PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00017453-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family HD-ZIP
Protein Properties Length: 858aa    MW: 94634.5 Da    PI: 6.216
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00017453-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.31.3e-183795357
                           --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
               Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                           k  ++t+eq+++Le+l++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  SMil_00017453-RA_Salv 37 KYVRYTPEQVDALERLYHECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 95
                           5679*****************************************************97 PP
2START183.71e-571813892205
                            HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT. CS
                  START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg. 88 
                            +aee+++e+++ka+ ++  Wv+++ +++g++++ +++ s+++sg a+ra+g+v  +++  v+e+l+d++ W ++++++++l+v s+g 
  SMil_00017453-RA_Salv 181 IAEETLTEFLSKATGTAVEWVQMPGMKPGPDSIGIIAISHGCSGVASRACGLVGLEPT-RVAEILKDRPSWYRDCRAVDVLNVMSTGn 267
                            789*******************************************************.8888888888******************* PP

                            .EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE CS
                  START  89 .galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvd 171
                             g+++lm+++l+a+++l+p Rdf+ +Ry+  +++g++v++++S++++q+ p+    +++vRaellpSg+li+p+++g+s +++v+h+d
  SMil_00017453-RA_Salv 268 gGTIELMYMQLYAPTTLAPaRDFWLLRYTSVMEDGSLVVCERSLNNTQNGPSmppVQHFVRAELLPSGYLIRPCEGGGSIIHIVDHMD 355
                            **************************************************9988899******************************* PP

                            --SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXX CS
                  START 172 lkgrlphwllrslvksglaegaktwvatlqrqce 205
                            l+ ++++++lr+l++s++   ++t++a+l+++++
  SMil_00017453-RA_Salv 356 LEPWSVPEVLRPLYESSTLLSQRTTLAALRQLRQ 389
                            ******************************9876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.4673296IPR001356Homeobox domain
SMARTSM003891.2E-1534100IPR001356Homeobox domain
CDDcd000861.79E-163797No hitNo description
SuperFamilySSF466897.7E-1737100IPR009057Homeodomain-like
PfamPF000463.6E-163895IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.601.1E-183995IPR009057Homeodomain-like
CDDcd146861.44E-689128No hitNo description
PROSITE profilePS5084826.392171386IPR002913START domain
CDDcd088751.46E-79175390No hitNo description
SMARTSM002343.6E-42180390IPR002913START domain
SuperFamilySSF559611.13E-36180387No hitNo description
Gene3DG3DSA:3.30.530.206.2E-23180386IPR023393START-like domain
PfamPF018524.2E-55181389IPR002913START domain
PfamPF086701.9E-51715857IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010067Biological Processprocambium histogenesis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0010089Biological Processxylem development
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 858 aa     Download sequence    Send to blast
LRASEETRRY LLPSNNPTVM MAVTSACKDK MGIDNGKYVR YTPEQVDALE RLYHECPKPS  60
SLRRQQLIRE CPILSNIEPK QIKVWFQNRR CREKQRKEAS RLQAVNRKLT AMNKLLMEEN  120
DRLQKQVSHL VYENSFFRQQ TQNGTLASTD NSCESVVTSG QHHLTPQDPP KDASPAGLLS  180
IAEETLTEFL SKATGTAVEW VQMPGMKPGP DSIGIIAISH GCSGVASRAC GLVGLEPTRV  240
AEILKDRPSW YRDCRAVDVL NVMSTGNGGT IELMYMQLYA PTTLAPARDF WLLRYTSVME  300
DGSLVVCERS LNNTQNGPSM PPVQHFVRAE LLPSGYLIRP CEGGGSIIHI VDHMDLEPWS  360
VPEVLRPLYE SSTLLSQRTT LAALRQLRQI SQEVSQPNVT GWGRRPSALR ALGQRLSRGF  420
NEAVNGFTDE GWSMIESDGI DDVTVHVNSS PGKLMGTILT YANGFPSMSN AVLCAKASML  480
LQNVPPAILL RFLREHRSEW ADSGIDAYSV AAVKAGPCSI PVSRVGCFGG QVILPLAHTI  540
ENEEFMEVIR LENMAQYRDD VVMPSDIFLL QVCNGVDENA VGTCAELIFA PIDASFSDDA  600
PLLPSGFRII PLESKADASS PNRTLDLAST LEVGAAGGRA CGDQMRSQGT AKSVMTIAFQ  660
FAFEMHLQES VAAMARQYVR SIIASVQRVA LALSPSRLAP HAALRPPPAT PEAQTLARWI  720
YQSYRFFLGV ELLKPAAEGN DSILKTLWHH SDAVLCCSLK ALPVFTFANQ AGLDMLETTL  780
VALQDITLEK IFNDDGKKTL FAELPQIMQQ GFACLQGGIC LSSMGRPISY ERAVAWKVLN  840
EEEDAHCLCF MFVNWSFV
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269|PubMed:11402194, ECO:0000269|PubMed:15598805}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165. {ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:8575317}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011081776.10.0homeobox-leucine zipper protein ATHB-15
SwissprotQ391230.0ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBLA0A4D9B7850.0A0A4D9B785_SALSN; Homeobox-leucine zipper protein
STRINGMigut.A00196.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA45724140
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32880.10.0homeobox gene 8
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M
    Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis.
    Planta, 2014. 239(5): p. 989-1001
    [PMID:24488524]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  5. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  6. Liu S, et al.
    Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 388
    [PMID:26082787]
  7. Yamaguchi YL, et al.
    Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots.
    Front Plant Sci, 2017. 8: p. 1195
    [PMID:28747918]
  8. Yamazaki K, et al.
    Suppression of DELLA signaling induces procambial cell formation in culture.
    Plant J., 2018. 94(1): p. 48-59
    [PMID:29383774]