PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sme2.5_08092.1_g00001.1

Organism

Solanum melongena

Taxonomic ID

4111

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

WRKY

Protein Properties

Length: 505aa MW: 55811.9 Da PI: 7.0493

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sme2.5_08092.1_g00001.1	genome	EGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.3	4.2e-30	228	287	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+ +d +++++tYeg+Hnh+ Sme2.5_08092.1_g00001.1 228 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCIQDMSILITTYEGTHNHP 287 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	4.5E-31	214	289	IPR003657	WRKY domain
SuperFamily	SSF118290	3.27E-27	220	289	IPR003657	WRKY domain
PROSITE profile	PS50811	28.242	223	289	IPR003657	WRKY domain
SMART	SM00774	7.2E-36	228	288	IPR003657	WRKY domain
Pfam	PF03106	1.4E-26	229	287	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 505 aa Download sequence Send to blast
MDAVFRKSIR GGVVLKEDTK IKADHEEDDI NCLKVGKGRK SVHHEDDNSK SSQQKDLEED 60 DQLESAKADM EVVKEENQRL KKHLDRIMKD YRNLQMQFQE VAQKTNGVKH DEAELVSLSL 120 GRTSSDTKKE LYKLILSKNE NEEEEDNLAL GLDCNFQWHA ITPSKSSPSN LSPENSSGEV 180 KDDEKGAETW PPQKVLKTMR NEEDDVAQQN PTKRAKVSVR VRCDTPTMND GCQWRKYGQK 240 IAKGNPCPRA YYRCTVAPSC PVRKQVQRCI QDMSILITTY EGTHNHPLPQ SATSMAFTTS 300 AAASMLLSGS SSSGSGPTST TGSATSTALN HYLSYNSKPN PFYLPNSSIS SSSHSQYPTI 360 TLDLTSGSSI SSLPVHNHRM SSNYPPRYNN SSTNILNFSS YDSNMSWSNG NFNQASQSYL 420 QSNIISAMQP TQTNLSPQDT ITAATKAIAS DPKFQSALAV ALTSIIGSRG ANHHIDEKSE 480 QNLKVNQPFP VLCSLPSTSH GDYKD

Sequence ? help Back to Top

Protein Sequence Length: 505 aa Download sequence Send to blast

MDAVFRKSIR GGVVLKEDTK IKADHEEDDI NCLKVGKGRK SVHHEDDNSK SSQQKDLEED  60
DQLESAKADM EVVKEENQRL KKHLDRIMKD YRNLQMQFQE VAQKTNGVKH DEAELVSLSL  120
GRTSSDTKKE LYKLILSKNE NEEEEDNLAL GLDCNFQWHA ITPSKSSPSN LSPENSSGEV  180
KDDEKGAETW PPQKVLKTMR NEEDDVAQQN PTKRAKVSVR VRCDTPTMND GCQWRKYGQK  240
IAKGNPCPRA YYRCTVAPSC PVRKQVQRCI QDMSILITTY EGTHNHPLPQ SATSMAFTTS  300
AAASMLLSGS SSSGSGPTST TGSATSTALN HYLSYNSKPN PFYLPNSSIS SSSHSQYPTI  360
TLDLTSGSSI SSLPVHNHRM SSNYPPRYNN SSTNILNFSS YDSNMSWSNG NFNQASQSYL  420
QSNIISAMQP TQTNLSPQDT ITAATKAIAS DPKFQSALAV ALTSIIGSRG ANHHIDEKSE  480
QNLKVNQPFP VLCSLPSTSH GDYKD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	9e-21	228	289	17	77	Probable WRKY transcription factor 4
2lex_A	9e-21	228	289	17	77	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	GU017421	0.0	GU017421.1 Solanum lycopersicum WRKY72 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001234802.2	0.0	WRKY transcription factor 72a
Swissprot	A0A3Q7GFB5	0.0	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	M1BJA0	0.0	M1BJA0_SOLTU; Uncharacterized protein
STRING	Solyc03g113120.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	2e-58	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]