PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sphfalx0027s0012.1.p
Organism
Sphagnum fallax
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Sphagnophytina; Sphagnopsida; Sphagnales; Sphagnaceae; Sphagnum
Family LSD
Protein Properties Length: 196aa    MW: 20429.7 Da    PI: 7.9696
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sphfalx0027s0012.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD139.68.9e-131943125
               zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                          CggC+tlL YP GA++VRCalC  V
  Sphfalx0027s0012.1.p 19 CGGCHTLLVYPQGASNVRCALCSSV 43
                          **********************876 PP
2zf-LSD146.17.8e-155882125
               zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                          CggCrtlL+Y rGA+sV+C++C+tV
  Sphfalx0027s0012.1.p 58 CGGCRTLLMYMRGATSVQCSCCHTV 82
                          ************************9 PP
3zf-LSD141.32.4e-1396120125
               zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                           CggC+t+L+Y +GA sV+CalC+ V
  Sphfalx0027s0012.1.p  96 CGGCGTTLMYAYGAQSVKCALCQYV 120
                           ***********************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.90.10.101.9E-41399No hitNo description
TIGRFAMsTIGR010534.2E-131646IPR005735Zinc finger, LSD1-type
SuperFamilySSF486954.46E-61841IPR011031Multihaem cytochrome
PfamPF069437.0E-121943IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010534.2E-165584IPR005735Zinc finger, LSD1-type
PfamPF069431.4E-125882IPR005735Zinc finger, LSD1-type
SuperFamilySSF486954.46E-676117IPR011031Multihaem cytochrome
TIGRFAMsTIGR010539.0E-1293123IPR005735Zinc finger, LSD1-type
PfamPF069433.4E-1296120IPR005735Zinc finger, LSD1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000303Biological Processresponse to superoxide
GO:0001666Biological Processresponse to hypoxia
GO:0002240Biological Processresponse to molecule of oomycetes origin
GO:0009626Biological Processplant-type hypersensitive response
GO:0009862Biological Processsystemic acquired resistance, salicylic acid mediated signaling pathway
GO:0010104Biological Processregulation of ethylene-activated signaling pathway
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0010602Biological Processregulation of 1-aminocyclopropane-1-carboxylate metabolic process
GO:0010618Biological Processaerenchyma formation
GO:0043069Biological Processnegative regulation of programmed cell death
Sequence ? help Back to Top
Protein Sequence    Length: 196 aa     Download sequence    Send to blast
MPYQQMQGGA GGAQGQLVCG GCHTLLVYPQ GASNVRCALC SSVTSVPTTT EMMAQLICGG  60
CRTLLMYMRG ATSVQCSCCH TVNLAMEAPP MAHINCGGCG TTLMYAYGAQ SVKCALCQYV  120
TSIAMPSMRM PLPAQQQHRP SAPQQQHPLP LPPPVAPASS AQSHTQTVVV ENPMTLDESG  180
KLVSSVAVGV TTDRR*
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024389231.11e-86protein LOL1-like
SwissprotP940776e-56LSD1_ARATH; Protein LSD1
TrEMBLA0A2K1KBH62e-88A0A2K1KBH6_PHYPA; Uncharacterized protein
STRINGPP1S11_54V6.15e-86(Physcomitrella patens)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.75e-53LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]