PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SapurV1A.0408s0190.2.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix
Family HB-other
Protein Properties Length: 231aa    MW: 26423.8 Da    PI: 5.4746
Description HB-other family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SapurV1A.0408s0190.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox15.23.6e-053521451
                            HHHHHHHH..SSS--HHHHHHHHHHC..........TS-HHHHHHHHHHH CS
                Homeobox 14 eLeelFek..nrypsaeereeLAkkl..........gLterqVkvWFqNr 51
                            e+e+lF++  +  +  +  e+LA++            +t rqV+ WFq r
  SapurV1A.0408s0190.2.p  3 EMENLFKEsrEEALAPQFCEKLASSFsyapsragkeAITPRQVQSWFQDR 52
                            799999975688999999*******9********99************88 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS500719.167159IPR001356Homeobox domain
PfamPF167197.9E-4098225IPR032001SAWADEE domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006306Biological ProcessDNA methylation
GO:0006346Biological Processmethylation-dependent chromatin silencing
GO:0031047Biological Processgene silencing by RNA
GO:0003677Molecular FunctionDNA binding
GO:0003682Molecular Functionchromatin binding
Sequence ? help Back to Top
Protein Sequence    Length: 231 aa     Download sequence    Send to blast
MLEMENLFKE SREEALAPQF CEKLASSFSY APSRAGKEAI TPRQVQSWFQ DRLKKSQPQV  60
ASSNMALKLL TNLSDASTSF GATESSQKLK GNASDLSELI FEALSSKDNA WYDIASFLNY  120
RVLCSGELEV RVRFAGFRNT DDEWVNVRRA VRERSIPLEP SECQRVKVGD LVLCFQEREE  180
RAVYCDAHVL EINRQLHDIN SCRCTFVVRY DHDDIEEKVQ LDRLCRRPTP *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4iuq_A1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
4iuq_B1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
4iur_A1e-60972282133SHH1 SAWADEE
4iur_B1e-60972282133SHH1 SAWADEE
4iut_A1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
4iut_B1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
4iuu_A1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
4iuu_B1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
4iuv_A1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
4iuv_B1e-60972282133SAWADEE HOMEODOMAIN HOMOLOG 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in RNA-directed DNA methylation (RdDM). Required for the silencing of some endogenous RdDM targets and accumulation of 24-nt siRNAs, but not for the production of Pol V-dependent transcripts. Functions in transcriptional silencing through both DNA methylation-dependent and -independent pathways. Required for both maintenance and de-novo DNA methylation. Plays a role in the recruitment of Pol IV to genomic regions associated with K9 methylated histone H3 that are targets for RdDM. {ECO:0000269|PubMed:21811420, ECO:0000269|PubMed:22064704, ECO:0000269|PubMed:23636332, ECO:0000269|PubMed:23637343}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSapurV1A.0408s0190.2.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCU2314782e-31CU231478.1 Populus EST from mild drought-stressed leaves.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002299736.11e-152protein SAWADEE HOMEODOMAIN HOMOLOG 1 isoform X1
SwissprotQ9XI476e-86SHH1_ARATH; Protein SAWADEE HOMEODOMAIN HOMOLOG 1
TrEMBLB9GGM11e-151B9GGM1_POPTR; Uncharacterized protein
STRINGPOPTR_0001s19000.11e-152(Populus trichocarpa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G18380.12e-56sequence-specific DNA binding transcription factors;sequence-specific DNA binding
Publications ? help Back to Top
  1. Liu J, et al.
    An atypical component of RNA-directed DNA methylation machinery has both DNA methylation-dependent and -independent roles in locus-specific transcriptional gene silencing.
    Cell Res., 2011. 21(12): p. 1691-700
    [PMID:22064704]
  2. Law JA, et al.
    Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
    Nature, 2013. 498(7454): p. 385-9
    [PMID:23636332]
  3. Ma L, et al.
    Angiosperms Are Unique among Land Plant Lineages in the Occurrence of Key Genes in the RNA-Directed DNA Methylation (RdDM) Pathway.
    Genome Biol Evol, 2015. 7(9): p. 2648-62
    [PMID:26338185]
  4. Wang F,Axtell MJ
    AGO4 is specifically required for heterochromatic siRNA accumulation at Pol V-dependent loci in Arabidopsis thaliana.
    Plant J., 2017. 90(1): p. 37-47
    [PMID:28002617]