PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sme2.5_00125.1_g00017.1

Organism

Solanum melongena

Taxonomic ID

4111

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum

Family

ERF

Protein Properties

Length: 796aa MW: 88626.6 Da PI: 5.8751

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sme2.5_00125.1_g00017.1	genome	EGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.4	1e-19	633	682	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+W+AeIrdp+ + +r++lg+f+tae+Aa a+++a+++++g Sme2.5_00125.1_g00017.1 633 RYRGVRQRP-WGKWAAEIRDPV----KaARVWLGTFDTAEGAALAYDEAALRFKG 682 7******.******64....55**********************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd04048	6.51E-31	1	103	No hit	No description
SuperFamily	SSF49562	2.24E-9	9	105	IPR000008	C2 domain
Gene3D	G3DSA:2.60.40.150	8.0E-10	10	95	IPR000008	C2 domain
Pfam	PF00168	1.8E-7	15	91	IPR000008	C2 domain
Gene3D	G3DSA:2.60.40.150	4.2E-5	107	178	IPR000008	C2 domain
SuperFamily	SSF49562	8.79E-6	126	178	IPR000008	C2 domain
Pfam	PF00168	0.5	131	178	IPR000008	C2 domain
CDD	cd01459	2.12E-111	260	499	No hit	No description
SuperFamily	SSF53300	1.04E-14	288	487	IPR002035	von Willebrand factor, type A
SMART	SM00327	1.2E-7	289	491	IPR002035	von Willebrand factor, type A
Pfam	PF07002	4.1E-73	310	504	IPR010734	Copine
Pfam	PF00847	8.9E-13	633	682	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.79	633	690	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.2E-31	633	691	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.58E-21	633	691	IPR016177	DNA-binding domain
SMART	SM00380	2.1E-36	633	696	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.5E-10	634	645	IPR001471	AP2/ERF domain
CDD	cd00018	1.88E-25	641	691	No hit	No description
PRINTS	PR00367	1.5E-10	656	672	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009266	Biological Process	response to temperature stimulus
GO:0009270	Biological Process	response to humidity
GO:0019725	Biological Process	cellular homeostasis
GO:0045793	Biological Process	positive regulation of cell size
GO:0060548	Biological Process	negative regulation of cell death
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0005515	Molecular Function	protein binding
GO:0005544	Molecular Function	calcium-dependent phospholipid binding

Sequence ? help Back to Top
Protein Sequence Length: 796 aa Download sequence Send to blast
MAVLYSKEKD GSLKELSRTE VVLNSLNPKW ITKYTMAYYF ETVQNLVFRV YDVDTQFHNQ 60 DVKMLKLEDQ DFLGEASCTL AQIVAKSGRS LTMDLVCGEQ SSGQAHAKKF GKLTVFAEES 120 VSSKTTVELK LRCSELESKD LFSKSDPFLV VSKTTESGII VPICKTEVIQ NDHSPNWKPV 180 ILNIQQIGSK KSSDTLDGWY VALHNVYNNN NNIPSRIPQV GSGKGRIKIQ KSLLDLEKLH 240 SAGTGASLFI PTAMGPKQEN KVLKSQLFVE SYSEKIQYTF LDYLASGYEL NFMVAIDFTA 300 SNGNPRLPDS LHYIDPSGRP NAYQRAILDV GEVLQFYDTD KRFPAWGFGA RPIDGPVSHC 360 FNLNGSSTYC EVEGIQGIMT AYISALHNVS LAGPTLFGPV ITSAAHIASQ SLTNIERKYF 420 VLLIITDGVI TDLQETKDAL VQAADLPLSI MIVGVGGADF KEMEILDADK GERLESTTGR 480 VAVRDIVQFV PLRDVQSRSH IINFSVNKLL DAEKDNQTSS RALPRRCSFP VIDYFATSDA 540 KIAVLFKAIE EMRRSGSNER ERKGIYPTYS TTRSEQDMSA MVSALSQVIG NSSAVDDAVH 600 VNPLTLIPQS STALEQNQSQ SSIQDQGNTA RRRYRGVRQR PWGKWAAEIR DPVKAARVWL 660 GTFDTAEGAA LAYDEAALRF KGNKAKLNFP ERVQGQFHYL TPDQHAATSS NTIDPYNSQQ 720 QQQSYPDVHH YADLLLRSDD NIDLNFDVSP STCYQYGSSF EVSQSFEQQQ VSTSHNEDEE 780 EKQDFMKFPG SHFGNS

