PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_011098539.1
Organism
Sesamum indicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum
Family E2F/DP
Protein Properties Length: 325aa    MW: 37183.2 Da    PI: 9.7136
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_011098539.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP70.61.8e-221580171
         E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                    rkeksL +l+++fl+l+++   + + l+ +a +L    v  +rRRiYDi+N+Le+++++ kk+kn+++wkg
  XP_011098539.1 15 RKEKSLSVLCTNFLRLYNRDGVESIGLDAAALQL---GV--ERRRIYDIVNILESIGVLRKKAKNQYTWKG 80
                    79*****************999************...**..****************************98 PP
2E2F_TDP72.44.8e-23136216171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     r+eksL+lltq+f+kl+ +s+ + ++l+ +a +L+ +      +++k+RR+YDi+NV+++++liek     + k+++rw+g
  XP_011098539.1 136 RREKSLGLLTQNFVKLFLCSDVELLSLDRAALALLGDsndptAMRTKVRRLYDIANVFSSMELIEKirdpqSGKPAFRWIG 216
                     689*******************************************************************99*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.1E-241381IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467853.95E-151478IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.7E-261580IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.0E-201680IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.4E-21132218IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-28136216IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.99E-11138217IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.2E-17138216IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 325 aa     Download sequence    Send to blast
MASRDSRTKD PLYSRKEKSL SVLCTNFLRL YNRDGVESIG LDAAALQLGV ERRRIYDIVN  60
ILESIGVLRK KAKNQYTWKG FGAIRGALKV LKEQGLKEEF DTYDANVSNW KACSLSSDSK  120
MKWQEKCSEP DKSEHRREKS LGLLTQNFVK LFLCSDVELL SLDRAALALL GDSNDPTAMR  180
TKVRRLYDIA NVFSSMELIE KIRDPQSGKP AFRWIGMERT SKYGSSAALD VKSSKRRVFG  240
TEISNTHEKH VLKEFVFGPF TPNVTNSEAH LNKNHRRIPD WENLSCAYQP QYRNQAISDL  300
FHHYASAWKS WYVEAEEKQQ TGPAS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A9e-32142023222Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_011098539.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011098539.10.0E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ41e-100E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A4D9B2061e-151A0A4D9B206_SALSN; Uncharacterized protein
STRINGMigut.H00175.1.p1e-150(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA25222457
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.22e-96DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]