PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_011094960.1

Organism

Sesamum indicum

Taxonomic ID

4182

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

C2H2

Protein Properties

Length: 454aa MW: 48948.9 Da PI: 6.8685

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011094960.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.2	0.00026	122	147	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 + C +C ksF ks++++Hi+ H XP_011094960.1 122 FICAapHCLKSFLKKSEFESHINEtH 147 678888****************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00162	0.00794	71	105	No hit	No description
PROSITE pattern	PS00518	0	87	96	IPR017907	Zinc finger, RING-type, conserved site
PROSITE profile	PS50157	9.058	122	148	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	124	147	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 454 aa Download sequence Send to blast
MLQIRLSKPA SETGTSTKPV HVDTVTVACP DHLVLADLPV AKGLGSASAT AVIKTVGRRS 60 RRQLGERVHF CVRCDFPIAI YGRLSPCEHA FCLDCARSDS LCYLCDERIQ KIQTIKMMEG 120 IFICAAPHCL KSFLKKSEFE SHINETHADL LYPNKEKEGN ESEAISARKP SGSDSTVQAP 180 PRPVFSPSSN SQVPDRENKT QRPQSRDQPP TRTVMQPRPV PPFSGQTPNH PSEQHPDSNQ 240 PHVFDGAASQ NRFPHQSFDP QGQGGLQQDS GLAPPQLGYA PYASGGTQQF FGPPYEMARP 300 DSTPEAGSGH GSLLGFPPGP AGPMNFPQNY PQPWNMGPAP VPLEPPLVSQ GTTDGFMSVD 360 PQGRGFFQGD YGQNVGILPS NLPPPAANMG VEQRQGGNFV DPRDGKGILA AQPLPLPPPP 420 PIPPPHLTQL QRGRSYSGDG NHDAPPGFGW QPET

Sequence ? help Back to Top

Protein Sequence Length: 454 aa Download sequence Send to blast

MLQIRLSKPA SETGTSTKPV HVDTVTVACP DHLVLADLPV AKGLGSASAT AVIKTVGRRS  60
RRQLGERVHF CVRCDFPIAI YGRLSPCEHA FCLDCARSDS LCYLCDERIQ KIQTIKMMEG  120
IFICAAPHCL KSFLKKSEFE SHINETHADL LYPNKEKEGN ESEAISARKP SGSDSTVQAP  180
PRPVFSPSSN SQVPDRENKT QRPQSRDQPP TRTVMQPRPV PPFSGQTPNH PSEQHPDSNQ  240
PHVFDGAASQ NRFPHQSFDP QGQGGLQQDS GLAPPQLGYA PYASGGTQQF FGPPYEMARP  300
DSTPEAGSGH GSLLGFPPGP AGPMNFPQNY PQPWNMGPAP VPLEPPLVSQ GTTDGFMSVD  360
PQGRGFFQGD YGQNVGILPS NLPPPAANMG VEQRQGGNFV DPRDGKGILA AQPLPLPPPP  420
PIPPPHLTQL QRGRSYSGDG NHDAPPGFGW QPET

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2mq1_A	5e-15	68	147	1	85	E3 ubiquitin-protein ligase Hakai
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable E3 ubiquitin-protein ligase which is a subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs (PubMed:28503769). Associates with MTA, MTB, FIP37 and VIR to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences (PubMed:28503769). N6-methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing (PubMed:28503769). {ECO:0000269\|PubMed:28503769}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011094960.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011094960.1	0.0	E3 ubiquitin-protein ligase Hakai
Swissprot	Q9LFC0	2e-99	HAKAI_ARATH; E3 ubiquitin-protein ligase HAKAI homolog
TrEMBL	A0A2G9I536	0.0	A0A2G9I536_9LAMI; E3 ubiquitin ligase involved in ubiquitination of E-cadherin complex
STRING	Migut.J00234.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA6404	4	5

Publications ? help Back to Top
Růžička K, et al. Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI. New Phytol., 2017. 215(1): p. 157-172 [PMID:28503769]