PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
|
Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
---|---|---|---|---|---|---|---|---|---|
TF ID | 676721990 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
|
||||||||
Family | E2F/DP | ||||||||
Protein Properties | Length: 397aa MW: 44878.2 Da PI: 8.2206 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
|
Signature Domain? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 74.1 | 1.5e-23 | 34 | 99 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l+++ +++ l+++a++L v +rRRiYDi+NVLe+++++++++kn+++wkg 676721990 34 RKQKSLGLLCTNFLALYNRHGIEMIGLDDAATKL---GV--ERRRIYDIVNVLESVGVLTRRAKNQYTWKG 99 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 79.8 | 2.5e-25 | 169 | 249 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL+lltq+f+kl+ +se++i++l+e+ak L+ + +++k+RR+YDi+NVL+++nliek ++k++++w g 676721990 169 RREKSLGLLTQNFIKLFVCSEARIISLDEAAKLLLGDahntsIMRTKVRRLYDIANVLSSMNLIEKthtldSRKPAFKWLG 249 689**************************************999************************9999*******87 PP |
Protein Features ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 6.0E-27 | 30 | 101 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 8.99E-17 | 33 | 97 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.5E-28 | 34 | 99 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.4E-20 | 35 | 99 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 2.3E-23 | 166 | 250 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.2E-32 | 169 | 249 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 3.4E-20 | 171 | 249 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 4.67E-14 | 171 | 250 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
---|---|---|---|---|---|---|
GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
---|
Protein Sequence Length: 397 aa Download sequence Send to blast |
MSDLPPEKPK MTMALSSSSS MPESSSSLHH SYSRKQKSLG LLCTNFLALY NRHGIEMIGL 60 DDAATKLGVE RRRIYDIVNV LESVGVLTRR AKNQYTWKGF SAIPAALKEL QDEGAKDTFH 120 RFYTNENVKV SDDEDDEEES SQPHSSSQTD SSKAGSLPQS SDSSKIDNRR EKSLGLLTQN 180 FIKLFVCSEA RIISLDEAAK LLLGDAHNTS IMRTKVRRLY DIANVLSSMN LIEKTHTLDS 240 RKPAFKWLGY NGEPTFTLSN DLMQAESKKR VFGTDLTNVS VKRTKTQENA TERRMKMKKH 300 AIAETSYNQS FDAHESRHGP RGYEFGPFAP ATGTYPTPPS EDNSKRAFDV ENLVSDYRPS 360 YQNQVLKDLF AHYMDAWKSW YSEVTQKNPP PDTSQHH |
3D Structure ? help Back to Top | ||||||
---|---|---|---|---|---|---|
PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 3e-40 | 33 | 241 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
---|---|---|---|
No. | Start | End | Sequence |
1 | 292 | 298 | RRMKMKK |
Functional Description ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
---|---|---|---|
Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Cis-element ? help Back to Top | |
---|---|
Source | Link |
PlantRegMap | 676721990 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | |||
GenBank | AK353197 | 0.0 | AK353197.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-26-N13. |
Annotation -- Protein ? help Back to Top | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-value | Description | ||||
Refseq | XP_006404291.1 | 0.0 | E2F transcription factor-like E2FE | ||||
Swissprot | Q8LSZ4 | 0.0 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | E4MXF0 | 0.0 | E4MXF0_EUTHA; mRNA, clone: RTFL01-26-N13 | ||||
TrEMBL | V4LPM2 | 0.0 | V4LPM2_EUTSA; Uncharacterized protein | ||||
STRING | XP_006404291.1 | 0.0 | (Eutrema salsugineum) |
Orthologous Group ? help Back to Top | |||
---|---|---|---|
Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6304 | 27 | 43 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
---|---|---|---|---|---|---|
Hit ID | E-value | Description | ||||
AT3G48160.2 | 0.0 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
---|---|---|---|
|