PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Seita.5G411500.1.p
Common NameSETIT_000845mg
Organism
Setaria italica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria
Family bHLH
Protein Properties Length: 573aa    MW: 62571.7 Da    PI: 4.8713
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Seita.5G411500.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH41.81.9e-13378425355
                         HHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                 HLH   3 rahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                         ++h + Er+RR+++N+ f  L++l+P+        K++Ka+iL +++ Y+k+Lq
  Seita.5G411500.1.p 378 KNHVMSERKRREKLNEMFLVLKSLVPSiH------KVDKASILAETIAYLKELQ 425
                         5799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.1E-4918201IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.19375424IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.34E-16378429No hitNo description
PfamPF000108.3E-11379425IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.4E-17379436IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.22E-18379443IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.4E-16381430IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009957Biological Processepidermal cell fate specification
GO:0005634Cellular Componentnucleus
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 573 aa     Download sequence    Send to blast
MALPASPVQE ELQPESQLRN HLAAAVRSIN WTYALFWSIS STQPGFLTWT DGFYNGEVKT  60
RKIVNSAELT ADQLVMQRSE QLRELYEALL SGECDRRAAR PVASLSPEDL GDTELYYVVC  120
MTYAFRPGQG LPGRSFASNE RVWMWNSHLA DSKAFPRALL AKSTSIQTIV CIPLMSGVLE  180
LGTTDAVVED PSLVSRATAS FCEMQFPACS QEPSSSPSAN ETGKPADIIV FEDLDHIAME  240
AMIAGGQELG EAESLSDGSL EQITKEIDEF YSLCEEMDVQ PLEDTWIMDG SFEVPSSQQP  300
APGPATTNAA ATSSALVDGS RATSFTAWAR PESDSNEVAV PVVEEPQKLL KKAVAGGAWA  360
ANNGGGGTTR MAQESGVKNH VMSERKRREK LNEMFLVLKS LVPSIHKVDK ASILAETIAY  420
LKELQRRVQE LESSREPIIS RPSETTRATR RHDDEAVRKK VCAAGSKRKG SELGGDVERE  480
HHPRALSKDS TSNVTVTVSD KEVLVEVQCR WEELLMTRVF DAIKSLQLDV LSVQASAPDG  540
FMGLKIRAQF AGSAAVVPWM ISEALRKAIG KR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A1e-18152016192Transcription factor MYC3
4rqw_B1e-18152016192Transcription factor MYC3
4rs9_A1e-18152016192Transcription factor MYC3
4yz6_A1e-18152016192Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1383388ERKRRE
2384389RKRREK
Functional Description ? help Back to Top
Source Description
UniProtPutative transcriptional activator. Control tissue-specific synthesis of anthocyanin pigments in various parts of the maize plant.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSeita.5G411500.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004970877.10.0anthocyanin regulatory R-S protein
SwissprotP135260.0ARLC_MAIZE; Anthocyanin regulatory Lc protein
TrEMBLA0A368REN90.0A0A368REN9_SETIT; Uncharacterized protein
STRINGSi000845m0.0(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP93233109
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G09820.16e-79bHLH family protein
Publications ? help Back to Top
  1. Pattanaik S,Xie CH,Yuan L
    The interaction domains of the plant Myc-like bHLH transcription factors can regulate the transactivation strength.
    Planta, 2008. 227(3): p. 707-15
    [PMID:18075757]
  2. Huang ZA, et al.
    The upregulation of NtAN2 expression at low temperature is required for anthocyanin accumulation in juvenile leaves of Lc-transgenic tobacco (Nicotiana tabacum L.).
    J Genet Genomics, 2012. 39(3): p. 149-56
    [PMID:22464474]
  3. Ludwig SR,Habera LF,Dellaporta SL,Wessler SR
    Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region.
    Proc. Natl. Acad. Sci. U.S.A., 1989. 86(18): p. 7092-6
    [PMID:2674946]
  4. Li P, et al.
    Combined bulked segregant sequencing and traditional linkage analysis for identification of candidate gene for purple leaf sheath in maize.
    PLoS ONE, 2018. 13(1): p. e0190670
    [PMID:29304111]