PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

SMil_00002684-RA_Salv

Organism

Salvia miltiorrhiza

Taxonomic ID

226208

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia

Family

HD-ZIP

Protein Properties

Length: 756aa MW: 83453.8 Da PI: 6.6302

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
SMil_00002684-RA_Salv	genome	NDCTCM	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	64.5	1.5e-20	99	154	1	56
TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 r+k +++t+ q++e+e+lF+++++p++++r eL+k+lgL rqVk+WFqNrR++ k SMil_00002684-RA_Salv 99 RKKYHRHTPRQIREMEALFKESPHPDEKQRLELSKQLGLHPRQVKFWFQNRRTQIK 154 7999************************************************9877 PP
2	START	191.6	3.9e-60	271	495	4	205
HHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS..........SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S. CS START 4 eeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv.........dsgealrasgvvdmvlallveellddkeqWdetla. 77 +aa+el k+a+ +ep+W +s+ +++n+de+++ f ++ +s+ea+r++++v+ +l+ lv++++d + qW+e ++ SMil_00002684-RA_Salv 271 SRAADELRKMASHGEPLWIRSYetgrDILNYDEYRKDFCAAEDhnstqprkkSSVEASRETALVFVDLPWLVQTFMDAN-QWKELFPc 357 57999******************************9665557799****************************.**** PP ...EEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEE CS START 78 ...kaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgilie 155 ka+t++vi++g ga +lm+ae q+l+plv+ R+++fvRy++q +a +w+i+dvSvd ++++ + s R++++pSg++ie SMil_00002684-RA_Salv 358 lisKAATVDVICNGegpngdGAAHLMFAEIQMLTPLVAtREVYFVRYSKQISANQWAIADVSVDGGEDRT-DTSPHRCRKRPSGCIIE 444 ******************************************************************.8999********* PP EECTCEEEE.EEEE-EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXX CS START 156 pksnghskv.twvehvdlkgrlphwllrslvksglaegaktwvatlqrqce 205 +ksngh+kv twvehv+++ +++h+l+r +v+sgl +gak+w++tlq+qc SMil_00002684-RA_Salv 445 DKSNGHCKVvTWVEHVECQRSTVHSLYRTIVNSGLGFGAKHWLSTLQQQCD 495 ****648*************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	5.1E-23	84	150	IPR009057	Homeodomain-like
SuperFamily	SSF46689	1.17E-20	89	157	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.783	96	156	IPR001356	Homeobox domain
SMART	SM00389	8.8E-19	98	160	IPR001356	Homeobox domain
Pfam	PF00046	5.8E-18	99	154	IPR001356	Homeobox domain
CDD	cd00086	2.00E-16	103	154	No hit	No description
PROSITE pattern	PS00027	0	131	154	IPR017970	Homeobox, conserved site
PROSITE profile	PS50848	36.316	259	499	IPR002913	START domain
SuperFamily	SSF55961	1.32E-30	262	496	No hit	No description
CDD	cd08875	6.99E-100	263	494	No hit	No description
SMART	SM00234	1.4E-54	268	496	IPR002913	START domain
Pfam	PF01852	5.5E-47	272	495	IPR002913	START domain
Gene3D	G3DSA:3.30.530.20	3.6E-4	312	494	IPR023393	START-like domain
SuperFamily	SSF55961	3.98E-12	526	719	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009957	Biological Process	epidermal cell fate specification
GO:0010062	Biological Process	negative regulation of trichoblast fate specification
GO:0005634	Cellular Component	nucleus
GO:0008289	Molecular Function	lipid binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 756 aa Download sequence Send to blast
LANAMSVDMS SNLPPSQPRD LFASAPALSL SLAGIFQGGG GEVEEGEGGI GGDAVEISSE 60 NSGAGKSRSD DDYELAAEGL MDDEDEDEND GGGGKKRKRK KYHRHTPRQI REMEALFKES 120 PHPDEKQRLE LSKQLGLHPR QVKFWFQNRR TQIKAIQERH ENSLLKSEID KLRDENKALR 180 ESIKTQSCLN KDAAAAAATT TEGQKLRLEN ARLKAEVEKL KSVIGKHPHA HGTSPRSSSH 240 SSGNDQENRS SFELFAANSG LEKARIMEAV SRAADELRKM ASHGEPLWIR SYETGRDILN 300 YDEYRKDFCA AEDHNSTQPR KKSSVEASRE TALVFVDLPW LVQTFMDANQ WKELFPCLIS 360 KAATVDVICN GEGPNGDGAA HLMFAEIQML TPLVATREVY FVRYSKQISA NQWAIADVSV 420 DGGEDRTDTS PHRCRKRPSG CIIEDKSNGH CKVVTWVEHV ECQRSTVHSL YRTIVNSGLG 480 FGAKHWLSTL QQQCDRLVFL VATNVPVKDS SGVATLAGRK SILKLAQRMS RSFCRALGDS 540 SFNSWNKITS KTGEEIRVAT RKNHNDPGEP LGTILSAVAS VWLPVPHHVL FDFLRDENRR 600 NEWDIMSKGS TVQTIANLAK GQDRGNAVTT MAMQNEEHKM WVLQDSSTNA YESMIIYAPV 660 DIKGMQSVIT GCDSSNIAVL PSGFSILPDG IESRPLVITS RPEEKSAEGG SLLTMAFQIL 720 ISNASATKLS LDSVESVNIL ISCTLQNIKT TLQCED

