PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00004800-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

WRKY

Protein Properties

Length: 736aa MW: 78357.4 Da PI: 6.6258

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00004800-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	94.2	9.4e-30	272	331	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+aed +++++tYeg+Hnh+ SMil_00004800-RA_Salv 272 MNDGCQWRKYGQKISKGNPCPRAYYRCTVApSCPVRKQVQRCAEDMTILITTYEGTHNHP 331 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	3.6E-31	257	333	IPR003657	WRKY domain
SuperFamily	SSF118290	1.03E-26	264	333	IPR003657	WRKY domain
PROSITE profile	PS50811	28.346	267	333	IPR003657	WRKY domain
SMART	SM00774	1.9E-35	272	332	IPR003657	WRKY domain
Pfam	PF03106	7.0E-26	273	331	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 736 aa Download sequence Send to blast
MDISLHKSVL EEAVKEEGKP SESNGDEESC VDDIVLHQFG AGKRAQDNDG MKSPSPNKKN 60 SNCSNQGLAI TNMESRPSPE SESRSSSSAK KDQLDDQLGS TKAEMDEVME ENQRLKMYLD 120 GILKDYRTLQ MQYRDVMQQE ATTKLSPHHH DLMEAAADDG LIDLSLAMSS IDKKRKTPKM 180 NDDIEILDDN KQGLSLGLDC KFDLPEKSPI KPSPTLTPEN SIEEVKEEAG ETWPPKGVKN 240 ARDAGGEDEI SQQNPTKRAR VSVRVRCDTP TMNDGCQWRK YGQKISKGNP CPRAYYRCTV 300 APSCPVRKQV QRCAEDMTIL ITTYEGTHNH PLPMSATAMA STTSAAASML MSGSSTSGTG 360 PSTPSTTTTA SNLHGLNFYL SDNSRTTKPT FYLPNPSISS SPSYPTITLD LTSSSSSSSS 420 HLNRLGSGGG FAPRYSTTNL NFSSLESNPL PNSYNNAMLT YGQQSFNRNQ NAANSLSFGS 480 QPYETLYQSY LQKSISNPNP NQQHLGADTI AAATKAITSD PSFQTVLAAA LTSIIGGSGG 540 TAAANNHNAA EKSSGGDAFP ILSSFPPTSN ATKCAPSFMN KSSSSSSSQQ PGLSTLLSPP 600 FPFSSSNKSK SNSPADNRDH GQTPLQLTTK AITSDPSFQT VLAAALTSII GGSGGTAAAN 660 NHNAAEKSSG GDAFPILSSF PPTSNATKCA PSFMNKSSSS SSSQQPGLST LLSPPFPFSS 720 SNKSKSNSPA DNRDHV

Sequence ? help Back to Top

Protein Sequence Length: 736 aa Download sequence Send to blast

MDISLHKSVL EEAVKEEGKP SESNGDEESC VDDIVLHQFG AGKRAQDNDG MKSPSPNKKN  60
SNCSNQGLAI TNMESRPSPE SESRSSSSAK KDQLDDQLGS TKAEMDEVME ENQRLKMYLD  120
GILKDYRTLQ MQYRDVMQQE ATTKLSPHHH DLMEAAADDG LIDLSLAMSS IDKKRKTPKM  180
NDDIEILDDN KQGLSLGLDC KFDLPEKSPI KPSPTLTPEN SIEEVKEEAG ETWPPKGVKN  240
ARDAGGEDEI SQQNPTKRAR VSVRVRCDTP TMNDGCQWRK YGQKISKGNP CPRAYYRCTV  300
APSCPVRKQV QRCAEDMTIL ITTYEGTHNH PLPMSATAMA STTSAAASML MSGSSTSGTG  360
PSTPSTTTTA SNLHGLNFYL SDNSRTTKPT FYLPNPSISS SPSYPTITLD LTSSSSSSSS  420
HLNRLGSGGG FAPRYSTTNL NFSSLESNPL PNSYNNAMLT YGQQSFNRNQ NAANSLSFGS  480
QPYETLYQSY LQKSISNPNP NQQHLGADTI AAATKAITSD PSFQTVLAAA LTSIIGGSGG  540
TAAANNHNAA EKSSGGDAFP ILSSFPPTSN ATKCAPSFMN KSSSSSSSQQ PGLSTLLSPP  600
FPFSSSNKSK SNSPADNRDH GQTPLQLTTK AITSDPSFQT VLAAALTSII GGSGGTAAAN  660
NHNAAEKSSG GDAFPILSSF PPTSNATKCA PSFMNKSSSS SSSQQPGLST LLSPPFPFSS  720
SNKSKSNSPA DNRDHV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	8e-20	259	333	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM823138	0.0	KM823138.1 Salvia miltiorrhiza WRKY protein (WRKY15) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011071617.1	0.0	probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	1e-136	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A0D5Y9Z9	0.0	A0A0D5Y9Z9_SALMI; WRKY protein
STRING	Migut.I00135.1.p	1e-172	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	9e-62	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]