PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Seita.2G342600.1.p

Common Name

LOC101753183, SETIT_030877mg

Organism

Setaria italica

Taxonomic ID

4555

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

bHLH

Protein Properties

Length: 255aa MW: 27580.6 Da PI: 6.5345

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Seita.2G342600.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	32.8	1.2e-10	93	138	4	52
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIk 52 ++ rE+ RRd++N++f eL +l + + +K++K++iL A++ + Seita.2G342600.1.p 93 TKACREKIRRDKLNERFLELGAILEPG---KTPKMDKSAILNDAIRAVG 138 7789********************9...9************8665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.44E-13	80	156	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	12.398	89	140	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.45E-8	92	145	No hit	No description
Gene3D	G3DSA:4.10.280.10	1.9E-13	92	163	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.3E-8	93	138	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.0E-9	95	146	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd14686	0.00122	155	187	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 255 aa Download sequence Send to blast
MASPEGTTWV FDCPLMDDLA VAADFAAAPA GGFFWSAAPP MQPLAVQAPM QAVAAAPAPN 60 PCVEISGSVD CDQGKEQPTN KRPRSESTAQ PSTKACREKI RRDKLNERFL ELGAILEPGK 120 TPKMDKSAIL NDAIRAVGEL RSEAQKLKDS NESLQEKIKE LKAEKNELRD EKQRLKAEKE 180 SLEQQIKFLN SRPSLVPHPP VIPASAFTTP KGPPAAGHKL MMPVIGYPGF PMWQFMPPSD 240 VDTSNDPKSC PPVA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Seita.2G342600.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004957936.1	0.0	transcription factor ILR3 isoform X2
Swissprot	Q9FH37	4e-75	ILR3_ARATH; Transcription factor ILR3
TrEMBL	K3ZW98	0.0	K3ZW98_SETIT; Uncharacterized protein
STRING	Si030877m	1e-159	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP2023	38	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	1e-72	bHLH family protein

Link Out ? help Back to Top
Phytozome	Seita.2G342600.1.p
Entrez Gene	101753183

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]