Sequence ? help Back to Top

Protein Sequence Length: 756 aa Download sequence Send to blast

LANAMSVDMS SNLPPSQPRD LFASAPALSL SLAGIFQGGG GEVEEGEGGI GGDAVEISSE  60
NSGAGKSRSD DDYELAAEGL MDDEDEDEND GGGGKKRKRK KYHRHTPRQI REMEALFKES  120
PHPDEKQRLE LSKQLGLHPR QVKFWFQNRR TQIKAIQERH ENSLLKSEID KLRDENKALR  180
ESIKTQSCLN KDAAAAAATT TEGQKLRLEN ARLKAEVEKL KSVIGKHPHA HGTSPRSSSH  240
SSGNDQENRS SFELFAANSG LEKARIMEAV SRAADELRKM ASHGEPLWIR SYETGRDILN  300
YDEYRKDFCA AEDHNSTQPR KKSSVEASRE TALVFVDLPW LVQTFMDANQ WKELFPCLIS  360
KAATVDVICN GEGPNGDGAA HLMFAEIQML TPLVATREVY FVRYSKQISA NQWAIADVSV  420
DGGEDRTDTS PHRCRKRPSG CIIEDKSNGH CKVVTWVEHV ECQRSTVHSL YRTIVNSGLG  480
FGAKHWLSTL QQQCDRLVFL VATNVPVKDS SGVATLAGRK SILKLAQRMS RSFCRALGDS  540
SFNSWNKITS KTGEEIRVAT RKNHNDPGEP LGTILSAVAS VWLPVPHHVL FDFLRDENRR  600
NEWDIMSKGS TVQTIANLAK GQDRGNAVTT MAMQNEEHKM WVLQDSSTNA YESMIIYAPV  660
DIKGMQSVIT GCDSSNIAVL PSGFSILPDG IESRPLVITS RPEEKSAEGG SLLTMAFQIL  720
ISNASATKLS LDSVESVNIL ISCTLQNIKT TLQCED

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	94	99	KKRKRK
2	94	100	KKRKRKK
3	96	100	RKRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. {ECO:0000269\|PubMed:11844112}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by GEM. {ECO:0000269\|PubMed:17450124}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011072373.1	0.0	homeobox-leucine zipper protein GLABRA 2 isoform X1
Swissprot	P46607	0.0	HGL2_ARATH; Homeobox-leucine zipper protein GLABRA 2
TrEMBL	A0A4D9B6H2	0.0	A0A4D9B6H2_SALSN; Homeobox-leucine zipper protein
STRING	VIT_09s0002g04340.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA6228	23	28

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79840.1	0.0	HD-ZIP family protein

Publications ? help Back to Top
Wu R,Citovsky V Adaptor proteins GIR1 and GIR2. I. Interaction with the repressor GLABRA2 and regulation of root hair development. Biochem. Biophys. Res. Commun., 2017. 488(3): p. 547-553 [PMID:28526410]