PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00020713-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family WRKY
Protein Properties Length: 393aa    MW: 43828 Da    PI: 8.4521
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00020713-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY108.14.4e-34158214259
                            --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                   WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                            dDgynWrKYGqK+vkgsefprsYY+Ct ++Cpvkkkvers  d++++ei+Y+g+Hnh+
  SMil_00020713-RA_Salv 158 DDGYNWRKYGQKQVKGSEFPRSYYKCTRSDCPVKKKVERSL-DGQITEIIYKGQHNHP 214
                            8****************************************.***************8 PP
2WRKY1062e-33279337159
                            ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                   WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                            ldDgy+WrKYGqK+vkg+++prsYY+Cts+gC+v+k+ver+a+d k+v++tYeg+Hnh+
  SMil_00020713-RA_Salv 279 LDDGYRWRKYGQKVVKGNPHPRSYYKCTSQGCNVRKHVERAATDAKAVITTYEGKHNHD 337
                            59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.807.3E-30150216IPR003657WRKY domain
SuperFamilySSF1182903.01E-26155216IPR003657WRKY domain
SMARTSM007742.0E-36157215IPR003657WRKY domain
PROSITE profilePS5081124.019158216IPR003657WRKY domain
PfamPF031062.1E-26158214IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.5E-37264339IPR003657WRKY domain
SuperFamilySSF1182901.57E-29271339IPR003657WRKY domain
PROSITE profilePS5081138.549274339IPR003657WRKY domain
SMARTSM007741.4E-39279338IPR003657WRKY domain
PfamPF031065.4E-26280337IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 393 aa     Download sequence    Send to blast
LFASVPLVFL LCFVFSNKQE IQSQKKGKSM AENESPPPAS TTAPMTLLSG FFPENDPDIY  60
CRSFSQLLMP SFGQPAEFMF QQNRPAGLVV SPPLAMLTVP PGLSPASLLD SPQGMVGAGE  120
QHDFHSSSTT FSLQRNVPPR VPEISQMKSQ LVVDKPADDG YNWRKYGQKQ VKGSEFPRSY  180
YKCTRSDCPV KKKVERSLDG QITEIIYKGQ HNHPRPARRA TDCSTDQDSV SASTDSEADG  240
DEHESKRRRV GETSEQALSR RTVTEPRIIV QTTSEVDLLD DGYRWRKYGQ KVVKGNPHPR  300
SYYKCTSQGC NVRKHVERAA TDAKAVITTY EGKHNHDIPA AKTSSHSSAA ASQLRPVNEL  360
AERYGGDDQR LPHMKEEQDS IASSQNNWKI YNS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A3e-41158340878Probable WRKY transcription factor 4
2lex_A3e-41158340878Probable WRKY transcription factor 4
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1245249KRRRV
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKM8231470.0KM823147.1 Salvia miltiorrhiza WRKY protein (WRKY24) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012847588.11e-132PREDICTED: probable WRKY transcription factor 3
SwissprotQ9XI901e-101WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A0D5YA110.0A0A0D5YA11_SALMI; WRKY protein
STRINGMigut.L01234.1.p1e-132(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA41072445
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.11e-101WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]