PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Solyc06g072310.2.1
Common NameLOC101246729
Organism
Solanum lycopersicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family HD-ZIP
Protein Properties Length: 718aa    MW: 78653.3 Da    PI: 6.6208
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Solyc06g072310.2.1genomeITAGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.41.2e-183586556
                        SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
            Homeobox  5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                        +++t++q++ Le++F+++++p+++ r +L++ lgL  rq+k+WFqNrR++ k
  Solyc06g072310.2.1 35 HRHTAHQIQSLESVFKECPHPDEKIRLQLSRDLGLAPRQIKFWFQNRRTQLK 86
                        689*********************************************9987 PP
2START171.36.5e-542284532206
                         HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....E CS
               START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....k 78 
                         +a  a++el+++ + +ep+W+ks     + ++ d++ q+f+++++       ++ea+r sgvv+m+   lv  ++d++ +W e ++    k
  Solyc06g072310.2.1 228 IAGNAMEELIRLLQTNEPLWTKSTtdgrDVLDIDKYGQIFPKANSslknpnVRVEASRQSGVVIMNGLALVDMFMDVN-KWVEFFPtivsK 317
                         67899**********************99***********99999*********************************.************ PP

                         EEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEE CS
               START  79 aetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghs 162
                         a tlevis g      ++lqlm+ae q+lsplvp R  +f+R+++q + g+w+ivdvS d +q++   +s+ ++++lpSg+li++++ng+s
  Solyc06g072310.2.1 318 ARTLEVISCGmmgsrsSTLQLMYAEQQVLSPLVPtRQLYFLRFCQQIETGSWAIVDVSYDITQENMYPPSSCKVHKLPSGCLIQDMPNGYS 408
                         ***************************************************************998899********************** PP

                         EEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
               START 163 kvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                         kvtw+ehv+++++   h l+r l+ sg+a+ga +w+  lqr+ce+
  Solyc06g072310.2.1 409 KVTWLEHVEVEEKGSiHRLYRDLIFSGMAFGAERWLGSLQRLCER 453
                         **********998666***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.09E-181588IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.8E-201782IPR009057Homeodomain-like
PROSITE profilePS5007117.1672888IPR001356Homeobox domain
SMARTSM003892.1E-182992IPR001356Homeobox domain
CDDcd000861.26E-173089No hitNo description
PfamPF000462.8E-163586IPR001356Homeobox domain
PROSITE patternPS0002706386IPR017970Homeobox, conserved site
PROSITE profilePS5084848.053218456IPR002913START domain
SuperFamilySSF559611.24E-35219455No hitNo description
CDDcd088753.58E-112222452No hitNo description
SMARTSM002342.0E-43227453IPR002913START domain
PfamPF018528.4E-46228453IPR002913START domain
Gene3DG3DSA:3.30.530.204.4E-5233263IPR023393START-like domain
Gene3DG3DSA:3.30.530.204.4E-5336426IPR023393START-like domain
SuperFamilySSF559611.31E-20474683No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 718 aa     Download sequence    Send to blast
MEYGGGGGGG GGGGGASSSG GGDATDASRK KKRFHRHTAH QIQSLESVFK ECPHPDEKIR  60
LQLSRDLGLA PRQIKFWFQN RRTQLKSQHE RADNSALRSE NDRIRCENIA IREAIKNVIC  120
PSCGGPPVTE DTYFDEQKLR MENLQLKEEL DKISSIAAKY MGRPISQLPP VQPVHLSSLN  180
LMSMPNFGLT GPSLDLDLLP GSSTSTYPNL PCPTFNISDM DKSLMADIAG NAMEELIRLL  240
QTNEPLWTKS TTDGRDVLDI DKYGQIFPKA NSSLKNPNVR VEASRQSGVV IMNGLALVDM  300
FMDVNKWVEF FPTIVSKART LEVISCGMMG SRSSTLQLMY AEQQVLSPLV PTRQLYFLRF  360
CQQIETGSWA IVDVSYDITQ ENMYPPSSCK VHKLPSGCLI QDMPNGYSKV TWLEHVEVEE  420
KGSIHRLYRD LIFSGMAFGA ERWLGSLQRL CERYACLMVS GNSSRELGGV IPSPEGKKSM  480
MKVAERMVSS FCASINPSNG HQWNNISTLD EFEVRATLQK CTDPGQPNGV VISAASTIWL  540
PVPPQHVFNF LRDERTRPQW DVLSNQNPVQ EVAHIANGSH PGNSISVLRA YNTSQNNMLI  600
LQESCIDSSG SLVVYSPVDL QSINIAMSGE DTTYIPLLPS GFTISPDGRG SDEALSMNNG  660
STMRAGGGGS LVTVVFQILV SSLSSSAKMS PESVNTVNNL IGNTIHQIKA ALNCSTS*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: During embryo development, expressed in all cells at the 4- and 16-cell embryo stages. Expression is restricted to the protoderm from the globular stage onward. {ECO:0000269|PubMed:25564655}.
UniprotTISSUE SPECIFICITY: Expressed in apical meristems and young epidermal tissue including trichomes and stipules. Expressed in lateral root tips, the L1 layer of apical inflorescence meristems and early flower primordia, carpel and petal epidermis, stigma papillae, ovule primordia, nucellus and embryo. {ECO:0000269|PubMed:16778018}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapSolyc06g072310.2.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004241474.10.0homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A3Q7H1K20.0A0A3Q7H1K2_SOLLC; Uncharacterized protein
STRINGSolyc06g072310.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Representative plantOGRP14515136
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments.
    Theor. Appl. Genet., 2005. 112(1): p. 72-84
    [PMID:16208505]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  4. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  5. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  6. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  7. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  8. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  9. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  10. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  11. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]