PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676766070
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family bHLH
Protein Properties Length: 955aa    MW: 109095 Da    PI: 8.6123
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676766070genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH27.46.1e-09800847455
                HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
        HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                +h+++Er RR++i +++  L+ l+P +    ++   Ka +L + ++Y++sLq
  676766070 800 SHSIAERARREKISERMKFLQALVPGC----NRITGKAVMLDEIINYVQSLQ 847
                8**************************....9*******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.630.105.4E-13077560IPR001128Cytochrome P450
SuperFamilySSF482641.24E-12190558IPR001128Cytochrome P450
PfamPF000671.3E-10592547IPR001128Cytochrome P450
PRINTSPR004631.3E-41120139IPR002401Cytochrome P450, E-class, group I
PRINTSPR004631.3E-41144165IPR002401Cytochrome P450, E-class, group I
PRINTSPR004631.3E-41238256IPR002401Cytochrome P450, E-class, group I
PRINTSPR004631.3E-41351368IPR002401Cytochrome P450, E-class, group I
PRINTSPR003858.8E-9362379IPR001128Cytochrome P450
PRINTSPR004631.3E-41371397IPR002401Cytochrome P450, E-class, group I
PRINTSPR004631.3E-41416434IPR002401Cytochrome P450, E-class, group I
PRINTSPR003858.8E-9417428IPR001128Cytochrome P450
PRINTSPR004631.3E-41458482IPR002401Cytochrome P450, E-class, group I
PRINTSPR004631.3E-41494504IPR002401Cytochrome P450, E-class, group I
PRINTSPR003858.8E-9495504IPR001128Cytochrome P450
PROSITE patternPS000860497506IPR017972Cytochrome P450, conserved site
PRINTSPR004631.3E-41504527IPR002401Cytochrome P450, E-class, group I
SuperFamilySSF474591.06E-15794863IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.43E-9794851No hitNo description
PROSITE profilePS5088815.307796846IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.8E-16796864IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.9E-6800847IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.6E-8802852IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0055114Biological Processoxidation-reduction process
GO:0005506Molecular Functioniron ion binding
GO:0016705Molecular Functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037Molecular Functionheme binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 955 aa     Download sequence    Send to blast
MSVAICMYHF CKRGGNGGGG VFPVTEKTNV IFPMITHGNY ATYKLKELCL TLKSSKQQLR  60
MKDIIIAVVA LPAVLLLFLL YQKTKTKWYK LPPGPKALPV IGNLHQLQKL NPQRFFYGWA  120
KKYGPIFSYK IGRKTMVVIS SAELAKELFK TQDINFADRP EHRGQEHMSY GRRDMIFHHY  180
TPYYREIRKM GMNHLFSPTR VATFKHVREE EARKMMAKIE KAAEKSEAVD ISELMLTFTN  240
TVVCRQAFGK IYNEDGEEMK RFFKIIYGTQ TVFGKIFFSD FFPYTRYILD DLTGLTAYMN  300
ECFERQDTYL QEIISERLDP NRVKPETESM IDLLMEIYRD QRFASKFTLE NVKAVVLDIV  360
VAGTDTAAAA VVWGMTYLMK YPQVMKKAQA EVRDYMREKG LTIVTEDDVK NLPYFRALVK  420
ETLRVEPVIP LGVPRCCIQD TKIAGYDIPK ETTVNVNTWA VSRDEKEWGP DPDEFRPERF  480
FEKDVDFKGT DYEFIPFGSG RRMCPGMRLG SAMLEVPYAN LLYKFNFKLL NGMKPNEINM  540
DVMTGLAMHK AEHLKLVPEK CVSFSSLISS STNRLVSIPF LNNIFSSVSA QKKLLSFRLM  600
MDKETEGTLN CLLPFGDGHE EMMISDLIGR FYDTQEISPF SENFPAQYSY PPQFGSNKVL  660
ESQQTTQESN KSSVLCPGSV SGRARTRPNS RKRKSIPTGS DKESPASSSL TASNTKVLES  720
QLLDSMYEFA LGVFLNSKVC EFLMFLSCVQ MSEEKSATVS GKRSKRNETE KSDNKDDEKP  780
TEPYKDYIHV RARRGQATDS HSIAERARRE KISERMKFLQ ALVPGCNRIT GKAVMLDEII  840
NYVQSLQRQV EFLSMKIATT NPRTEFNANV RLSAEMLQLG ESLSQSISCT EARFPSGYFA  900
IDKNIPSEGF VQAEAPAFWE NDLQSLVQMG FRDSQQQSII NCSEPTIQMK LEPEI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5ylw_A2e-76655586491Ferruginol synthase
5ym3_A2e-76655586491Ferruginol synthase
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1689694SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the metabolism of aliphatic and aromatic oximes (PubMed:12970475). Involved in the biosynthesis of both short-chain and long-chain aliphatic glucosinolates (PubMed:12509530). {ECO:0000269|PubMed:12509530, ECO:0000269|PubMed:12970475}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676766070
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009142022.10.0PREDICTED: cytochrome P450 83A1-like
RefseqXP_013744966.10.0cytochrome P450 83A1-like
RefseqXP_018514115.10.0PREDICTED: cytochrome P450 83A1-like
RefseqXP_022574144.10.0cytochrome P450 83A1-like
SwissprotP484210.0C83A1_ARATH; Cytochrome P450 83A1
TrEMBLA0A0A0N2Z40.0A0A0A0N2Z4_BRAJU; Cytochrome P450 monooxygenase CYP83A1
STRINGBra016908.1-P0.0(Brassica rapa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G23690.11e-123bHLH family protein
Publications ? help Back to Top
  1. Bak S,Feyereisen R
    The involvement of two p450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis.
