PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_011077793.1

Organism

Sesamum indicum

Taxonomic ID

4182

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

E2F/DP

Protein Properties

Length: 471aa MW: 52285.8 Da PI: 4.8907

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011077793.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	84.1	1.1e-26	150	215	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg XP_011077793.1 150 RYDSSLSLLTKKFITLIKHAEDGELDLNKAADTL---QV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 215 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	3.8E-28	148	217	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	8.94E-17	150	213	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.2E-33	150	215	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	2.5E-24	152	215	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	3.92E-32	229	332	No hit	No description
Pfam	PF16421	7.9E-31	231	330	IPR032198	E2F transcription factor, CC-MB domain
CDD	cd14660	3.99E-44	231	332	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 471 aa Download sequence Send to blast
MAGLGARTGD SGATPPAAAV SGQILSKQQT PPKMIGRHLA FASMKPPFVL PDDYHRFSTP 60 PRAAADHPPE AIIVKSTPLK RRNGYENNEV ESSEWSANLG YSDMVNSPFH SSKRRKDKGP 120 LKVMKNNRSV PSILVSNVDA PSPLTPGTCR YDSSLSLLTK KFITLIKHAE DGELDLNKAA 180 DTLQVQKRRI YDITNVLEGI GLIEKKLKNR IRWKGLDPSR PGKVDNDATL LQADIENLSV 240 EERSLDERIR QMQEKLRELS EDENNHKWVF VIEDDIKNLP CFQNETLIAV KAPHGTTLEV 300 PDPDEAVDYP QRRYRIILRS TMGPIDLYLV SQFEEKFEEV NGVEQSMNFS LAPSSGSNEN 360 PEMDRASIEH SPEQIEAQSQ ETHGLNSIVG ESTGGMTKII PSNIDNDADY WLLSDGDVSI 420 TDMWKTDSGL VWDGINMLDE ELEIAALGTA RPQTPPSGIA NLTPVVNFPP R

Sequence ? help Back to Top

Protein Sequence Length: 471 aa Download sequence Send to blast

MAGLGARTGD SGATPPAAAV SGQILSKQQT PPKMIGRHLA FASMKPPFVL PDDYHRFSTP  60
PRAAADHPPE AIIVKSTPLK RRNGYENNEV ESSEWSANLG YSDMVNSPFH SSKRRKDKGP  120
LKVMKNNRSV PSILVSNVDA PSPLTPGTCR YDSSLSLLTK KFITLIKHAE DGELDLNKAA  180
DTLQVQKRRI YDITNVLEGI GLIEKKLKNR IRWKGLDPSR PGKVDNDATL LQADIENLSV  240
EERSLDERIR QMQEKLRELS EDENNHKWVF VIEDDIKNLP CFQNETLIAV KAPHGTTLEV  300
PDPDEAVDYP QRRYRIILRS TMGPIDLYLV SQFEEKFEEV NGVEQSMNFS LAPSSGSNEN  360
PEMDRASIEH SPEQIEAQSQ ETHGLNSIVG ESTGGMTKII PSNIDNDADY WLLSDGDVSI  420
TDMWKTDSGL VWDGINMLDE ELEIAALGTA RPQTPPSGIA NLTPVVNFPP R

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-24	146	218	2	76	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011077793.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011077793.1	0.0	transcription factor E2FA isoform X2
Swissprot	Q9FNY0	1e-137	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A2Z7CQD6	0.0	A0A2Z7CQD6_9LAMI; Uncharacterized protein
STRING	Migut.J00719.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-142	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]