PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Seita.5G468700.2.p

Common Name

LOC101780320, SETIT_000591mg

Organism

Setaria italica

Taxonomic ID

4555

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

MYB_related

Protein Properties

Length: 637aa MW: 69276.7 Da PI: 9.7272

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Seita.5G468700.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	22.9	2e-07	537	586	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT...TTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg...kgRtlkqcksrwqky 47 r++++ E e lv+av+qlG+g+W+ + + +Rt ++k++w ++ Seita.5G468700.2.p 537 RMPFSVGEVEALVEAVEQLGTGRWRDVKMHAFdgaDHRTYVDLKDKWKTL 586 7899999******************9999899***********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54236	2.01E-7	343	419	IPR029071	Ubiquitin-related domain
PROSITE profile	PS50053	9.286	349	419	IPR000626	Ubiquitin domain
PROSITE profile	PS51294	15.733	532	591	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	3.9E-9	533	588	IPR009057	Homeodomain-like
SMART	SM00717	6.4E-7	536	589	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	8.87E-15	539	619	IPR009057	Homeodomain-like
CDD	cd11660	1.93E-16	539	588	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0032204	Biological Process	regulation of telomere maintenance
GO:0042162	Molecular Function	telomeric DNA binding
GO:0042803	Molecular Function	protein homodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 637 aa Download sequence Send to blast
MVSQKRLGYG SRGRQIPAMP RVPNSVRGKR TTRRKKNEMC AFDLLASVAG TLLTDQDSSS 60 YVPNTSGAAT SYARNRKSVK EEYFDEILHL KNVAVKKDCG SGCVVGSGGV SALPRKGNDG 120 LAENSLTRNE DESVLKSLTV KSNMLARDSS VRCTRPCEIS RGLGIICEYG AFGVFHPGSS 180 SSAEAGQAHQ AEPKVIRSKA DGHTAALDSL FDSVDLDGRP PALVEMQHTA DRDDDENSSG 240 CTHPSTTGNE GYKPHFLGNH RIRKLLASKV RKAARNKTSG GMSSKGSKLN FCGKKIPTTR 300 QKVQRTNFKR KKLARGTTPF AKGMLTGATG TSFRMQGQNK SCGSEDYHVK LRIKSFNIPE 360 LFVEIPETAT IGSLKRTVMD VVTSIMEGGL RVGVLLQGKS IQDDSKTLRQ AGICHGEKLN 420 NIDFTLECER QQDSPSGVII AEEMDFVSAD IVEPLARMKY EEPFPGTKGG GGNQQPIKAY 480 PNDSFAGCVH RPVEMASQDA SASLQAIIPV AASDLNALAI VPICKTRRSE FGQRRTRMPF 540 SVGEVEALVE AVEQLGTGRW RDVKMHAFDG ADHRTYVDLK DKWKTLVHTA SISPQQRRGE 600 PVPQELLDRV LSAQAYWSQQ QAKLHGKAPL PEICLA*

Sequence ? help Back to Top

Protein Sequence Length: 637 aa Download sequence Send to blast

MVSQKRLGYG SRGRQIPAMP RVPNSVRGKR TTRRKKNEMC AFDLLASVAG TLLTDQDSSS  60
YVPNTSGAAT SYARNRKSVK EEYFDEILHL KNVAVKKDCG SGCVVGSGGV SALPRKGNDG  120
LAENSLTRNE DESVLKSLTV KSNMLARDSS VRCTRPCEIS RGLGIICEYG AFGVFHPGSS  180
SSAEAGQAHQ AEPKVIRSKA DGHTAALDSL FDSVDLDGRP PALVEMQHTA DRDDDENSSG  240
CTHPSTTGNE GYKPHFLGNH RIRKLLASKV RKAARNKTSG GMSSKGSKLN FCGKKIPTTR  300
QKVQRTNFKR KKLARGTTPF AKGMLTGATG TSFRMQGQNK SCGSEDYHVK LRIKSFNIPE  360
LFVEIPETAT IGSLKRTVMD VVTSIMEGGL RVGVLLQGKS IQDDSKTLRQ AGICHGEKLN  420
NIDFTLECER QQDSPSGVII AEEMDFVSAD IVEPLARMKY EEPFPGTKGG GGNQQPIKAY  480
PNDSFAGCVH RPVEMASQDA SASLQAIIPV AASDLNALAI VPICKTRRSE FGQRRTRMPF  540
SVGEVEALVE AVEQLGTGRW RDVKMHAFDG ADHRTYVDLK DKWKTLVHTA SISPQQRRGE  600
PVPQELLDRV LSAQAYWSQQ QAKLHGKAPL PEICLA*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2juh_A	9e-55	525	625	5	105	Telomere binding protein TBP1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Binds the telomeric double-stranded 5'TTTAGGG-3' repeat and regulates telomere length and structure. {ECO:0000269\|PubMed:10811811, ECO:0000269\|PubMed:17586654}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Seita.5G468700.2.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022682807.1	0.0	telomere-binding protein 1 isoform X2
Swissprot	Q9LL45	0.0	TBP1_ORYSJ; Telomere-binding protein 1
TrEMBL	A0A368RGB3	0.0	A0A368RGB3_SETIT; Uncharacterized protein
STRING	Si000591m	0.0	(Setaria italica)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G07540.1	5e-76	TRF-like 2

Link Out ? help Back to Top
Phytozome	Seita.5G468700.2.p
Entrez Gene	101780320

Publications ? help Back to Top
Yu EY, et al. Sequence-specific DNA recognition by the Myb-like domain of plant telomeric protein RTBP1. J. Biol. Chem., 2000. 275(31): p. 24208-14 [PMID:10811811] Hong JP, et al. Suppression of RICE TELOMERE BINDING PROTEIN 1 results in severe and gradual developmental defects accompanied by genome instability in rice. Plant Cell, 2007. 19(6): p. 1770-81 [PMID:17586654] Ko S, et al. Solution structure of the DNA binding domain of rice telomere binding protein RTBP1. Biochemistry, 2009. 48(5): p. 827-38 [PMID:19152316] Mukherjee K,Pandey DM,Vidyarthi AS In silico characterization and analysis of RTBP1 and NgTRF1 protein through MD simulation and molecular docking - A comparative study. Interdiscip Sci, 2015. [PMID:25663113] Mukherjee K,Pandey DM,Vidyarthi AS In Silico Characterization and Analysis of RTBP1 and NgTRF1 Protein Through MD Simulation and Molecular Docking: A Comparative Study. Interdiscip Sci, 2015. 7(3): p. 275-86 [PMID:26289405]