PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 270395
Common NameSELMODRAFT_270395
Organism
Selaginella moellendorffii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Lycopodiidae; Selaginellales; Selaginellaceae; Selaginella
Family LSD
Protein Properties Length: 197aa    MW: 20621.1 Da    PI: 8.1128
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
270395genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD1421.5e-132650125
  zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
             CggCrtlL YP GA++VRCalC  V
   270395 26 CGGCRTLLVYPQGATNVRCALCSSV 50
             **********************876 PP
2zf-LSD145.21.5e-146589125
  zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
             CggCrtlL+Y rGA+sV+C++C+t+
   270395 65 CGGCRTLLMYVRGATSVQCSCCHTI 89
             ***********************97 PP
3zf-LSD1413e-13103127125
  zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
              CggC t+L+Y +GA sV+CalC+ V
   270395 103 CGGCNTTLMYAFGAQSVKCALCQYV 127
              ***********************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010531.2E-142351IPR005735Zinc finger, LSD1-type
PfamPF069432.9E-122650IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010533.9E-166291IPR005735Zinc finger, LSD1-type
PfamPF069431.4E-126589IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010531.9E-11100130IPR005735Zinc finger, LSD1-type
PfamPF069431.4E-11103127IPR005735Zinc finger, LSD1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000303Biological Processresponse to superoxide
GO:0001666Biological Processresponse to hypoxia
GO:0002240Biological Processresponse to molecule of oomycetes origin
GO:0009626Biological Processplant-type hypersensitive response
GO:0009862Biological Processsystemic acquired resistance, salicylic acid mediated signaling pathway
GO:0010104Biological Processregulation of ethylene-activated signaling pathway
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0010602Biological Processregulation of 1-aminocyclopropane-1-carboxylate metabolic process
GO:0010618Biological Processaerenchyma formation
GO:0043069Biological Processnegative regulation of programmed cell death
Sequence ? help Back to Top
Protein Sequence    Length: 197 aa     Download sequence    Send to blast
MPVPLVPYAP QPHMPPPPGS QGQLICGGCR TLLVYPQGAT NVRCALCSSV TPVPPPGTEM  60
AQLVCGGCRT LLMYVRGATS VQCSCCHTIN LAMEANQVAH ISCGGCNTTL MYAFGAQSVK  120
CALCQYVTTI PHLSNARMPL PVQRPNYAPL PQPASVSEPA PTRQPSQTVV VENPMTMDES  180
GKLVTSVAVG VTTEKK*
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002963886.11e-138protein LOL1
SwissprotP940772e-60LSD1_ARATH; Protein LSD1
TrEMBLD8QX571e-137D8QX57_SELML; Uncharacterized protein
STRINGEFJ357571e-138(Selaginella moellendorffii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP11461753
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.72e-62LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Banks JA, et al.
    The Selaginella genome identifies genetic changes associated with the evolution of vascular plants.
    Science, 2011. 332(6032): p. 960-3
    [PMID:21551031]
  3. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  4. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  5. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]