PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SapurV1A.0385s0090.2.p
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix
Family LSD
Protein Properties Length: 172aa    MW: 18003.9 Da    PI: 8.3241
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SapurV1A.0385s0090.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
                 zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                            C gC  +L YP GA++V+CalC tV
  SapurV1A.0385s0090.2.p  7 CRGCASVLLYPSGATNVCCALCSTV 31
                            9**********************99 PP

                 zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                            C gCr lL+YP GA+sVRC++C++V
  SapurV1A.0385s0090.2.p 46 CRGCRSLLMYPHGATSVRCSCCHAV 70
                            9***********************9 PP

                 zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                             Cg+C t+L+YP G+psV+C++C+ V
  SapurV1A.0385s0090.2.p  84 CGNCWTTLMYPNGSPSVKCPVCQYV 108
                             **********************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010534.7E-9434IPR005735Zinc finger, LSD1-type
PfamPF069437.2E-8731IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010533.9E-154372IPR005735Zinc finger, LSD1-type
PfamPF069431.4E-114670IPR005735Zinc finger, LSD1-type
Gene3DG3DSA: finger, RING/FYVE/PHD-type
TIGRFAMsTIGR010533.8E-1081111IPR005735Zinc finger, LSD1-type
PfamPF069432.4E-1284108IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 172 aa     Download sequence    Send to blast
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Cis-element ? help Back to Top
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1826842e-43AC182684.2 Populus trichocarpa clone Pop1-37C15, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024462592.11e-109protein LOL2 isoform X3
SwissprotP940773e-66LSD1_ARATH; Protein LSD1
TrEMBLA0A2K2CD301e-107A0A2K2CD30_POPTR; Uncharacterized protein
STRINGPOPTR_0001s43300.11e-106(Populus trichocarpa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.75e-66LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382