PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | SMil_00004720-RA_Salv | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
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Family | E2F/DP | ||||||||
Protein Properties | Length: 395aa MW: 44521.1 Da PI: 4.3851 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 80.9 | 1.1e-25 | 72 | 137 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++l+++se gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn i+wkg SMil_00004720-RA_Salv 72 RYDSSLALLTKKFINLIKHSEGGILELNKAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNIIQWKG 137 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.7E-27 | 70 | 138 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 7.75E-17 | 72 | 135 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 8.8E-33 | 72 | 137 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 8.8E-23 | 74 | 137 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 8.96E-43 | 150 | 254 | No hit | No description |
SuperFamily | SSF144074 | 3.4E-31 | 150 | 254 | No hit | No description |
Pfam | PF16421 | 6.4E-32 | 154 | 252 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 395 aa Download sequence Send to blast |
MADYGTISVE QNVSPATSAF MNSPHRTPVS VKSEKPQKVP KSTKANRVSC QSLMTNTGSP 60 TGDNLTPVGS CRYDSSLALL TKKFINLIKH SEGGILELNK AAETLEVQKR RIYDITNVLE 120 GIGLIEKTLK NIIQWKGTDV RRPGEVDETL PDIQEEIQNL NSEECRLDER IREMQEKLRG 180 LSEEEDNQRW LFITEEDVKN LPCFENETLI AIKAPHGTTL EVPEPDEAGD YPQRRYKIVL 240 RSTMGPIDVY LVSQFEEINA YEAQPSNLDT SVANETPKEE ITRDEIIAQG EGVQRMCLET 300 SSSHDFVSGI MKIVPDADSD ADYYLLSETD VSITDMWRTE DEVDWDTLNT LHEGYPVSII 360 SPSRDQAPRP KIRDCVQLLR MDGHCIVSSI IIMEI |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 4e-20 | 67 | 137 | 2 | 73 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011090314.1 | 1e-177 | transcription factor E2FB isoform X1 | ||||
Refseq | XP_020552667.1 | 1e-178 | transcription factor E2FB isoform X2 | ||||
Swissprot | Q9FV71 | 1e-124 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | A0A4D9A248 | 0.0 | A0A4D9A248_SALSN; Uncharacterized protein | ||||
STRING | XP_004140164.1 | 1e-161 | (Cucumis sativus) | ||||
STRING | Migut.N02463.1.p | 1e-161 | (Erythranthe guttata) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA1077 | 24 | 84 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 1e-127 | E2F transcription factor 1 |
Publications ? help Back to Top | |||
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