PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | SMil_00006363-RA_Salv | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
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Family | E2F/DP | ||||||||
Protein Properties | Length: 329aa MW: 36832.6 Da PI: 6.6956 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 85.2 | 5.1e-27 | 70 | 135 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf+kl++ +++g+++ln a+ L +v ++RRiYDi+NVLe+++liek+ kn+irwkg SMil_00006363-RA_Salv 70 RYDNSLGLLTKKFIKLIQGAKDGTLDLNRTADVL---QV--QKRRIYDITNVLEGIGLIEKTTKNHIRWKG 135 689*******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 2.3E-28 | 67 | 136 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 8.07E-18 | 70 | 133 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.9E-34 | 70 | 135 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 5.6E-25 | 72 | 135 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.18E-34 | 146 | 249 | No hit | No description |
SuperFamily | SSF144074 | 2.88E-23 | 147 | 249 | No hit | No description |
Pfam | PF16421 | 2.0E-23 | 151 | 247 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0000902 | Biological Process | cell morphogenesis | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0042023 | Biological Process | DNA endoreduplication | ||||
GO:0051782 | Biological Process | negative regulation of cell division | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005730 | Cellular Component | nucleolus | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
GO:0046982 | Molecular Function | protein heterodimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 329 aa Download sequence Send to blast |
QPNELGSVGV NASLQIPKQE EVVNTFLLGP SSYVVGAKRV SKAKSSKNAK SVVQEAKLES 60 IDNFSLSSCR YDNSLGLLTK KFIKLIQGAK DGTLDLNRTA DVLQVQKRRI YDITNVLEGI 120 GLIEKTTKNH IRWKGFEMFG PKEQDDKVSH LKAEVELLRA EDRRLDDCIR QKLEDIRELT 180 SNQKNLFLTE EDIMSLPHLR NQTVIAIQAP RASFLEVPDP DEDIGFSQKQ HKLIVRSTTG 240 PIDVYLLSKK EQKSRDGSAK RAKLLDSLAR TSSSRVDEAD LSSSPDTSTS SKASGFQKIV 300 PFDVGIDDDY WLRSDHNVSI SDLWSSEEL |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 7e-24 | 67 | 135 | 4 | 73 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Involved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00190 | DAP | Transfer from AT1G47870 | Download |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011083529.1 | 1e-161 | transcription factor E2FC | ||||
Swissprot | Q9FV70 | 4e-84 | E2FC_ARATH; Transcription factor E2FC | ||||
TrEMBL | A0A4D8YT37 | 0.0 | A0A4D8YT37_SALSN; Uncharacterized protein | ||||
STRING | Migut.C00805.1.p | 1e-152 | (Erythranthe guttata) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA12625 | 20 | 22 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G47870.1 | 1e-84 | E2F/DP family protein |
Publications ? help Back to Top | |||
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