PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Seita.5G468700.5.p

Common Name

LOC101780320, SETIT_000591mg

Organism

Setaria italica

Taxonomic ID

4555

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

MYB_related

Protein Properties

Length: 662aa MW: 71847.5 Da PI: 9.5069

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Seita.5G468700.5.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	22.8	2.1e-07	562	611	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT...TTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg...kgRtlkqcksrwqky 47 r++++ E e lv+av+qlG+g+W+ + + +Rt ++k++w ++ Seita.5G468700.5.p 562 RMPFSVGEVEALVEAVEQLGTGRWRDVKMHAFdgaDHRTYVDLKDKWKTL 611 7899999******************9999899***********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54236	2.17E-7	368	444	IPR029071	Ubiquitin-related domain
PROSITE profile	PS50053	9.286	374	444	IPR000626	Ubiquitin domain
PROSITE profile	PS51294	15.733	557	616	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	4.1E-9	558	613	IPR009057	Homeodomain-like
SMART	SM00717	6.4E-7	561	614	IPR001005	SANT/Myb domain
CDD	cd11660	2.00E-16	564	613	No hit	No description
SuperFamily	SSF46689	9.37E-15	564	644	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0032204	Biological Process	regulation of telomere maintenance
GO:0042162	Molecular Function	telomeric DNA binding
GO:0042803	Molecular Function	protein homodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 662 aa Download sequence Send to blast
MVSQKRLGYG SRGRQIPAMP RVPNSVRGKR TTRRKKNEMC AFDLLASVAG TLLTDQDSSS 60 YVPNTSGAAT SYARNRKSVK EEYFDEILHL KNVAVKKDCG SGCVVGSGGV SALPRKGNDG 120 LAENSLTRNE DESVLKSLTV KSNMLARDSS VRCTRPCEIS RGLGIICEYG AFGVFHPGSS 180 SSAEAGQAHQ AEPKVIRSKA DGHTAALDSL FDSVDLDGRP PALVSSDSSS GVLLCSHDKE 240 HKAASLCQVE MQHTADRDDD ENSSGCTHPS TTGNEGYKPH FLGNHRIRKL LASKVRKAAR 300 NKTSGGMSSK GSKLNFCGKK IPTTRQKVQR TNFKRKKLAR GTTPFAKGML TGATGTSFRM 360 QGQNKSCGSE DYHVKLRIKS FNIPELFVEI PETATIGSLK RTVMDVVTSI MEGGLRVGVL 420 LQGKSIQDDS KTLRQAGICH GEKLNNIDFT LECERQQDSP SGVIIAEEMD FVSADIVEPL 480 ARMKYEEPFP GTKGGGGNQQ PIKAYPNDSF AGCVHRPVEM ASQDASASLQ AIIPVAASDL 540 NALAIVPICK TRRSEFGQRR TRMPFSVGEV EALVEAVEQL GTGRWRDVKM HAFDGADHRT 600 YVDLKDKWKT LVHTASISPQ QRRGEPVPQE LLDRVLSAQA YWSQQQAKLH GKAPLPEICL 660 A*

Sequence ? help Back to Top

Protein Sequence Length: 662 aa Download sequence Send to blast

MVSQKRLGYG SRGRQIPAMP RVPNSVRGKR TTRRKKNEMC AFDLLASVAG TLLTDQDSSS  60
YVPNTSGAAT SYARNRKSVK EEYFDEILHL KNVAVKKDCG SGCVVGSGGV SALPRKGNDG  120
LAENSLTRNE DESVLKSLTV KSNMLARDSS VRCTRPCEIS RGLGIICEYG AFGVFHPGSS  180
SSAEAGQAHQ AEPKVIRSKA DGHTAALDSL FDSVDLDGRP PALVSSDSSS GVLLCSHDKE  240
HKAASLCQVE MQHTADRDDD ENSSGCTHPS TTGNEGYKPH FLGNHRIRKL LASKVRKAAR  300
NKTSGGMSSK GSKLNFCGKK IPTTRQKVQR TNFKRKKLAR GTTPFAKGML TGATGTSFRM  360
QGQNKSCGSE DYHVKLRIKS FNIPELFVEI PETATIGSLK RTVMDVVTSI MEGGLRVGVL  420
LQGKSIQDDS KTLRQAGICH GEKLNNIDFT LECERQQDSP SGVIIAEEMD FVSADIVEPL  480
ARMKYEEPFP GTKGGGGNQQ PIKAYPNDSF AGCVHRPVEM ASQDASASLQ AIIPVAASDL  540
NALAIVPICK TRRSEFGQRR TRMPFSVGEV EALVEAVEQL GTGRWRDVKM HAFDGADHRT  600
YVDLKDKWKT LVHTASISPQ QRRGEPVPQE LLDRVLSAQA YWSQQQAKLH GKAPLPEICL  660
A*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2juh_A	1e-54	550	650	5	105	Telomere binding protein TBP1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Binds the telomeric double-stranded 5'TTTAGGG-3' repeat and regulates telomere length and structure. {ECO:0000269\|PubMed:10811811, ECO:0000269\|PubMed:17586654}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Seita.5G468700.5.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012701182.1	0.0	telomere-binding protein 1 isoform X1
Refseq	XP_022682806.1	0.0	telomere-binding protein 1 isoform X1
Swissprot	Q9LL45	0.0	TBP1_ORYSJ; Telomere-binding protein 1
TrEMBL	K3XFC2	0.0	K3XFC2_SETIT; Uncharacterized protein
STRING	Si000591m	0.0	(Setaria italica)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G07540.1	8e-76	TRF-like 2

Link Out ? help Back to Top
Phytozome	Seita.5G468700.5.p
Entrez Gene	101780320

Publications ? help Back to Top
Yu EY, et al. Sequence-specific DNA recognition by the Myb-like domain of plant telomeric protein RTBP1. J. Biol. Chem., 2000. 275(31): p. 24208-14 [PMID:10811811] Hong JP, et al. Suppression of RICE TELOMERE BINDING PROTEIN 1 results in severe and gradual developmental defects accompanied by genome instability in rice. Plant Cell, 2007. 19(6): p. 1770-81 [PMID:17586654] Ko S, et al. Solution structure of the DNA binding domain of rice telomere binding protein RTBP1. Biochemistry, 2009. 48(5): p. 827-38 [PMID:19152316] Mukherjee K,Pandey DM,Vidyarthi AS In silico characterization and analysis of RTBP1 and NgTRF1 protein through MD simulation and molecular docking - A comparative study. Interdiscip Sci, 2015. [PMID:25663113] Mukherjee K,Pandey DM,Vidyarthi AS In Silico Characterization and Analysis of RTBP1 and NgTRF1 Protein Through MD Simulation and Molecular Docking: A Comparative Study. Interdiscip Sci, 2015. 7(3): p. 275-86 [PMID:26289405]