PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676732644
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family MYB
Protein Properties Length: 522aa    MW: 58094.8 Da    PI: 5.9726
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676732644genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding51.22.9e-163481148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g+W+  Ed++l+d+v+q+G g+W+++ ++  + R++k+c++rw ++l
        676732644 34 KGPWSSAEDDILIDYVNQHGEGNWNAVQKHTSLFRCGKSCRLRWANHL 81
                     79******************************************9986 PP
2Myb_DNA-binding41.72.8e-1387136146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT.....TTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmg.....kgRtlkqcksrwqk 46 
                      +g++T +E+el+v++++++G++ W++ a++        gRt++++k++w++
        676732644  87 KGAFTLQEEELIVELHAKMGNR-WARMAAHRVfpsqlPGRTDNEIKNYWNT 136
                      799*******************.*******9999***************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129414.372981IPR017930Myb domain
SuperFamilySSF466892.81E-2632134IPR009057Homeodomain-like
SMARTSM007177.4E-143383IPR001005SANT/Myb domain
PfamPF002492.8E-143481IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.607.8E-233588IPR009057Homeodomain-like
CDDcd001671.03E-103681No hitNo description
PROSITE profilePS5129420.72782142IPR017930Myb domain
SMARTSM007179.8E-1386140IPR001005SANT/Myb domain
PfamPF002492.0E-1187136IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.0E-2289141IPR009057Homeodomain-like
CDDcd001671.58E-989136No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009789Biological Processpositive regulation of abscisic acid-activated signaling pathway
GO:0043068Biological Processpositive regulation of programmed cell death
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0045926Biological Processnegative regulation of growth
GO:0048235Biological Processpollen sperm cell differentiation
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 522 aa     Download sequence    Send to blast
MSYSSTESDH NESPFTDDGS DCRRSRWEAN ALKKGPWSSA EDDILIDYVN QHGEGNWNAV  60
QKHTSLFRCG KSCRLRWANH LRPNLKKGAF TLQEEELIVE LHAKMGNRWA RMAAHRVFPS  120
QLPGRTDNEI KNYWNTRIKR RQRAGLPLYP PEMHVQVLEW SQEYTKSRIL GRERSHQDFL  180
QLGSCESDVF FDSLNFVPDV VPAASDLACK LLGDGTSSPR YGNFMPSSKR LRGSESLYPG  240
CSSTLKEDIP SPEHFQNTAA QQKSSTTCSF SVPCDVDHPS YGKQHVPVMI PDSHTLTDGL  300
VPTSNPTSGE VKLELPSFQY SEATSDQWKD SASPPHSELL DPFDAYIQSP PQTGRKESDF  360
FSSYNTGLLD MLLLEANYRN NSTKNSLYKS CASPTPSPDV GEFNVSQIKS EEFGNSLKSL  420
VHSGISIPTQ HNADGIPLRQ REKERKPVLD ITRPDVWLAS SWLDHGLGIV KETGSMSDAL  480
AVLLGDDVGN DYVQMSIGAS SGVVGSCAWS NMPPVCQMTE LP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A2e-27321415107B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator of alpha-amylase expression that binds to 5'-CAACTGTC-3' motif in target gene promoter (PubMed:11743113). Positive regulator of abscisic acid (ABA) responses leading to growth arrest during seed germination (PubMed:17217461). In vegetative tissues, inhibits growth by reducing cell proliferation. Promotes the expression of aleurone-related genes (e.g. CP1, CP, GASA1, BXL1 and BXL2) in seeds. Together with MYB65 and MYB101, promotes the programmed cell death (PCD) the vacuolation of protein storage vacuoles (PSVs) in the aleurone layers during seed germination (PubMed:20699403). Binds to a GARE site (GA-response element) in the LEAFY promoter, essential for its gibberellic acid (GA)-mediated induction (PubMed:15226253). Together with MYB65, facilitates anther and tapetum development (PubMed:15722475). {ECO:0000269|PubMed:11743113, ECO:0000269|PubMed:15226253, ECO:0000269|PubMed:15722475, ECO:0000269|PubMed:17217461, ECO:0000269|PubMed:20699403}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00490DAPTransfer from AT5G06100Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap676732644
