PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_011083529.1
Organism
Sesamum indicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum
Family E2F/DP
Protein Properties Length: 449aa    MW: 49941.6 Da    PI: 8.5472
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_011083529.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.21.1e-26186251171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf+kl++++++ +++ln  a+ L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  XP_011083529.1 186 RYDSSLGLLTKKFIKLIQEAKDATLDLNRTADVL---EV--QKRRIYDITNVLEGIGLIEKTTKNHIRWKG 251
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.2E-27185252IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.99E-17186249IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.9E-34186251IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.9E-25188251IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440742.88E-24262369No hitNo description
CDDcd146604.18E-36262369No hitNo description
PfamPF164217.5E-22267366IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 449 aa     Download sequence    Send to blast
MSTSGENLDL NLSLNLPLSR MHLAAQSQSQ SPVPRLGYVR QNPFAVLPPP SSPLKLPSDK  60
FVYKNGVETP ASLSVPSKLI SDKFVMDYSN GVNTQQSRTS LPKLHLVPQN NASNELGSIA  120
RKISGDASIQ VPKQEEAVNS FSPGPVSSYM GARRSTKTKS SKHTKNVVQQ AKLEPVDNFN  180
LTGCCRYDSS LGLLTKKFIK LIQEAKDATL DLNRTADVLE VQKRRIYDIT NVLEGIGLIE  240
KTTKNHIRWK GFGSCGPKQL DDEVSRLKAE VEHLCAEDCR LDDRIRNKLE SLRELMFNQN  300
SQKNLFLTEE DIMSLPRLRN QTVIAIQAPH ASFIEVPDPD EDIVFCQKQY RLIVRSTTGP  360
IGVYLLSKDL RKSKDPSVKR AKLSDPLTWT SSRRVDEGDL SSSPSDTPTS SKTSGFQKIV  420
PLDGGIDDDY WLRSDHEVSA SDLWSTGEL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-24186253775PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_011083529.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011083529.10.0transcription factor E2FC
SwissprotQ9FV703e-89E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A2G9HCT70.0A0A2G9HCT7_9LAMI; Uncharacterized protein
STRINGMigut.C00805.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA126252022
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.22e-88E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]