PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676755044
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family bHLH
Protein Properties Length: 918aa    MW: 102497 Da    PI: 5.8437
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676755044genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH55.79e-18260306455
                HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
        HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                 hn  ErrRRdriN+++  L+el+P++      K +Ka+iL +A++Y+ksLq
  676755044 260 VHNLSERRRRDRINERMKALQELIPHC-----SKTDKASILDEAIDYLKSLQ 306
                6*************************9.....7******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474599.42E-21254315IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088819.2256305IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.69E-10259310No hitNo description
Gene3DG3DSA:4.10.280.101.9E-21260314IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.3E-15260306IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.5E-18262311IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF519051.21E-74445752IPR023753FAD/NAD(P)-binding domain
Gene3DG3DSA:3.50.50.606.5E-74446531IPR023753FAD/NAD(P)-binding domain
PRINTSPR007573.5E-7451470IPR001613Flavin amine oxidase
PfamPF015936.3E-95459887IPR002937Amine oxidase
Gene3DG3DSA:3.50.50.606.5E-74653751IPR023753FAD/NAD(P)-binding domain
SuperFamilySSF543732.75E-23734839No hitNo description
PRINTSPR007573.5E-7738757IPR001613Flavin amine oxidase
PRINTSPR007573.5E-7819838IPR001613Flavin amine oxidase
Gene3DG3DSA:3.50.50.606.5E-74848889IPR023753FAD/NAD(P)-binding domain
SuperFamilySSF519051.21E-74852887IPR023753FAD/NAD(P)-binding domain
PRINTSPR007573.5E-7870887IPR001613Flavin amine oxidase
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006598Biological Processpolyamine catabolic process
GO:0055114Biological Processoxidation-reduction process
GO:0005777Cellular Componentperoxisome
GO:0046592Molecular Functionpolyamine oxidase activity
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 918 aa     Download sequence    Send to blast
MEQLFADWNF EDNFHMSSNK RSIRPEDELV ELLWRDGQVV LQSQVRREPA AQLQTHKHDQ  60
TLRKPNSTFL ENQEIVRKPI DTVPEDQETV SWIQYPPEDV VDPFESEFSS HFFSSIDHLN  120
GPDRPEKPRT TIEETVKHET KAMAPPKFRS SVVTVGPSHC GSNHSTNDHQ VTHPPVSISD  180
RTKNVEERLD TSSGGSSGCS KETESGRSVT ISRKRKHVMD TDQESVSQSD VRLMSTDDQA  240
VGNKSSQRSG STRRSRAAEV HNLSERRRRD RINERMKALQ ELIPHCSKTD KASILDEAID  300
YLKSLQMQLQ VMWMGSGMAA AAAAAATTPM MFPGVQSSQY INQMAVQSQM HLPQFPVMNR  360
PAAQNHPGLV CQNPAVQLQM QAQNQILSEQ LARYMGGFPP MPTTAQTQTV QQPMDMLRFG  420
SSVGQQSQMS APVTTDSLPN SVERMKKRTP SVIVIGAGMA GISAARTLQD ASFQVVLLES  480
RDRIGGRVHT DYSFGFPVDL GASWLHGVCK ENPLAAVIGR LGLPLYRTSG DNSVLYDHDL  540
ESYALFDKAG NQVPQELVTK VGENFEHILE EICKVRDEQD EDMSIAQAFS IVFKRSPELS  600
SIRLIITFRL EGLAHNVLQW YLCRMEGWFA ADAETISAKC WDQEELLPGG HGLMVRGYRP  660
VINTLSKGLD IRLNHRVTKI ARRYNGVKVT TENGDTFLAD AAVIALPLGV LKSGMIEFEP  720
KLPDWKQEAI NDLGVGIENK IILNFDNVFW PNVEFLGVVA ETSYGCSYFL NLHKATSHPV  780
LVYMPAGQLA RDIEKMSDES AAKFAFSQLQ KILPDASSPI NYLVSRWGSD INSLGSYSYD  840
IVNKPHDLYE RLRVPLDNIF FAGEATSTSY PGSVHGAYST GLLAAEDCRM RVLERYGELE  900
LEIEEEAPAS VPLLISRI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4fwe_A6e-45451885358790Lysine-specific histone demethylase 1B
4fwf_A6e-45451885358790Lysine-specific histone demethylase 1B
4fwj_A6e-45451885358790Lysine-specific histone demethylase 1B
4fwj_B6e-45451885358790Lysine-specific histone demethylase 1B
4gu1_A6e-45451885346778Lysine-specific histone demethylase 1B
4gu1_B6e-45451885346778Lysine-specific histone demethylase 1B
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1264269ERRRRD
