PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Solyc05g051200.1.1

Organism

Solanum lycopersicum

Taxonomic ID

4081

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon

Family

ERF

Protein Properties

Length: 225aa MW: 25528.5 Da PI: 5.1924

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Solyc05g051200.1.1	genome	ITAG	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	60.2	4.9e-19	96	146	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y GVr ++ +g++++eIrd + ng r++lg+f+taeeAa a+++a+++++g Solyc05g051200.1.1 96 HYIGVRKRP-WGKYASEIRDSTRNG--IRVWLGTFDTAEEAALAYDQAALSMRG 146 799****.******44465..***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	8.00E-28	95	154	No hit	No description
SMART	SM00380	1.4E-32	96	160	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.456	96	154	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	7.85E-22	96	156	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	9.1E-29	96	155	IPR001471	AP2/ERF domain
Pfam	PF00847	6.3E-13	96	146	IPR001471	AP2/ERF domain
PRINTS	PR00367	7.6E-10	97	108	IPR001471	AP2/ERF domain
PRINTS	PR00367	7.6E-10	120	136	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 225 aa Download sequence Send to blast
MSSPLEIDTS FSHSNLLFLE DESSWSNTHD PFVDIDEYLP IIIPCNDEEI VVESSNTSTT 60 TTTTTTSKVA SIQNIHHDQE EVTSIEKKHE DDQEKHYIGV RKRPWGKYAS EIRDSTRNGI 120 RVWLGTFDTA EEAALAYDQA ALSMRGPWSL LNFPMEHVKK SLENIEYSCK DGLSPAAVLK 180 ATHKTRRVKH KRSSRKKKNE NLENVFVFQD LGVELLEELL MTSS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	9e-29	95	155	1	61	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	1e-28	95	155	4	64	ATERF1
3gcc_A	1e-28	95	155	4	64	ATERF1
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Les.3679	0.0	callus\| fruit\| leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269\|PubMed:11950980}.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression during the plant development, and/or mediated by stress factors and by components of stress signal transduction pathways. Seems to be a key integrator of ethylene and jasmonate signals in the regulation of ethylene/jasmonate-dependent defenses. Can mediate resistance to necrotizing fungi (Botrytis cinerea and Plectosphaerella cucumerina) and to soil borne fungi (Fusarium oxysporum conglutinans and Fusiarium oxysporum lycopersici), but probably not to necrotizing bacteria (Pseudomonas syringae tomato). {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Function -- GeneRIF ? help Back to Top
TERF1 is a multifunctional ERF protein that can integrate different stress signal pathways [PMID: 15871029] The transgenic plants were growing vigorously, had dark green leaves and showed no symptoms of salt damage implying that the JERFs gene enhanced their salt tolerance. [PMID: 19203952] these findings suggest that TERF1 is an ethylene inducible factor regulating reactive oxygen species scavenging during stress responses. [PMID: 27435661]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Solyc05g051200.1.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Ethylene induction is completely dependent on functional ETHYLENE-INSENSITIVE2 (EIN2), ETHYLENE-INSENSITIVE3 (EIN3), which is itself a transcription factor and CORONATIVE-INSENSITIVE1 (COI1) proteins. Induction by jasmonate, B.cinerea or F.oxysporum as well as the synergistic induction by ethylene and jasmonate requires EIN2 and COI1. Induction by methyl jasmonate (MeJA) is independent of JAR1. Induction by salicylic acid (SA) is dependent on NPR1 but not on PAD4. Seems not to be induced by Alternaria brassicicola. {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY044236	0.0	Lycopersicon esculentum ethylene-responsive factor 1 (ERF1) mRNA, complete cds
GenBank	EU395634	0.0	Solanum lycopersicum ethylene response factor (ERF1) gene, promoter region and complete cds

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001234841.2	1e-167	ethylene-responsive transcription factor 1
Swissprot	Q8LDC8	3e-48	ERF92_ARATH; Ethylene-responsive transcription factor 1B
TrEMBL	A0A3Q7GNC2	1e-165	A0A3Q7GNC2_SOLLC; Uncharacterized protein
STRING	Solyc05g051200.1.1	1e-166	(Solanum lycopersicum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165
Representative plant	OGRP6	16	1718

