PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PGSC0003DMP400008747
Organism
Solanum tuberosum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family AP2
Protein Properties Length: 654aa    MW: 71920.6 Da    PI: 7.4735
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PGSC0003DMP400008747genomePGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP251.62.3e-16300359155
                   AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                           s+y+GV++++++gr++A+++d  ++  g  ++ ++++lg ++ +e+Aa+a+++a++k++g
  PGSC0003DMP400008747 300 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqtRKgRQVYLGGYDMEEKAARAYDQAALKYWG 359
                           78*******************988886678446*************************98 PP
2AP2461.3e-14402453155
                   AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                           s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  PGSC0003DMP400008747 402 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDVAAIKFRG 453
                           57****************988532...5************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541711.37E-16300369IPR016177DNA-binding domain
CDDcd000188.75E-22300367No hitNo description
PfamPF008479.4E-13300359IPR001471AP2/ERF domain
SMARTSM003801.9E-29301373IPR001471AP2/ERF domain
PROSITE profilePS5103218.913301367IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.3E-16301368IPR001471AP2/ERF domain
PRINTSPR003673.1E-6302313IPR001471AP2/ERF domain
SuperFamilySSF541717.85E-18402463IPR016177DNA-binding domain
PfamPF008475.2E-10402453IPR001471AP2/ERF domain
CDDcd000186.05E-26402463No hitNo description
PROSITE profilePS5103219.124403461IPR001471AP2/ERF domain
SMARTSM003801.1E-34403467IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.8E-18403461IPR001471AP2/ERF domain
PRINTSPR003673.1E-6443463IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007276Biological Processgamete generation
GO:0010492Biological Processmaintenance of shoot apical meristem identity
GO:0042127Biological Processregulation of cell proliferation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 654 aa     Download sequence    Send to blast
MKAMNDDSRS NNNNNHNSAA ANSNWLGFSL SPHMKMEVTN SSETQHQHQF AQSFYLSSSP  60
PPPMNVSTTS ALCYENNPFH SSLSVMPLKS DGSLCIMEAL SRSHADAMVQ SSSPKLEDFL  120
GGASMGNSQY GSHDREAMAL SLDSMYYHQN EEEIQVHSHH PYYSPMHCHG MYHQESLLEE  180
TKPTQISNSD AQMTGNELKS WGHYAEQHAI DQHINATCSM VAAAAAAAGG GGGTSGCNDL  240
QSLSLSMNPG SQSSCVTPRQ ISPTGLECVA VESKKRASGK VAQKQPVHRK SIDTFGQRTS  300
QYRGVTRHRW TGRYEAHLWD NSCKKEGQTR KGRQVYLGGY DMEEKAARAY DQAALKYWGP  360
STHINFPLEN YQKELDDMKN MTRQEYVAHL RRKSSGFSRG ASIYRGVTRH HQHGRWQARI  420
GRVAGNKDLY LGTFSTQEEA AEAYDVAAIK FRGVNAVTNF DISRYDVEKI MASNTLPAGE  480
LARRTKEREP IEYNNNNNNN NIGGVGGHKN EECVDNNNNG NITDWKMVLY QTSNPSLGLN  540
YRNPTSFSMA LQDLIGIDSM TNSNNHHATI LDHEQNKIGN HFSNASSLVT SLGSSREPSP  600
DKSATAASLV FAKPTKFAVP TATSVNACIP SAQLRPIPVS MAHLPVFAAL NDA*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00088SELEXTransfer from AT4G37750Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapPGSC0003DMP400008747
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB1812030.0AB181203.1 Solanum lycopersicum LeANT mRNA for AINTEGUMENTA homolog, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006356836.10.0PREDICTED: AP2-like ethylene-responsive transcription factor ANT
RefseqXP_006356837.10.0PREDICTED: AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-164ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLM1A1H20.0M1A1H2_SOLTU; Uncharacterized protein
STRINGPGSC0003DMT4000125880.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20742460
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-164AP2 family protein
Publications ? help Back to Top
  1. Xu X, et al.
    Genome sequence and analysis of the tuber crop potato.
    Nature, 2011. 475(7355): p. 189-95
    [PMID:21743474]
  2. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  3. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  4. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  5. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  6. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  7. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  8. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  9. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  10. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  11. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  12. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]