PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676765190

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

Trihelix

Protein Properties

Length: 1036aa MW: 115627 Da PI: 7.8262

Description

Trihelix family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676765190	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	trihelix	73	5.2e-23	724	824	1	86
trihelix 1 rWtkqevlaLiearremeerlr....rgk...........lkkplWeevskkmrergferspkqCkekwenlnkrykkikegekkr.tsessstcpyfdq 84 +Wt+ +v++Li a+ +m+++ + +kk++W++vs++m e+gf++sp+qC++k+++lnkryk+++++ +++ +++++++ ++d+ 676765190 724 KWTDTMVRLLIMAVFYMGDEGGglglG-DqtegkkksgmlQKKGKWKSVSRAMVEKGFSVSPQQCEDKFNDLNKRYKRVNDILGRGtACRVVENQGLLDN 822 7************999999944430.134566788899******************************************559****99999 PP trihelix 85 le 86 ++ 676765190 823 MD 824 98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF53686	3.01E-99	116	468	IPR001926	Tryptophan synthase beta subunit-like PLP-dependent enzyme
TIGRFAMs	TIGR01124	2.4E-204	116	602	IPR005787	Threonine dehydratase, biosynthetic
CDD	cd01562	2.62E-142	118	422	No hit	No description
Pfam	PF00291	4.5E-80	131	416	IPR001926	Tryptophan synthase beta subunit-like PLP-dependent enzyme
PROSITE pattern	PS00165	0	154	167	IPR000634	Serine/threonine dehydratase, pyridoxal-phosphate-binding site
Gene3D	G3DSA:3.40.50.1100	5.2E-38	162	258	No hit	No description
Gene3D	G3DSA:3.40.1020.10	6.6E-45	325	506	No hit	No description
Pfam	PF00585	5.5E-20	431	520	IPR001721	ACT-like domain
CDD	cd04906	2.46E-31	440	523	No hit	No description
PROSITE profile	PS51672	11.002	441	512	IPR001721	ACT-like domain
Gene3D	G3DSA:3.40.1020.10	7.0E-31	507	606	No hit	No description
SuperFamily	SSF55021	4.58E-21	521	606	No hit	No description
Pfam	PF00585	1.5E-21	527	606	IPR001721	ACT-like domain
CDD	cd04907	3.70E-33	533	601	No hit	No description
PROSITE profile	PS51672	16.425	534	605	IPR001721	ACT-like domain
Pfam	PF13837	4.4E-20	722	850	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006520	Biological Process	cellular amino acid metabolic process
GO:0009097	Biological Process	isoleucine biosynthetic process
GO:0004794	Molecular Function	L-threonine ammonia-lyase activity
GO:0030170	Molecular Function	pyridoxal phosphate binding

Sequence ? help Back to Top
Protein Sequence Length: 1036 aa Download sequence Send to blast
MDSVRLPTAP SSLRSQMLGH PLPNRLHHIP LPPCNRHCNL RSKPAFGITR SRNHVSPMAV 60 ITGDEPSLAP TLTVDSPPPP RLKVSPNSLR YPAGYLGAVP ERTSDPENGS IAEAMEYLTN 120 ILSTKVYDIA IESPLHLAKK LSERLGVRMF LKREDLQPVF SFKLRGAYNM MAKLSGEQLA 180 KGVICSSAGN HAQGVALSAK KLGCTAVIVM PRTTPEIKWQ SVEDLGATVV LVGDSYDEAQ 240 AFAKQRAEEE GLTFIPPFDH PDIIAGQGTV GMEITRQAKG PIHAIFVPVG GGGLIAGIAA 300 YVKRVSPEVK IIGVEPADAN AMALSLHHGE RVILNQVGGF ADGVAVKEVG EETFRICKKL 360 LDGVVLVTRD AMCASIKDMF EEKRNILEPA GALSLAGAEA YCKYYGLKDV NVVVITSGAN 420 MNFDKLRIVT ELANVGRQQE AVLATLLPEK AGSFKQFCEL VGPMDITEFK YRCGSGQEAV 480 VLYSVGVHTP GELKELQKRM ESSQLRTRNL TTSDLVKDHL RYLMGGRSSV EDEVLCRFTF 540 PERPGALMNF LDSFSPRWNI SLFHYRAQGE AGANVLVGIQ VLEHEMEEFR NRAQDLGYEY 600 VLRQQDIVEE YSPKDSRLFF VFLLKKASVR KKELGMEPNV MFSGFSPRML SLEMPQNPPN 660 PVQFQHPHPM KYPYATKAKQ LSPISGGGGG DDEDRGSGSG SGCHPEDSAG TEGKRRVSQW 720 HRMKWTDTMV RLLIMAVFYM GDEGGGLGLG DQTEGKKKSG MLQKKGKWKS VSRAMVEKGF 780 SVSPQQCEDK FNDLNKRYKR VNDILGRGTA CRVVENQGLL DNMDHISPKL KDEVKKLLNS 840 KHLFFKEMCA YHNSCGHLDQ IPQPQQQPQS CFHAVESGKM ARIAESEEED ESDMVADDSD 900 SEMEDSEDEE EDTRKKRRRV EGVSAAVKRM REETTRVLED AGKSSWEKKE WMKRKALELE 960 ERKVGYEWEA VEMEKQRVKW IRYRSKKERE MDKAKLDNQR RSLETERMVL ILRRREIELT 1020 ELHLAGKRVD PSSATG