Sequence ? help Back to Top

Protein Sequence Length: 796 aa Download sequence Send to blast

MAVLYSKEKD GSLKELSRTE VVLNSLNPKW ITKYTMAYYF ETVQNLVFRV YDVDTQFHNQ  60
DVKMLKLEDQ DFLGEASCTL AQIVAKSGRS LTMDLVCGEQ SSGQAHAKKF GKLTVFAEES  120
VSSKTTVELK LRCSELESKD LFSKSDPFLV VSKTTESGII VPICKTEVIQ NDHSPNWKPV  180
ILNIQQIGSK KSSDTLDGWY VALHNVYNNN NNIPSRIPQV GSGKGRIKIQ KSLLDLEKLH  240
SAGTGASLFI PTAMGPKQEN KVLKSQLFVE SYSEKIQYTF LDYLASGYEL NFMVAIDFTA  300
SNGNPRLPDS LHYIDPSGRP NAYQRAILDV GEVLQFYDTD KRFPAWGFGA RPIDGPVSHC  360
FNLNGSSTYC EVEGIQGIMT AYISALHNVS LAGPTLFGPV ITSAAHIASQ SLTNIERKYF  420
VLLIITDGVI TDLQETKDAL VQAADLPLSI MIVGVGGADF KEMEILDADK GERLESTTGR  480
VAVRDIVQFV PLRDVQSRSH IINFSVNKLL DAEKDNQTSS RALPRRCSFP VIDYFATSDA  540
KIAVLFKAIE EMRRSGSNER ERKGIYPTYS TTRSEQDMSA MVSALSQVIG NSSAVDDAVH  600
VNPLTLIPQS STALEQNQSQ SSIQDQGNTA RRRYRGVRQR PWGKWAAEIR DPVKAARVWL  660
GTFDTAEGAA LAYDEAALRF KGNKAKLNFP ERVQGQFHYL TPDQHAATSS NTIDPYNSQQ  720
QQQSYPDVHH YADLLLRSDD NIDLNFDVSP STCYQYGSSF EVSQSFEQQQ VSTSHNEDEE  780
EKQDFMKFPG SHFGNS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	5e-26	632	693	1	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of cell death and defense responses. Negative regulator of several R genes, including SNC1. May have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane at low temperature. Exhibits calcium-dependent phospholipid binding properties. {ECO:0000269\|PubMed:15031411, ECO:0000269\|PubMed:16367962, ECO:0000269\|PubMed:18855102, ECO:0000269\|PubMed:19522566, ECO:0000269\|PubMed:20634289}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by high temperature. Up-regulated by pathogen, calcium, low humidity, avirulence gene product avrRpt2 and salicylic acid. {ECO:0000269\|PubMed:11544183, ECO:0000269\|PubMed:12857819, ECO:0000269\|PubMed:18855102}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975442	2e-68	HG975442.1 Solanum pennellii chromosome ch03, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006341473.1	0.0	PREDICTED: protein BONZAI 1-like isoform X2
Swissprot	Q941L3	0.0	BON1_ARATH; Protein BONZAI 1
TrEMBL	A0A0V0IGX2	0.0	A0A0V0IGX2_SOLCH; Uncharacterized protein
STRING	Solyc03g118200.2.1	0.0	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1973	2	2

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G61890.1	3e-36	ERF family protein