    Plant Physiol., 2001. 127(1): p. 108-18
    [PMID:11553739]
  2. Ruegger M,Chapple C
    Mutations that reduce sinapoylmalate accumulation in Arabidopsis thaliana define loci with diverse roles in phenylpropanoid metabolism.
    Genetics, 2001. 159(4): p. 1741-9
    [PMID:11779811]
  3. Hemm MR,Ruegger MO,Chapple C
    The Arabidopsis ref2 mutant is defective in the gene encoding CYP83A1 and shows both phenylpropanoid and glucosinolate phenotypes.
    Plant Cell, 2003. 15(1): p. 179-94
    [PMID:12509530]
  4. Naur P, et al.
    CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis.
    Plant Physiol., 2003. 133(1): p. 63-72
    [PMID:12970475]
  5. Kliebenstein DJ,Rowe HC,Denby KJ
    Secondary metabolites influence Arabidopsis/Botrytis interactions: variation in host production and pathogen sensitivity.
    Plant J., 2005. 44(1): p. 25-36
    [PMID:16167893]
  6. Duan H,Huang MY,Palacio K,Schuler MA
    Variations in CYP74B2 (hydroperoxide lyase) gene expression differentially affect hexenal signaling in the Columbia and Landsberg erecta ecotypes of Arabidopsis.
    Plant Physiol., 2005. 139(3): p. 1529-44
    [PMID:16258015]
  7. Grubb CD,Abel S
    Glucosinolate metabolism and its control.
    Trends Plant Sci., 2006. 11(2): p. 89-100
    [PMID:16406306]
  8. Zang YX,Kim JH,Park YD,Kim DH,Hong SB
    Metabolic engineering of aliphatic glucosinolates in Chinese cabbage plants expressing Arabidopsis MAM1, CYP79F1, and CYP83A1.
    BMB Rep, 2008. 41(6): p. 472-8
    [PMID:18593532]
  9. Zhu B,Wang Z,Yang J,Zhu Z,Wang H
    Isolation and expression of glucosinolate synthesis genes CYP83A1 and CYP83B1 in Pak Choi (Brassica rapa L. ssp. chinensis var. communis (N. Tsen & S.H. Lee) Hanelt).
    Int J Mol Sci, 2012. 13(5): p. 5832-43
    [PMID:22754334]
  10. Weis C, et al.
    Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant-powdery mildew interactions.
    Mol. Plant Pathol., 2013. 14(8): p. 791-802
    [PMID:23782494]
  11. Weis C, et al.
    CYP83A1 is required for metabolic compatibility of Arabidopsis with the adapted powdery mildew fungus Erysiphe cruciferarum.
    New Phytol., 2014. 202(4): p. 1310-9
    [PMID:24602105]
  12. Liu S,Bartnikas LM,Volko SM,Ausubel FM,Tang D
    Mutation of the Glucosinolate Biosynthesis Enzyme Cytochrome P450 83A1 Monooxygenase Increases Camalexin Accumulation and Powdery Mildew Resistance.
    Front Plant Sci, 2016. 7: p. 227
    [PMID:26973671]
  13. Nintemann SJ, et al.
    Localization of the glucosinolate biosynthetic enzymes reveals distinct spatial patterns for the biosynthesis of indole and aliphatic glucosinolates.
    Physiol Plant, 2018. 163(2): p. 138-154
    [PMID:29194649]
  14. Nintemann SJ, et al.
    Unravelling Protein-Protein Interaction Networks Linked to Aliphatic and Indole Glucosinolate Biosynthetic Pathways in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 2028
    [PMID:29238354]
  15. Chapple CC
    A cDNA encoding a novel cytochrome P450-dependent monooxygenase from Arabidopsis thaliana.
    Plant Physiol., 1995. 108(2): p. 875-6
    [PMID:7610196]