PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | PGSC0003DMP400034104 | ||||||||
Common Name | LOC102593965 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 449aa MW: 49554.2 Da PI: 4.4971 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.3 | 2.2e-27 | 127 | 192 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg PGSC0003DMP400034104 127 RYDSSLGLLTKKFINLIKHAEDGMLDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 192 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.5E-29 | 125 | 193 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.9E-34 | 127 | 192 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.9E-17 | 127 | 190 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.7E-24 | 129 | 192 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 5.46E-50 | 203 | 309 | No hit | No description |
SuperFamily | SSF144074 | 7.06E-34 | 205 | 309 | No hit | No description |
Pfam | PF16421 | 1.1E-34 | 208 | 307 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 449 aa Download sequence Send to blast |
MKPQQQQQQQ QSLKRQLQFS SIKPVFGDYH RFSTEPVDCS SQEPPGIVVK TPPLKRKSAA 60 ANYGQGVGDR NPASGYANVN SPIQTPVSGK NAQKVPRTSK ARSASQAVTS NVGSPSGNNV 120 TPVGPCRYDS SLGLLTKKFI NLIKHAEDGM LDLNKAADTL EVQKRRIYDI TNVLEGIGLI 180 EKKLKNRIQW KGQGVSKPGE ADESVASLQA EVEKLTVEEH RLDDQIREMQ ESLRDLSEDE 240 NNQRWLFVTE DDIKSLPCFQ NETLIAIKAP HGTTLEVPDP DEAVDYPQRR YRIVLRSTMG 300 PIDVYLVSQF EEKFEEVNAV EAPPSVPSTS GLNEKATATL ATEENEEVDI GMEGKENQNV 360 RSEVGTSQDF MTGIMKIVPD VDNEADYWLL SDADVSITDM WRTESAIDWN ELDVIQEDYS 420 IANVSTPRAQ TPPPATTEVP SAANTYGC* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 9e-27 | 122 | 194 | 2 | 75 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | PGSC0003DMP400034104 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | BT012840 | 0.0 | BT012840.1 Lycopersicon esculentum clone 113908F, mRNA sequence. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_006362858.1 | 0.0 | PREDICTED: transcription factor E2FB | ||||
Swissprot | Q9FV71 | 1e-147 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | M1BQF2 | 0.0 | M1BQF2_SOLTU; Uncharacterized protein | ||||
STRING | Solyc11g068800.1.1 | 0.0 | (Solanum lycopersicum) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 1e-144 | E2F transcription factor 1 |
Link Out ? help Back to Top | |
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Phytozome | PGSC0003DMP400034104 |
Entrez Gene | 102593965 |
Publications ? help Back to Top | |||
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