PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676781146
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family ARF
Protein Properties Length: 822aa    MW: 91936 Da    PI: 6.3628
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676781146genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.82e-23127227198
                EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..E CS
         B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelv 93 
                f+k+lt sd++++g +++p++ ae+        ++++++  +l+ +d++ ++W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   ++++ +l+
  676781146 127 FCKTLTASDTSTHGGFSVPRRAAEKVfppldytQQPPAQ--ELIARDLHDNEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVTGDSVIFI--RNERNQLL 222
                99*****************************96555555..8************************************************..45777779 PP

                EEEE- CS
         B3  94 vkvfr 98 
                ++++ 
  676781146 223 LGIRH 227
                88876 PP
2Auxin_resp1102.5e-36253336183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 aahaa+t+s F+v+Y+Pr+s+seFv ++ k+ ka+  +++svGmRf+m fete+ss rr++Gt++g+ dld+vrWpnS+Wrs+k
   676781146 253 AAHAAATNSCFTVFYHPRSSSSEFVLPLPKYIKAVFhTRISVGMRFRMLFETEESSVRRYMGTITGIGDLDSVRWPNSHWRSVK 336
                 79*******************************986599******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.75E-48113256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.3E-40120242IPR015300DNA-binding pseudobarrel domain
CDDcd100173.30E-21126219No hitNo description
PROSITE profilePS5086312.182127229IPR003340B3 DNA binding domain
SMARTSM010192.6E-22127229IPR003340B3 DNA binding domain
PfamPF023624.5E-21127227IPR003340B3 DNA binding domain
PfamPF065075.0E-32253336IPR010525Auxin response factor
SuperFamilySSF542771.77E-7713791No hitNo description
PfamPF023098.6E-8713800IPR033389AUX/IAA domain
PROSITE profilePS5174522.6716800IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 822 aa     Download sequence    Send to blast
MNLSTSGFGH QSHEGEKKCL NSELWHACAG PLVSLPSSGS RVVYFPQGHS EQVAATTNKE  60
VEGHIPNYPS LPPQLICQLH NVTMHADVET DEVYAQMVLQ PLTQEEQKDT FVPIELGIPS  120
KQPSNYFCKT LTASDTSTHG GFSVPRRAAE KVFPPLDYTQ QPPAQELIAR DLHDNEWKFR  180
HIFRGQPKRH LLTTGWSVFV SAKRLVTGDS VIFIRNERNQ LLLGIRHATR PQTIVPSSML  240
SSDSMHIGLL AAAAHAAATN SCFTVFYHPR SSSSEFVLPL PKYIKAVFHT RISVGMRFRM  300
LFETEESSVR RYMGTITGIG DLDSVRWPNS HWRSVKVGWD ESTAGERQAR ASLWEIEPLT  360
TFPMYPSLFP LRLKRPWHPG ASSLQEKVVD GKPIFVHMEV LHAHSDADSR GDLTWLRGGA  420
GENGLLPLNY PSANVFPWMQ QRLDLSLLGT DQNQQYQAML AAGLQNIGGG DPLRQQFVQL  480
QEPNHQYLQQ SAAIHSSDLL LQQHHQASSQ QQLSRHLLQA QTQILTEHLP QQNMRQEVSN  540
QVAVQQQQPD RVWQHSDLLS PSFLKSDFTD LNNKFTSAAS PVQQQNLSLQ GSGDSSNLLN  600
FSITGQSAQS EQMPTQVWSL KHSHPETNDF SEPLSLRQAY GRASPSLEPP NTQNLSLFGV  660
DSDSGLFLPT TVPRFGTLSA DADTSSMPLT ESGFQNNLYG SMQETPELSH GVEQTKNFVK  720
VYKSGSVGRS LDISRFSSYH ELREELGKMF DIKGLLEDAF RSGWQLVFVD KEDDILLLGD  780
DPWESFVNSV WYIKILSPDD VQKMGEHGEG SNGSFPQNLA HF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1541635747388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676781146
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3527600.0AK352760.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-03-M20.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006391521.10.0auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLE4MW630.0E4MW63_EUTHA; Auxin response factor
TrEMBLV4KG440.0V4KG44_EUTSA; Auxin response factor
STRINGXP_006391521.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM13442894
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]