PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SMil_00002232-RA_Salv
Common NameMYB10
Organism
Salvia miltiorrhiza
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lamiaceae; Nepetoideae; Mentheae; Salvia
Family MYB
Protein Properties Length: 319aa    MW: 35692.7 Da    PI: 6.3989
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SMil_00002232-RA_SalvgenomeNDCTCMView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding50.35.3e-161462148
                           TSSS-HHHHHHHHHHHHHTTTT.-HHHHHHHHTTTS-HHHHHHHHHHHT CS
        Myb_DNA-binding  1 rgrWTteEdellvdavkqlGgg.tWktIartmgkgRtlkqcksrwqkyl 48
                           +g+W++eEd +l+ +++ +G+g +W + ++++g++R++k+c++rw++yl
  SMil_00002232-RA_Salv 14 KGPWSPEEDAKLKAYIETYGTGgNWIALPQKIGLKRCGKSCRLRWLNYL 62
                           79*********************************************97 PP
2Myb_DNA-binding39.11.7e-1269111246
                            SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
        Myb_DNA-binding   2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                            g +T+eEd ++  +    G++ W+ Ia+ ++ gRt++++k++w++
  SMil_00002232-RA_Salv  69 GGFTEEEDNIICSLYISIGSR-WSIIAAQLP-GRTDNDIKNYWNT 111
                            569******************.*********.***********97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129414.029962IPR017930Myb domain
SuperFamilySSF466894.9E-2711109IPR009057Homeodomain-like
SMARTSM007176.6E-131364IPR001005SANT/Myb domain
PfamPF002495.0E-151462IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.5E-251569IPR009057Homeodomain-like
CDDcd001672.10E-91662No hitNo description
PROSITE profilePS5129422.10963117IPR017930Myb domain
SMARTSM007172.3E-1167115IPR001005SANT/Myb domain
PfamPF002495.0E-1169111IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.609.9E-2470117IPR009057Homeodomain-like
CDDcd001673.72E-871113No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0035987Biological Processendodermal cell differentiation
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000021Biological Processregulation of ion homeostasis
GO:2000067Biological Processregulation of root morphogenesis
GO:0048226Cellular ComponentCasparian strip
GO:0000975Molecular Functionregulatory region DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 319 aa     Download sequence    Send to blast
MGRAPCCDKA NVKKGPWSPE EDAKLKAYIE TYGTGGNWIA LPQKIGLKRC GKSCRLRWLN  60
YLRPNIKHGG FTEEEDNIIC SLYISIGSRW SIIAAQLPGR TDNDIKNYWN TRLKKKLLGR  120
RKQSSTNRMR IAGQETKDGN EEASLQNLSS SAMERLQLHM QLQNPFSFYN NPALWPKMIQ  180
SHDHSQIQNQ NALIDSQPPP ADQNYSNLKD DQVEIGCVNG FSSSESSFAL NGGEGSSLVE  240
QNGGIEMNTS GFTHAELDDL LNDRSSSFLA EEMDASKGNN QAWWPNEFAA GSTLFNSWGS  300
TSLVHDANFQ DYVIGYNMH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A2e-25141177108B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factors that activates genes required for endodermal differentiation but represses genes involved in proliferative divisions, thus regulating the transition from proliferation to differentiation in root endodermis (PubMed:26371322). Required for Casparian strip formation by positively regulating the expression of the Casparian strip genes CASP1, PER64 and ESB1 and other endodermis-specific genes, thus triggering correct localized lignin biosynthesis in root endodermis and subsequently regulating global ion homeostasis (PubMed:26124109, PubMed:26371322). {ECO:0000269|PubMed:26124109, ECO:0000269|PubMed:26371322}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Directly up-regulated by SCARECROW (SCR), as part of the differentiation program controlled by SHORT-ROOT (SHR). {ECO:0000269|PubMed:24517883, ECO:0000269|PubMed:26371322}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF0593640.0KF059364.1 Salvia miltiorrhiza MYB-related transcription factor (MYB10) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011070175.11e-136transcription factor MYB36-like
SwissprotQ9FKL29e-99MYB36_ARATH; Transcription factor MYB36
TrEMBLU5KKB10.0U5KKB1_SALMI; MYB-like protein 1
STRINGEOY317641e-118(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA12242154
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G57620.18e-93myb domain protein 36
Publications ? help Back to Top
  1. Li C,Lu S
    Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors shows the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza.
    BMC Genomics, 2014. 15: p. 277
    [PMID:24725266]
  2. Fernández-Marcos M, et al.
    Control of Arabidopsis lateral root primordium boundaries by MYB36.
    New Phytol., 2017. 213(1): p. 105-112
    [PMID:27891649]