PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Seita.1G118500.1.p

Common Name

LOC101778287, SETIT_018232mg

Organism

Setaria italica

Taxonomic ID

4555

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria

Family

bHLH

Protein Properties

Length: 239aa MW: 25739.1 Da PI: 5.458

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Seita.1G118500.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	34.9	2.7e-11	72	119	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE+ RRdr+N++f eL +++ + ++ Kl+Ka iL A + + +L Seita.1G118500.1.p 72 SKACREKMRRDRLNDRFLELSSVMNPG---KQAKLDKANILSDAARMVAQL 119 6789********************9...9************999888 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	3.14E-13	62	135	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	12.309	68	119	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.32E-8	71	124	No hit	No description
Pfam	PF00010	9.1E-9	72	119	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.0E-12	73	141	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	7.6E-8	74	125	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd14686	2.89E-5	127	166	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 239 aa Download sequence Send to blast
MDGCVGGDPV EDFLLGGAGD DGDLALFCDG VPNLAGDGGL GIDGVSGDAC GFEQSNLGKR 60 ARDEPSSSGP KSKACREKMR RDRLNDRFLE LSSVMNPGKQ AKLDKANILS DAARMVAQLR 120 GEAEKLKESN EKLRENIKDL KEEKNELREE KVRLKAEKER LEQQVKAIST APTGYVPHLP 180 HPAAYHPAAF APFAPPQQAP TNKGAPIPAA FPGMAMWQWM PPTVVDTTQD PKLWPPNA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Seita.1G118500.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT040920	0.0	BT040920.1 Zea mays full-length cDNA clone ZM_BFc0152D09 mRNA, complete cds.
GenBank	EU965585	0.0	EU965585.1 Zea mays clone 287196 DNA binding protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004952164.1	1e-175	transcription factor ILR3
Swissprot	Q9FH37	5e-60	ILR3_ARATH; Transcription factor ILR3
TrEMBL	K3YVD6	1e-173	K3YVD6_SETIT; Uncharacterized protein
STRING	Si018232m	1e-174	(Setaria italica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP8173	36	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	3e-41	bHLH family protein

Link Out ? help Back to Top
Phytozome	Seita.1G118500.1.p
Entrez Gene	101778287

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]