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	5e-34	ethylene response factor 1

Link Out ? help Back to Top
Phytozome	Solyc05g051200.1.1
Entrez Gene	606712

Publications ? help Back to Top
Huang Z, et al. Tomato TERF1 modulates ethylene response and enhances osmotic stress tolerance by activating expression of downstream genes. FEBS Lett., 2004. 573(1-3): p. 110-6 [PMID:15327984] Zhang X, et al. Expressing TERF1 in tobacco enhances drought tolerance and abscisic acid sensitivity during seedling development. Planta, 2005. 222(3): p. 494-501 [PMID:15871029] Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments. Theor. Appl. Genet., 2005. 112(1): p. 72-84 [PMID:16208505] Zarate SI,Kempema LA,Walling LL Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses. Plant Physiol., 2007. 143(2): p. 866-75 [PMID:17189328] Li Y, et al. Expression of jasmonic ethylene responsive factor gene in transgenic poplar tree leads to increased salt tolerance. Tree Physiol., 2009. 29(2): p. 273-9 [PMID:19203952] Vahabi K,Camehl I,Sherameti I,Oelmüller R Growth of Arabidopsis seedlings on high fungal doses of Piriformospora indica has little effect on plant performance, stress, and defense gene expression in spite of elevated jasmonic acid and jasmonic acid-isoleucine levels in the roots. Plant Signal Behav, 2013. 8(11): p. e26301 [PMID:24047645] Kim HG, et al. GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Plant Physiol., 2013. 163(4): p. 1776-91 [PMID:24170202] Li J,Jia H,Wang J cGMP and ethylene are involved in maintaining ion homeostasis under salt stress in Arabidopsis roots. Plant Cell Rep., 2014. 33(3): p. 447-59 [PMID:24306353] Zhong S, et al. Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20 [PMID:24599595] Kim HG, et al. GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis. FEBS Lett., 2014. 588(9): p. 1652-8 [PMID:24631536] Schellingen K, et al. Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression. BMC Plant Biol., 2014. 14: p. 214 [PMID:25082369] Ellouzi H, et al. A comparative study of the early osmotic, ionic, redox and hormonal signaling response in leaves and roots of two halophytes and a glycophyte to salinity. Planta, 2014. 240(6): p. 1299-317 [PMID:25156490] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Zhang H, et al. Ethylene Response Factor TERF1, Regulated by ETHYLENE-INSENSITIVE3-like Factors, Functions in Reactive Oxygen Species (ROS) Scavenging in Tobacco (Nicotiana tabacum L.). Sci Rep, 2016. 6: p. 29948 [PMID:27435661] Cheng MC,Kuo WC,Wang YM,Chen HY,Lin TP UBC18 mediates ERF1 degradation under light-dark cycles. New Phytol., 2017. 213(3): p. 1156-1167 [PMID:27787902] Timmermann T, et al. Paraburkholderia phytofirmans PsJN Protects Arabidopsis thaliana Against a Virulent Strain of Pseudomonas syringae Through the Activation of Induced Resistance. Mol. Plant Microbe Interact., 2017. 30(3): p. 215-230 [PMID:28118091] Yu Y,Huang R Integration of Ethylene and Light Signaling Affects Hypocotyl Growth in Arabidopsis. Front Plant Sci, 2017. 8: p. 57 [PMID:28174592] Lestari R, et al. Overexpression of Hevea brasiliensis ethylene response factor HbERF-IXc5 enhances growth and tolerance to abiotic stress and affects laticifer differentiation. Plant Biotechnol. J., 2018. 16(1): p. 322-336 [PMID:28626940] Dinolfo MI,Castañares E,Stenglein SA Resistance of Fusarium poae in Arabidopsis leaves requires mainly functional JA and ET signaling pathways. Fungal Biol, 2017. 121(10): p. 841-848 [PMID:28889908]