PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00004342-RA_Salv
Common NameMYB44
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family MYB
Protein Properties Length: 263aa    MW: 29890.3 Da    PI: 6.7413
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00004342-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding54.82.1e-171360148
                           TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
        Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                           rg W++eEde+l++ ++ +G g+W+++++  g+ R++k+c++rw +yl
  SMil_00004342-RA_Salv 13 RGLWSPEEDEKLIRHITTYGHGCWSSVPKLAGLQRCGKSCRLRWINYL 60
                           788*******************************************97 PP

2Myb_DNA-binding49.21.2e-1566109146
                            TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
        Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                            rg++ ++E+  ++d+++ lG++ W+ Ia++++ gRt++++k++w++
  SMil_00004342-RA_Salv  66 RGSFNEQEERTIIDVHRILGNR-WAQIAKHLP-GRTDNEVKNFWNS 109
                            899*******************.*********.***********96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.608.1E-27463IPR009057Homeodomain-like
PROSITE profilePS5129417.966860IPR017930Myb domain
SuperFamilySSF466891.2E-2810107IPR009057Homeodomain-like
SMARTSM007172.5E-131262IPR001005SANT/Myb domain
PfamPF002492.9E-151360IPR001005SANT/Myb domain
CDDcd001671.52E-111660No hitNo description
PROSITE profilePS5129425.05361115IPR017930Myb domain
Gene3DG3DSA:1.10.10.601.4E-2464116IPR009057Homeodomain-like
SMARTSM007174.3E-1565113IPR001005SANT/Myb domain
PfamPF002492.7E-1466109IPR001005SANT/Myb domain
CDDcd001679.76E-1168108No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 263 aa     Download sequence    Send to blast
MGHHCCSKQK VKRGLWSPEE DEKLIRHITT YGHGCWSSVP KLAGLQRCGK SCRLRWINYL  60
RPDLKRGSFN EQEERTIIDV HRILGNRWAQ IAKHLPGRTD NEVKNFWNSC IKKKLIAQGL  120
DPNTHNLLSS SSSSSSSSSY KPSYQQPFTV DTTTTAVVPI TTTATLHDQT SLINTHNSSL  180
PILNDINWAS LEQQSQQHNN SSCLYNKVDD DDDDDLILHD QHHLGTTFDP TCHFDFQFLD  240
SAFIAPQSFN SIMDDPLAWD IVN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A8e-32131157108B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that coordinates a small network of downstream target genes required for several aspects of plant growth and development, such as xylem formation and xylem cell differentiation, and lateral root formation (PubMed:22708996). Regulates a specific set of target genes by binding DNA to the AC cis-element 5'-ACCTAC-3' (PubMed:23741471). Functions as a transcriptional regulator of stomatal closure. Plays a role the regulation of stomatal pore size independently of abscisic acid (ABA) (PubMed:16005292). Required for seed coat mucilage deposition during the development of the seed coat epidermis (PubMed:19401413). Involved in the induction of trichome initiation and branching by positively regulating GL1 and GL2. Required for gibberellin (GA) biosynthesis and degradation by positively affecting the expression of the enzymes that convert GA9 into the bioactive GA4, as well as the enzymes involved in the degradation of GA4 (PubMed:28207974). {ECO:0000269|PubMed:16005292, ECO:0000269|PubMed:19401413, ECO:0000269|PubMed:22708996, ECO:0000269|PubMed:23741471, ECO:0000269|PubMed:28207974}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00350DAPTransfer from AT3G12720Download
Motif logo
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF0593980.0KF059398.1 Salvia miltiorrhiza MYB-related transcription factor (MYB44) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006352616.17e-96PREDICTED: myb-related protein 315-like
SwissprotQ8VZQ23e-69MYB61_ARATH; Transcription factor MYB61
TrEMBLA0A059PRE60.0A0A059PRE6_SALMI; MYB-related transcription factor
STRINGXP_009589329.11e-92(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA12242154
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G12720.11e-83myb domain protein 67
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Li C,Lu S
    Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors shows the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza.
    BMC Genomics, 2014. 15: p. 277
    [PMID:24725266]
  3. Matías-Hernández L, et al.
    AaMYB1 and its orthologue AtMYB61 affect terpene metabolism and trichome development in Artemisia annua and Arabidopsis thaliana.
    Plant J., 2017. 90(3): p. 520-534
    [PMID:28207974]