Publications ? help Back to Top
Abel S, et al. Arabidopsis Research 2000. Plant Cell, 2000. 12(12): p. 2302-2308 [PMID:11148279] Hua J,Grisafi P,Cheng SH,Fink GR Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes. Genes Dev., 2001. 15(17): p. 2263-72 [PMID:11544183] Jambunathan N,Siani JM,McNellis TW A humidity-sensitive Arabidopsis copine mutant exhibits precocious cell death and increased disease resistance. Plant Cell, 2001. 13(10): p. 2225-40 [PMID:11595798] Yang S,Hua J A haplotype-specific Resistance gene regulated by BONZAI1 mediates temperature-dependent growth control in Arabidopsis. Plant Cell, 2004. 16(4): p. 1060-71 [PMID:15031411] Fatland BL,Nikolau BJ,Wurtele ES Reverse genetic characterization of cytosolic acetyl-CoA generation by ATP-citrate lyase in Arabidopsis. Plant Cell, 2005. 17(1): p. 182-203 [PMID:15608338] Liu J,Jambunathan N,McNellis TW Transgenic expression of the von Willebrand A domain of the BONZAI 1/COPINE 1 protein triggers a lesion-mimic phenotype in Arabidopsis. Planta, 2005. 221(1): p. 85-94 [PMID:15843967] Yang S, et al. The BON/CPN gene family represses cell death and promotes cell growth in Arabidopsis. Plant J., 2006. 45(2): p. 166-79 [PMID:16367962] Yang H,Li Y,Hua J The C2 domain protein BAP1 negatively regulates defense responses in Arabidopsis. Plant J., 2006. 48(2): p. 238-48 [PMID:17018034] Yang H,Yang S,Li Y,Hua J The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death. Plant Physiol., 2007. 145(1): p. 135-46 [PMID:17631528] Li Y,Yang S,Yang H,Hua J The TIR-NB-LRR gene SNC1 is regulated at the transcript level by multiple factors. Mol. Plant Microbe Interact., 2007. 20(11): p. 1449-56 [PMID:17977156] Lee TF,McNellis TW Evidence that the BONZAI1/COPINE1 protein is a calcium- and pathogen-responsive defense suppressor. Plant Mol. Biol., 2009. 69(1-2): p. 155-66 [PMID:18855102] Li Y,Pennington BO,Hua J Multiple R-like genes are negatively regulated by BON1 and BON3 in arabidopsis. Mol. Plant Microbe Interact., 2009. 22(7): p. 840-8 [PMID:19522566] Li Y,Gou M,Sun Q,Hua J Requirement of calcium binding, myristoylation, and protein-protein interaction for the Copine BON1 function in Arabidopsis. J. Biol. Chem., 2010. 285(39): p. 29884-91 [PMID:20634289] Wang Z,Meng P,Zhang X,Ren D,Yang S BON1 interacts with the protein kinases BIR1 and BAK1 in modulation of temperature-dependent plant growth and cell death in Arabidopsis. Plant J., 2011. 67(6): p. 1081-93 [PMID:21623975] Bao Z,Yang H,Hua J Perturbation of cell cycle regulation triggers plant immune response via activation of disease resistance genes. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(6): p. 2407-12 [PMID:23345424] Zou B,Yang DL,Shi Z,Dong H,Hua J Monoubiquitination of histone 2B at the disease resistance gene locus regulates its expression and impacts immune responses in Arabidopsis. Plant Physiol., 2014. 165(1): p. 309-18 [PMID:24664204] Gou M, et al. Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2304-23 [PMID:26408532] Meng Z,Ruberti C,Gong Z,Brandizzi F CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses. Plant J., 2017. 89(3): p. 486-501 [PMID:27747970] Yang DL, et al. Calcium Pumps and Interacting BON1 Protein Modulate Calcium Signature, Stomatal Closure, and Plant Immunity. Plant Physiol., 2017. 175(1): p. 424-437 [PMID:28701352] Yin X, et al. Rice copine genes OsBON1 and OsBON3 function as suppressors of broad-spectrum disease resistance. Plant Biotechnol. J., 2018. 16(8): p. 1476-1487 [PMID:29356349]