PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00023008-RA_Salv

Common Name

WRKY59

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

WRKY

Protein Properties

Length: 352aa MW: 38286 Da PI: 8.1887

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00023008-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.1	5e-30	121	180	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt + +Cpv+k+v+r ed++++++tYeg+Hnh+ SMil_00023008-RA_Salv 121 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVSpSCPVRKQVQRFIEDTSILITTYEGSHNHP 180 58************************999**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	6.0E-31	106	182	IPR003657	WRKY domain
SuperFamily	SSF118290	2.09E-27	114	182	IPR003657	WRKY domain
PROSITE profile	PS50811	28.61	116	182	IPR003657	WRKY domain
SMART	SM00774	5.4E-35	121	181	IPR003657	WRKY domain
Pfam	PF03106	1.2E-26	122	180	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 352 aa Download sequence Send to blast
MMMMMVQEEE VIGIREENLR LKTLLQKIEM DYKNLQMKLS DFQQESKKSA EMSGDDEDQE 60 LVSLRLGSKS TMDRNDVVKA GSGAPMKTAV KTQRNGDDET SQTSVKKARV CVRARCDTPT 120 MNDGCQWRKY GQKIAKGNPC PRAYYRCTVS PSCPVRKQVQ RFIEDTSILI TTYEGSHNHP 180 LPLAATAMAS TTSAAASMLL SGSSASQPSA APLNRYGQPP PYFISNSSSN SSPTITLDLI 240 ANPSTLYSST SPTNPRCPTT NLSFTSMDSN TVPAVWGGGG GGNSYHHLLQ QQKFETSYVG 300 NPNYQAPSQQ ALTETLTKVI SSDPSFRSAI AAVISTMAAN GRCSEDGRRD EG

Sequence ? help Back to Top

Protein Sequence Length: 352 aa Download sequence Send to blast

MMMMMVQEEE VIGIREENLR LKTLLQKIEM DYKNLQMKLS DFQQESKKSA EMSGDDEDQE  60
LVSLRLGSKS TMDRNDVVKA GSGAPMKTAV KTQRNGDDET SQTSVKKARV CVRARCDTPT  120
MNDGCQWRKY GQKIAKGNPC PRAYYRCTVS PSCPVRKQVQ RFIEDTSILI TTYEGSHNHP  180
LPLAATAMAS TTSAAASMLL SGSSASQPSA APLNRYGQPP PYFISNSSSN SSPTITLDLI  240
ANPSTLYSST SPTNPRCPTT NLSFTSMDSN TVPAVWGGGG GGNSYHHLLQ QQKFETSYVG  300
NPNYQAPSQQ ALTETLTKVI SSDPSFRSAI AAVISTMAAN GRCSEDGRRD EG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	6e-22	108	182	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM823182	0.0	KM823182.1 Salvia miltiorrhiza WRKY protein (WRKY59) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011098771.1	1e-116	probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	9e-71	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A0D5YA42	0.0	A0A0D5YA42_SALMI; WRKY protein (Fragment)
STRING	cassava4.1_026182m	4e-87	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA12805	19	21

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	5e-55	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]