Functional Description ? help Back to Top
Source Description
UniProtFlavoenzyme involved in polyamine back-conversion (PubMed:18583528, PubMed:20532512, PubMed:21081665). Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine, spermidine and their acetyl derivatives (PubMed:18583528, PubMed:20532512, PubMed:21081665). Substrate preference is spermidine > spermine > N(1)-acetylspermidine > N(1)-acetylspermine (PubMed:18583528). Plays an important role in the regulation of polyamine intracellular concentration (Probable). Involved in the production of hydrogen peroxide during pollen tube growth (PubMed:20626657). Hydrogen peroxide triggers the opening of the hyperpolarization-activated calcium permeable channels in pollen, and thus regulates pollen tube growth (PubMed:20626657). {ECO:0000269|PubMed:18583528, ECO:0000269|PubMed:20532512, ECO:0000269|PubMed:20626657, ECO:0000269|PubMed:21081665, ECO:0000305|PubMed:18583528}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676755044
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By abscisic acid, jasmonate, salicylic acid, wounding and flagellin 22, a pathogen elicitor. {ECO:0000269|PubMed:18583528}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0856340.0AY085634.1 Arabidopsis thaliana clone 16421 mRNA, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006402729.20.0polyamine oxidase 3
SwissprotQ9LYT10.0PAO3_ARATH; Polyamine oxidase 3
TrEMBLA0A218WL790.0A0A218WL79_PUNGR; Uncharacterized protein
STRINGXP_006402729.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM34682561
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G59060.10.0phytochrome interacting factor 3-like 6
Publications ? help Back to Top
  1. Reumann S,Ma C,Lemke S,Babujee L
    AraPerox. A database of putative Arabidopsis proteins from plant peroxisomes.
    Plant Physiol., 2004. 136(1): p. 2587-608
    [PMID:15333753]
  2. Tavladoraki P, et al.
    Heterologous expression and biochemical characterization of a polyamine oxidase from Arabidopsis involved in polyamine back conversion.
    Plant Physiol., 2006. 141(4): p. 1519-32
    [PMID:16778015]
  3. Moschou PN, et al.
    Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis.
    Plant Physiol., 2008. 147(4): p. 1845-57
    [PMID:18583528]
  4. Kamada-Nobusada T,Hayashi M,Fukazawa M,Sakakibara H,Nishimura M
    A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana.
    Plant Cell Physiol., 2008. 49(9): p. 1272-82
    [PMID:18703589]
  5. Takahashi Y, et al.
    Characterization of five polyamine oxidase isoforms in Arabidopsis thaliana.
    Plant Cell Rep., 2010. 29(9): p. 955-65
    [PMID:20532512]
  6. Wu J, et al.
    Spermidine oxidase-derived H₂O₂ regulates pollen plasma membrane hyperpolarization-activated Ca(2+) -permeable channels and pollen tube growth.
    Plant J., 2010. 63(6): p. 1042-53
    [PMID:20626657]
  7. Fincato P, et al.
    Functional diversity inside the Arabidopsis polyamine oxidase gene family.
    J. Exp. Bot., 2011. 62(3): p. 1155-68
    [PMID:21081665]
  8. Fincato P, et al.
    The members of Arabidopsis thaliana PAO gene family exhibit distinct tissue- and organ-specific expression pattern during seedling growth and flower development.
    Amino Acids, 2012. 42(2-3): p. 831-41
    [PMID:21814784]
  9. Marina M, et al.
    Thermospermine catabolism increases Arabidopsis thaliana resistance to Pseudomonas viridiflava.
    J. Exp. Bot., 2013. 64(5): p. 1393-402
    [PMID:23382552]
  10. Sagor GH, et al.
    Reducing Cytoplasmic Polyamine Oxidase Activity in Arabidopsis Increases Salt and Drought Tolerance by Reducing Reactive Oxygen Species Production and Increasing Defense Gene Expression.
    Front Plant Sci, 2016. 7: p. 214
    [PMID:26973665]