PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00012017-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family HB-other
Protein Properties Length: 289aa    MW: 33629.9 Da    PI: 5.5945
Description HB-other family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00012017-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox28.23.2e-092312652155
                            HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
               Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                            k +yp+++++  LA+ +gL+++q+ +WF N+R ++
  SMil_00012017-RA_Salv 231 KWPYPTEADKIALAEMTGLDQKQINNWFINQRKRH 265
                            569*****************************885 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012551.6E-2063107IPR005540KNOX1
PfamPF037903.4E-2165105IPR005540KNOX1
SMARTSM012561.8E-21109160IPR005541KNOX2
PfamPF037915.1E-20114159IPR005541KNOX2
PROSITE profilePS5007112.503205268IPR001356Homeobox domain
SuperFamilySSF466893.98E-18206276IPR009057Homeodomain-like
SMARTSM003893.6E-11207272IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.601.5E-26210268IPR009057Homeodomain-like
CDDcd000863.02E-11219268No hitNo description
PfamPF059206.9E-17225264IPR008422Homeobox KN domain
PROSITE patternPS000270243266IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010073Biological Processmeristem maintenance
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 289 aa     Download sequence    Send to blast
LMSPENMMMA EEYNQYHYHS PINSGDKYHH RIPMLGSDEL GFQSSVVSHD SASVNVQNQR  60
DEDEMKAKIA SHPSYSKLLD AYIDCQKVGA PPEIVSVLDE MRRENPDTVS VCTELDPQLD  120
EFMETYRHIL VKYKSDLSRP FDEATSFLNE IQTQLLNLCN DEAAVWSDEE LMEQQDAETK  180
REDRLLKEKL VRMYGSHISS LKLEFSKKKK KGKLPKEGRQ SLLAWWNLHS KWPYPTEADK  240
IALAEMTGLD QKQINNWFIN QRKRHWKSPD NMFAPDNLSP KPNFVPQDH
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011071110.11e-128homeobox protein knotted-1-like 6 isoform X1
SwissprotQ84JS67e-96KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A4D9BPY11e-137A0A4D9BPY1_SALSN; Uncharacterized protein
STRINGVIT_01s0127g00210.t011e-106(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA7532480
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.16e-89KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]