PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00011004-RA_Salv
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family ARF
Protein Properties Length: 832aa    MW: 92787.4 Da    PI: 6.0628
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00011004-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B3573.5e-18138263199
                            EEEE-..-HHHHTT-EE--HHH.HTT................................---..--SEEEEEETTS-EEEEEE..EEET CS
                     B3   1 ffkvltpsdvlksgrlvlpkkfaeeh................................ggkkeesktltledesgrsWevkliyrkks 56 
                            f+k+lt sd+   + l +p++ aee                                 + +    ++l+ +d++  +W++++i+r+++
  SMil_00011004-RA_Salv 138 FCKTLTASDTVPWR-LLVPRRAAEESfptlgilscliildtnyfcsyshfplvpqdfsQTP--PAQELMARDLHDVEWKFRHIFRGQP 222
                            56666666666654.6667777766667777777777666666666677777777753333..4458********************* PP

                            TEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEEE-S CS
                     B3  57 gryvltkGWkeFvkangLkegDfvvFkldgrsefelvvkvfrk 99 
                            +r++lt+GW+ Fv+a++L +gD+v+F   ++++ +l+++++r+
  SMil_00011004-RA_Salv 223 KRHLLTTGWSVFVSAKRLVAGDSVLFI--WNEKNQLLLGIRRA 263
                            ***************************..8899999****997 PP
2Auxin_resp109.73.1e-36288372183
             Auxin_resp   1 aahaastksvFevvYnPr.astseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                            aahaa+t+s F+v+YnPr as+seFv++++k+ ka++ ++vsvGmRf+m fete+ss rr++Gt++++ dldpvrW nS+Wrs+k
  SMil_00011004-RA_Salv 288 AAHAAATNSCFTVFYNPRwASPSEFVISLSKYAKAVYhTRVSVGMRFRMLFETEESSVRRYMGTITSIGDLDPVRWANSHWRSVK 372
                            79***************85899**************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.22E-32129291IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.103.8E-34131277IPR015300DNA-binding pseudobarrel domain
CDDcd100177.59E-15137262No hitNo description
PfamPF023622.4E-16138263IPR003340B3 DNA binding domain
SMARTSM010192.1E-13138264IPR003340B3 DNA binding domain
PROSITE profilePS5086311.265172264IPR003340B3 DNA binding domain
PfamPF065071.5E-31288372IPR010525Auxin response factor
SuperFamilySSF542772.68E-7712792No hitNo description
PROSITE profilePS5174524.146718802IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009733Biological Processresponse to auxin
GO:0009908Biological Processflower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 832 aa     Download sequence    Send to blast
MKLSTSEMGQ QAHEGEKKCL NSELWHACAG PLVSLPTVGS RVVYFPQGHS EQVAATTNKE  60
VDAHIPNYPS LSPQLICQLH NVTMHADVET DEVYAQMTLQ PLTPIETDLN VLLDAARTKR  120
CISSGGAGMP NRQPTNYFCK TLTASDTVPW RLLVPRRAAE ESFPTLGILS CLIILDTNYF  180
CSYSHFPLVP QDFSQTPPAQ ELMARDLHDV EWKFRHIFRG QPKRHLLTTG WSVFVSAKRL  240
VAGDSVLFIW NEKNQLLLGI RRATRPQTVM PSSVLSSDSM HIGLLAAAAH AAATNSCFTV  300
FYNPRWASPS EFVISLSKYA KAVYHTRVSV GMRFRMLFET EESSVRRYMG TITSIGDLDP  360
VRWANSHWRS VKVGWDESTA GERQPRVSLW EIEPLTTFPM YPSLLPLRLK RPWYPGASSF  420
QGTSPTSSSN CTSISDAGSE AINGMPWLRG EVGEAGFNSI NFQSVGMLPW MQQRFDPTAL  480
RNDLNQQYQA IMAAGLQNQF QQPVDYLQQS GSHNPQTQQQ HTIQPSVPSL TLPLQTQMLS  540
DNMQRPTPHQ VSEENHTYQE AYLARHPSDI PSPWFTKSEF SNSASVTHPC VQNMLGSLCP  600
EGSSGNLVNS SRAGQATLDE QSPQHSWVAK YSGKDASMEQ ENCTLDVQDH QSLFGASVDS  660
GLLLPTTVSR VSTSSVQADM FPMPLGSSGF QSPLYSYVQD SSDLLHNTGQ VDQPTPDRIF  720
VKVYKMGSVG RSVDIGRFSS YEELRQELGQ MFRVEGLLED PQRSGWQLVF VDRENDILLL  780
GDDPWEAFVN NVWYIKILSP EDVVKLGKQE GDTGSVERTN NADVHNLPSL HY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-132139337388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00033PBMTransfer from AT5G37020Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKX0367300.0KX036730.1 Salvia miltiorrhiza auxin response factor ARF10 (ARF) gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022859801.10.0auxin response factor 8-like isoform X1
RefseqXP_022859802.10.0auxin response factor 8-like isoform X1
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A191T8S70.0A0A191T8S7_SALMI; Auxin response factor
STRINGXP_009612885.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA38572339
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]