PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Sphfalx0031s0081.1.p

Organism

Sphagnum fallax

Taxonomic ID

53036

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Sphagnophytina; Sphagnopsida; Sphagnales; Sphagnaceae; Sphagnum

Family

LSD

Protein Properties

Length: 188aa MW: 19802.2 Da PI: 7.9525

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Sphfalx0031s0081.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	43.2	6.4e-14	16	40	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggCrtlL YP GA++VRCalC tV Sphfalx0031s0081.1.p 16 CGGCRTLLVYPQGASNVRCALCSTV 40 ***********************99 PP
2	zf-LSD1	46.2	7.3e-15	55	79	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggCrtlL+Y rGA+sV+C++C+tV Sphfalx0031s0081.1.p 55 CGGCRTLLMYMRGATSVQCSCCHTV 79 ************************9 PP
3	zf-LSD1	38.8	1.5e-12	93	117	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggC+ +L+Y +GA sV+CalC+ V Sphfalx0031s0081.1.p 93 CGGCGMTLMYAYGAQSVKCALCQYV 117 ***********************87 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	1.1E-15	13	43	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	9.1E-13	16	40	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	6.8E-16	52	81	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.3E-12	55	79	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	1.0E-10	90	120	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.2E-11	93	117	IPR005735	Zinc finger, LSD1-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009814	Biological Process	defense response, incompatible interaction
GO:0034052	Biological Process	positive regulation of plant-type hypersensitive response
GO:2000121	Biological Process	regulation of removal of superoxide radicals

Sequence ? help Back to Top
Protein Sequence Length: 188 aa Download sequence Send to blast
MPYQPMQGTQ QGQLICGGCR TLLVYPQGAS NVRCALCSTV TSVPPHGTEM AQLVCGGCRT 60 LLMYMRGATS VQCSCCHTVT LAIDTPPAAH INCGGCGMTL MYAYGAQSVK CALCQYVTSI 120 AIPSMQMPLL PQQQQRPLAP PQPLPPPVSV ALMQSEPQKV AVENPMTLDE SGKLVSNVAV 180 GMTTDKR*

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024389231.1	2e-86	protein LOL1-like
Swissprot	P94077	8e-53	LSD1_ARATH; Protein LSD1
TrEMBL	A0A2K1KBH6	2e-90	A0A2K1KBH6_PHYPA; Uncharacterized protein
STRING	PP1S11_54V6.1	7e-86	(Physcomitrella patens)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G32540.1	1e-53	lsd one like 1

Link Out ? help Back to Top
Phytozome	Sphfalx0031s0081.1.p

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]