Sequence ? help Back to Top

Protein Sequence Length: 1036 aa Download sequence Send to blast

MDSVRLPTAP SSLRSQMLGH PLPNRLHHIP LPPCNRHCNL RSKPAFGITR SRNHVSPMAV  60
ITGDEPSLAP TLTVDSPPPP RLKVSPNSLR YPAGYLGAVP ERTSDPENGS IAEAMEYLTN  120
ILSTKVYDIA IESPLHLAKK LSERLGVRMF LKREDLQPVF SFKLRGAYNM MAKLSGEQLA  180
KGVICSSAGN HAQGVALSAK KLGCTAVIVM PRTTPEIKWQ SVEDLGATVV LVGDSYDEAQ  240
AFAKQRAEEE GLTFIPPFDH PDIIAGQGTV GMEITRQAKG PIHAIFVPVG GGGLIAGIAA  300
YVKRVSPEVK IIGVEPADAN AMALSLHHGE RVILNQVGGF ADGVAVKEVG EETFRICKKL  360
LDGVVLVTRD AMCASIKDMF EEKRNILEPA GALSLAGAEA YCKYYGLKDV NVVVITSGAN  420
MNFDKLRIVT ELANVGRQQE AVLATLLPEK AGSFKQFCEL VGPMDITEFK YRCGSGQEAV  480
VLYSVGVHTP GELKELQKRM ESSQLRTRNL TTSDLVKDHL RYLMGGRSSV EDEVLCRFTF  540
PERPGALMNF LDSFSPRWNI SLFHYRAQGE AGANVLVGIQ VLEHEMEEFR NRAQDLGYEY  600
VLRQQDIVEE YSPKDSRLFF VFLLKKASVR KKELGMEPNV MFSGFSPRML SLEMPQNPPN  660
PVQFQHPHPM KYPYATKAKQ LSPISGGGGG DDEDRGSGSG SGCHPEDSAG TEGKRRVSQW  720
HRMKWTDTMV RLLIMAVFYM GDEGGGLGLG DQTEGKKKSG MLQKKGKWKS VSRAMVEKGF  780
SVSPQQCEDK FNDLNKRYKR VNDILGRGTA CRVVENQGLL DNMDHISPKL KDEVKKLLNS  840
KHLFFKEMCA YHNSCGHLDQ IPQPQQQPQS CFHAVESGKM ARIAESEEED ESDMVADDSD  900
SEMEDSEDEE EDTRKKRRRV EGVSAAVKRM REETTRVLED AGKSSWEKKE WMKRKALELE  960
ERKVGYEWEA VEMEKQRVKW IRYRSKKERE MDKAKLDNQR RSLETERMVL ILRRREIELT  1020
ELHLAGKRVD PSSATG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1tdj_A	1e-130	104	599	4	498	BIOSYNTHETIC THREONINE DEAMINASE
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	915	919	KRRRV

Functional Description ? help Back to Top
Source	Description
UniProt	Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676765190

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF096281	0.0	AF096281.1 Arabidopsis thaliana threonine dehydratase/deaminase (OMR1) mRNA, complete cds.
GenBank	AY065037	0.0	AY065037.1 Arabidopsis thaliana AT3g10050/T22K18_12 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013583545.1	0.0	PREDICTED: threonine dehydratase biosynthetic, chloroplastic-like
Swissprot	Q9ZSS6	0.0	THD1_ARATH; Threonine dehydratase biosynthetic, chloroplastic
TrEMBL	A0A0D3CLJ2	0.0	A0A0D3CLJ2_BRAOL; Threonine dehydratase
TrEMBL	A0A3P6FR03	0.0	A0A3P6FR03_BRAOL; Threonine dehydratase
STRING	Bo5g137780.1	0.0	(Brassica oleracea)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10040.1	1e-168	sequence-specific DNA binding transcription factors

Publications ? help Back to Top
Mourad G,King J L-O-Methylthreonine-Resistant Mutant of Arabidopsis Defective in Isoleucine Feedback Regulation. Plant Physiol., 1995. 107(1): p. 43-52 [PMID:12228340] Jander G, et al. Ethylmethanesulfonate saturation mutagenesis in Arabidopsis to determine frequency of herbicide resistance. Plant Physiol., 2003. 131(1): p. 139-46 [PMID:12529522] Chivasa S, et al. Proteomic analysis of differentially expressed proteins in fungal elicitor-treated Arabidopsis cell cultures. J. Exp. Bot., 2006. 57(7): p. 1553-62 [PMID:16547123] Joshi V,Laubengayer KM,Schauer N,Fernie AR,Jander G Two Arabidopsis threonine aldolases are nonredundant and compete with threonine deaminase for a common substrate pool. Plant Cell, 2006. 18(12): p. 3564-75 [PMID:17172352] Less H,Galili G Principal transcriptional programs regulating plant amino acid metabolism in response to abiotic stresses. Plant Physiol., 2008. 147(1): p. 316-30 [PMID:18375600] Joshi V,Jander G Arabidopsis methionine gamma-lyase is regulated according to isoleucine biosynthesis needs but plays a subordinate role to threonine deaminase. Plant Physiol., 2009. 151(1): p. 367-78 [PMID:19571310] Yu H,Zhang F,Wang G,Liu Y,Liu D Partial deficiency of isoleucine impairs root development and alters transcript levels of the genes involved in branched-chain amino acid and glucosinolate metabolism in Arabidopsis. J. Exp. Bot., 2013. 64(2): p. 599-612 [PMID:23230023] Xing A,Last RL A Regulatory Hierarchy of the Arabidopsis Branched-Chain Amino Acid Metabolic Network. Plant Cell, 2017. 29(6): p. 1480-1499 [PMID:28522547]