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Accumulates at the shoot apex upon the transition from short- to long-day photoperiods leading to flowering and after gibberellins (GAs) treatment (PubMed:11743113). Repressed by microRNA159 (miR159a and miR159b) in vegetative tissues (PubMed:15226253, PubMed:20699403, PubMed:17916625). Specific expression in floral organs and in the shoot apices is regulated via miR159-mediated degradation (PubMed:15722475). Repressed in germinating seeds by miR159-mediated cleavage in an abscisic acid (ABA) and ABI3-dependent manner, probably to desensitize hormone signaling during seedling stress responses (PubMed:17217461, PubMed:18305205). Slightly induced by ethylene and cytokinins (PubMed:9839469). {ECO:0000269|PubMed:11743113, ECO:0000269|PubMed:15226253, ECO:0000269|PubMed:15722475, ECO:0000269|PubMed:17217461, ECO:0000269|PubMed:17916625, ECO:0000269|PubMed:18305205, ECO:0000269|PubMed:20699403, ECO:0000269|PubMed:9839469}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006399071.10.0transcription factor MYB33 isoform X1
SwissprotQ8W1W60.0MYB33_ARATH; Transcription factor MYB33
TrEMBLV4LA660.0V4LA66_EUTSA; Uncharacterized protein
STRINGBostr.13129s0364.1.p0.0(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM38022859
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G06100.30.0myb domain protein 33
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Allen RS, et al.
    Genetic analysis reveals functional redundancy and the major target genes of the Arabidopsis miR159 family.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(41): p. 16371-6
    [PMID:17916625]
  3. Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C
    Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A.
    PLoS ONE, 2013. 8(7): p. e67987
    [PMID:23976921]
  4. Li J,Reichel M,Millar AA
    Determinants beyond both complementarity and cleavage govern microR159 efficacy in Arabidopsis.
    PLoS Genet., 2014. 10(3): p. e1004232
    [PMID:24626050]
  5. Li Y,Alonso-Peral M,Wong G,Wang MB,Millar AA
    Ubiquitous miR159 repression of MYB33/65 in Arabidopsis rosettes is robust and is not perturbed by a wide range of stresses.
    BMC Plant Biol., 2016. 16(1): p. 179
    [PMID:27542984]
  6. Liu B,De Storme N,Geelen D
    Gibberellin Induces Diploid Pollen Formation by Interfering with Meiotic Cytokinesis.
    Plant Physiol., 2017. 173(1): p. 338-353
    [PMID:27621423]
  7. Zhang F, et al.
    Phosphorylation of CBP20 Links MicroRNA to Root Growth in the Ethylene Response.
    PLoS Genet., 2016. 12(11): p. e1006437
    [PMID:27870849]
  8. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]
  9. Guo C, et al.
    Repression of miR156 by miR159 Regulates the Timing of the Juvenile-to-Adult Transition in Arabidopsis.
    Plant Cell, 2017. 29(6): p. 1293-1304
    [PMID:28536099]
  10. Xue T,Liu Z,Dai X,Xiang F
    Primary root growth in Arabidopsis thaliana is inhibited by the miR159 mediated repression of MYB33, MYB65 and MYB101.
    Plant Sci., 2017. 262: p. 182-189
    [PMID:28716415]
  11. Medina C, et al.
    Characterization of microRNAs from Arabidopsis galls highlights a role for miR159 in the plant response to the root-knot nematode Meloidogyne incognita.
    New Phytol., 2017. 216(3): p. 882-896
    [PMID:28906559]
  12. Kim MH, et al.
    Poplar MYB transcription factor PtrMYB012 and its Arabidopsis AtGAMYB orthologs are differentially repressed by the Arabidopsis miR159 family.
    Tree Physiol., 2018. 38(6): p. 801-812
    [PMID:29301041]