PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00013304-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

bHLH

Protein Properties

Length: 205aa MW: 22903.9 Da PI: 6.3607

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00013304-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.5	1.1e-08	118	158	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L SMil_00013304-RA_Salv 118 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 158 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.218	109	158	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.31E-14	114	170	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.9E-13	114	167	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.1E-13	115	164	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.2E-6	119	158	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.97E-6	132	163	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 205 aa Download sequence Send to blast
MDIGFMKSDQ IEMMLMQMDK LPDFSAAFDD DDSDDNPNIT GNNNNNVDAF ENFNVQSPPA 60 YDGFHGQQDP PAASSMAAMR EMIFRIAAMQ PVHIDPESVK RPKRKNVRIS TDPQSVAARH 120 RRERISERIR ILQRLVPGGT KMDTASMLDE AIHYVKFLKS QVQSLERVAA ARPEPPGVGF 180 PVPMSSGSYF PPPPPAAKGY HNVQY

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP257454	0.0	KP257454.1 Salvia miltiorrhiza clone 21 basic helix-loop-helix transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022880750.1	3e-76	transcription factor HEC1-like
Swissprot	Q9FHA7	2e-46	HEC1_ARATH; Transcription factor HEC1
TrEMBL	A0A0H3YBR2	1e-148	A0A0H3YBR2_SALMI; Basic helix-loop-helix transcription factor
STRING	Migut.N02717.1.p	4e-68	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	1e-40	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Vercruyssen L, et al. ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development. Plant Cell, 2014. 26(1): p. 210-29 [PMID:24443518] Sparks EE,Benfey PN HEC of a job regulating stem cells. Dev. Cell, 2014. 28(4): p. 349-50 [PMID:24576420] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667]