PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sphfalx0063s0055.1.p

Organism

Sphagnum fallax

Taxonomic ID

53036

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Sphagnophytina; Sphagnopsida; Sphagnales; Sphagnaceae; Sphagnum

Family

E2F/DP

Protein Properties

Length: 386aa MW: 42242.5 Da PI: 5.0001

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sphfalx0063s0055.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.5	1.9e-27	61	126	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Sphfalx0063s0055.1.p 61 RYDSSLGLLTKKFVNLINQAEDGVLDLNKAADTL---HV--QKRRIYDITNVLEGVGLIEKKLKNRIQWKG 126 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.4E-29	57	127	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	2.0E-34	61	126	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	1.22E-17	61	124	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	1.5E-24	63	126	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	4.97E-32	140	242	No hit	No description
CDD	cd14660	2.83E-49	140	242	No hit	No description
Pfam	PF16421	2.4E-34	142	241	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 386 aa Download sequence Send to blast
MATNGWSGFS SADASPGPMH TGRRGSRSKS AKQLKNGPHT PGSSGIGSPT ASAPTPSGTC 60 RYDSSLGLLT KKFVNLINQA EDGVLDLNKA ADTLHVQKRR IYDITNVLEG VGLIEKKLKN 120 RIQWKGLGAG RPELAKGDES VLQAEVKKLH MEEQSLDERI REMREQLRTL SENEKNKQWL 180 YVTDEDIKSL SCFQNETLIA IKAPHGTTLE VPDPDEAVEY PHRRFQILLR STMGPIDVYL 240 VSRFEGKFEE MNATDPPVDT PPSAIATSQQ HESTPLMEEL GRSMSELGPL GKPDASIPSS 300 ELTNPHNDPA SGIMKIMPAE VTMDTDYWFL SDVSVGITDI WKNDTSNAMW DEMVRLNAEF 360 GIGEIGSPHP HTPPSGSTLE VEPVS*

Sequence ? help Back to Top

Protein Sequence Length: 386 aa Download sequence Send to blast

MATNGWSGFS SADASPGPMH TGRRGSRSKS AKQLKNGPHT PGSSGIGSPT ASAPTPSGTC  60
RYDSSLGLLT KKFVNLINQA EDGVLDLNKA ADTLHVQKRR IYDITNVLEG VGLIEKKLKN  120
RIQWKGLGAG RPELAKGDES VLQAEVKKLH MEEQSLDERI REMREQLRTL SENEKNKQWL  180
YVTDEDIKSL SCFQNETLIA IKAPHGTTLE VPDPDEAVEY PHRRFQILLR STMGPIDVYL  240
VSRFEGKFEE MNATDPPVDT PPSAIATSQQ HESTPLMEEL GRSMSELGPL GKPDASIPSS  300
ELTNPHNDPA SGIMKIMPAE VTMDTDYWFL SDVSVGITDI WKNDTSNAMW DEMVRLNAEF  360
GIGEIGSPHP HTPPSGSTLE VEPVS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	5e-27	56	128	1	75	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024368555.1	1e-180	transcription factor E2FA-like isoform X2
Refseq	XP_024368556.1	1e-180	transcription factor E2FA-like isoform X2
Swissprot	Q9FNY0	1e-117	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A9RQX0	1e-178	A9RQX0_PHYPA; E2F transcription factor3
STRING	PP1S22_60V6.1	1e-179	(Physcomitrella patens)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-120	E2F transcription factor 3

Link Out ? help Back to Top
Phytozome	Sphfalx0063s0055.1.p

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]