG3DSA:3.30.530.205.7E-6230260IPR023393START-like domain
Gene3DG3DSA:3.30.530.205.7E-6333422IPR023393START-like domain
SuperFamilySSF559611.34E-19471680No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 716 aa     Download sequence    Send to blast
MEYGTGGGGG GGGGASSSGG DATDAHRKKK RFHRHTAHQI QSLESVFKEC PHPDEKIRLQ  60
LSRDLGLAPR QIKFWFQNRR TQLKSQHERA DNSALRSEND RIRCENIAIR EAIKNVICPS  120
CGGPPVTEDT YFDEQKLRME NLQLKEELDK ISSIAAKYMG RPISQLPPVQ PVHLSSLNLM  180
SMPNFGLTGP SLDLDLLPGS LSTYPNLPCP TLNISDMDKS LMADIAGNAM EELIRLLQTN  240
EPLWTKSTAD GRDVLDIDNY DQIFPKANSS LKNPNVRVEA SRQSGVVIMN GLALVDMFMD  300
VNKWVEFFPT IVSKARTLEV ISCGMMGSRS STLQLMYEEQ QVLSPLVPTR QFYFLRFCQQ  360
IETGSWAIVD VSYDITQENM YPPSSCKVHK LPSGCLIQDM PNGYSKVTWL EHVEVEEKGS  420
IHRLYRDLIY SGMAFGAERW LGSLQRLCER YACLMVSGNS SRELGGVIPS PEGKKSMMKV  480
AQRMVSSFCA SINPSNGHQW NNISTLDEFE VRATLQKCTD PGQPNGVVIS AASTIWLPVP  540
PQHVFNFLRD ERTRPQWDVL SNQNPVQEVA HIANGSHPGN SISVLRAYNT SQNNMLILQE  600
SCIDSSGSLV VYSPVDLQSI NIAMSGEDTT YIPLLPSGFT ISQDGRGSNE ALSMNNGSTM  660
GGAGAGGSLV TVVFQILVSS LSSSAKMSPE SVNTVNNLIG NTIHQIKTAL NCSTS*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapPGSC0003DMP400046799
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9755180.0HG975518.1 Solanum lycopersicum chromosome ch06, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006347370.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLM1CK980.0M1CK98_SOLTU; Uncharacterized protein
STRINGPGSC0003DMT4000693120.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Xu X, et al.
    Genome sequence and analysis of the tuber crop potato.
    Nature, 2011. 475(7355): p. 189-95
    [PMID:21743474]
  3. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  4. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  5. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  6. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  7. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  8. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  9. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  10. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  11. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]