PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_011094221.1

Organism

Sesamum indicum

Taxonomic ID

4182

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

E2F/DP

Protein Properties

Length: 480aa MW: 53049.1 Da PI: 4.9923

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011094221.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	84.1	1.1e-26	156	221	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg XP_011094221.1 156 RYDSSLSLLTKKFITLIKHAEDGELDLNKAADTL---QV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 221 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	2.8E-28	153	223	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.2E-33	156	221	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	8.16E-17	156	219	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	2.6E-24	158	221	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	3.92E-33	235	338	No hit	No description
Pfam	PF16421	3.3E-33	237	336	IPR032198	E2F transcription factor, CC-MB domain
CDD	cd14660	2.52E-48	237	338	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 480 aa Download sequence Send to blast
MAGRGAPNRD AAATPQAAGS NGQILHHQQT PPTSIRRHLP FASMKPPFVS PDDYHRFSTP 60 ARAATSADHP PEAIVVKSPP LKRKNGYQSN EVESSEWTAS PGYSDVANSP FRTPVSAKGG 120 RTNCRSKVTK NNRSVPSTPI ANVDSPSSLT PAGSCRYDSS LSLLTKKFIT LIKHAEDGEL 180 DLNKAADTLQ VQKRRIYDIT NVLEGIGLIE KKLKNRIRWK GLDPSRPGEV DNDATLLQAE 240 IENLSLEERN LDEQIRQMQE KLRYLSEDEN NQKWLFVTED DIKILPCFQN ETLIAIKAPH 300 GTTLEVPDPD EAVDYPQRRY RIILRSTMGP IDVYLVSQFE EKFEEMNGVE QSTNFPIASS 360 SGSNVNPAVE RSSLAHSAPQ IETQTQESHE LNSVFGASQE YAGGMTRIIP SNIDNDADYW 420 LLSDADVSIT DMWKTDSGME WNDVNLLHEE LEMAAIGTPG PQTPSSSVAD LHPVANVPPR

Sequence ? help Back to Top

Protein Sequence Length: 480 aa Download sequence Send to blast

MAGRGAPNRD AAATPQAAGS NGQILHHQQT PPTSIRRHLP FASMKPPFVS PDDYHRFSTP  60
ARAATSADHP PEAIVVKSPP LKRKNGYQSN EVESSEWTAS PGYSDVANSP FRTPVSAKGG  120
RTNCRSKVTK NNRSVPSTPI ANVDSPSSLT PAGSCRYDSS LSLLTKKFIT LIKHAEDGEL  180
DLNKAADTLQ VQKRRIYDIT NVLEGIGLIE KKLKNRIRWK GLDPSRPGEV DNDATLLQAE  240
IENLSLEERN LDEQIRQMQE KLRYLSEDEN NQKWLFVTED DIKILPCFQN ETLIAIKAPH  300
GTTLEVPDPD EAVDYPQRRY RIILRSTMGP IDVYLVSQFE EKFEEMNGVE QSTNFPIASS  360
SGSNVNPAVE RSSLAHSAPQ IETQTQESHE LNSVFGASQE YAGGMTRIIP SNIDNDADYW  420
LLSDADVSIT DMWKTDSGME WNDVNLLHEE LEMAAIGTPG PQTPSSSVAD LHPVANVPPR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-24	151	224	2	76	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011094221.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011094221.1	0.0	transcription factor E2FA
Swissprot	Q9FNY0	1e-156	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A4D9AXF6	0.0	A0A4D9AXF6_SALSN; Uncharacterized protein
STRING	Migut.J00719.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-160	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]