PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sme2.5_09817.1_g00003.1

Organism

Solanum melongena

Taxonomic ID

4111

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

C2H2

Protein Properties

Length: 536aa MW: 60043.1 Da PI: 6.0996

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sme2.5_09817.1_g00003.1	genome	EGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21	9e-07	284	305	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H Sme2.5_09817.1_g00003.1 284 FCTICGKGFKRDANLRMHMRGH 305 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.5E-5	281	308	No hit	No description
PROSITE profile	PS50157	12.03	283	310	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0026	283	305	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.1E-5	284	320	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	285	305	IPR007087	Zinc finger, C2H2
SMART	SM00355	65	332	365	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	25	370	392	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 536 aa Download sequence Send to blast
MLVEVLLFFF VLLLPREADS DMDPDDSLSE DAWIKSSSSD NELLKIMPSD NHSFTNLNLH 60 AQKWEGSSYL DQQIRIEQQF SGITKPKHTY EMDQQRNQWN ENHDTTRIND WDPRALLNNL 120 SFLEQKVHQL QELVHLIVGR RGQDGVQGND LIVQQQQLIT ADLTSIIVQL ISTAGSLLPT 180 MKHTLSSAIP AASQFGQVGG VTGPSTTGTS AGGLTCSNDS VAKVEDQSNH IDQLRDCGIE 240 QNHAVDEHEL KDEDEAEEEE NLPPGSYEIL QLEKEEILAP HTHFCTICGK GFKRDANLRM 300 HMRGHGDEYK TPAALAKPHK EPSSEPTLIK RYSCPFVGCK RNKEHKKFQP LKTILCVKNH 360 YKRTHCEKAY TCSRCNIKKF SVIADLKTHE KHCGKDKWLC SCGTTFSRKD KLFGHISLFQ 420 GHTPAISPDE TKGSAAGTSD RGQTSEVTMK ALQENYKVNA SNGNEFQNPG VVKEGAYSPS 480 SYFSPLNFDT SNLNGFQEFP RPPFDESDSS FSFLLSGSCE YPPHKAAKFM SSTEME

Sequence ? help Back to Top

Protein Sequence Length: 536 aa Download sequence Send to blast

MLVEVLLFFF VLLLPREADS DMDPDDSLSE DAWIKSSSSD NELLKIMPSD NHSFTNLNLH  60
AQKWEGSSYL DQQIRIEQQF SGITKPKHTY EMDQQRNQWN ENHDTTRIND WDPRALLNNL  120
SFLEQKVHQL QELVHLIVGR RGQDGVQGND LIVQQQQLIT ADLTSIIVQL ISTAGSLLPT  180
MKHTLSSAIP AASQFGQVGG VTGPSTTGTS AGGLTCSNDS VAKVEDQSNH IDQLRDCGIE  240
QNHAVDEHEL KDEDEAEEEE NLPPGSYEIL QLEKEEILAP HTHFCTICGK GFKRDANLRM  300
HMRGHGDEYK TPAALAKPHK EPSSEPTLIK RYSCPFVGCK RNKEHKKFQP LKTILCVKNH  360
YKRTHCEKAY TCSRCNIKKF SVIADLKTHE KHCGKDKWLC SCGTTFSRKD KLFGHISLFQ  420
GHTPAISPDE TKGSAAGTSD RGQTSEVTMK ALQENYKVNA SNGNEFQNPG VVKEGAYSPS  480
SYFSPLNFDT SNLNGFQEFP RPPFDESDSS FSFLLSGSCE YPPHKAAKFM SSTEME

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975523	0.0	HG975523.1 Solanum lycopersicum chromosome ch11, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015058711.1	0.0	protein SENSITIVE TO PROTON RHIZOTOXICITY 1
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A2G2ZP06	0.0	A0A2G2ZP06_CAPAN; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
STRING	PGSC0003DMT400023881	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4754	24	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	1e-170	C2H2 family protein

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]