PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00011563-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family E2F/DP
Protein Properties Length: 426aa    MW: 46592.8 Da    PI: 6.8633
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00011563-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.52e-27128212271
                E2F_TDP   2 keksLrlltqkflklleksee.givtlnevakeLvse..................dvknkrRRiYDilNVLealnliekkekneirwk 70 
                            ++++Lr++++k   ++ek+e+ g++t+neva+eLv+e                  d+kn+rRR+YD+lNVL+a+++i+k +k+ei+wk
  SMil_00011563-RA_Salv 128 SGRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfsdpnnslaspdqsqqqyDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWK 211
                            689********...*****999*********************************************************.*******9 PP

                E2F_TDP  71 g 71 
                            g
  SMil_00011563-RA_Salv 212 G 212
                            8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094047.4E-12922425IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.104.2E-46123217IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.1E-35127212IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.28E-20130213IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023194.9E-25130212IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd144584.51E-36217362IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440743.4E-5218256No hitNo description
SMARTSM011383.5E-55219423IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440743.14E-32287378No hitNo description
PfamPF087814.4E-32287379IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 426 aa     Download sequence    Send to blast
LKLLGEFWAW LEFHVIFCGT MGNHSNNNSS NQEDGNKNSS TVSKGSGGLG GATRSWGTTV  60
SGGQSMSTSG SVGSPSSRSE AAMATTVSDS AIMRMNNLDI QGDDAGSQGT AGNRKKKRGQ  120
RAVGGDKSGR GLRQFSMKVC EKVESKGRTT YNEVADELVA EFSDPNNSLA SPDQSQQQYD  180
EKNIRRRVYD ALNVLMAMDI ISKDKKEIQW KGLPRTSLDD IEELKTERLG VRSRIEKKAA  240
YLEELEEQVS GHESIVYNSE FGWKSAPWCV YHVFLSNAMA NSLMPSVLLQ YVGLQNLIQR  300
NKQLYGSGNT PTGGVALPFI LVQTRPHATV EVEISEDMQL VHFDFNSTPF ELHDDNYVLK  360
AMKFAEKSRN DGTAQNNPTE GGESSSMATA YQTQGPHPSG SSISSRPPNS SPLPGILKAR  420
VKHEQH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B1e-39121217193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011079068.10.0LOW QUALITY PROTEIN: transcription factor-like protein DPB
SwissprotQ9FNY21e-148DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A4D8ZRR70.0A0A4D8ZRR7_SALSN; Uncharacterized protein
STRINGXP_010241817.10.0(Nelumbo nucifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA62652435
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.11e-132Transcription factor DP