PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sphfalx0018s0230.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Sphagnophytina; Sphagnopsida; Sphagnales; Sphagnaceae; Sphagnum
Family E2F/DP
Protein Properties Length: 388aa    MW: 42616 Da    PI: 5.1966
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sphfalx0018s0230.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.42.1e-2763128171
               E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                           r+++sL+llt+kf++l++++e+g+++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Sphfalx0018s0230.1.p  63 RYDSSLGLLTKKFVNLIKQAEDGVLDLNKAADTL---HV--QKRRIYDITNVLEGVGLIEKKLKNRIQWKG 128
                           6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.3E-3059129IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.16E-1763126IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.4E-3563128IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.5E-2565128IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146606.77E-48139244No hitNo description
SuperFamilySSF1440742.2E-31142244No hitNo description
PfamPF164212.3E-33144243IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 388 aa     Download sequence    Send to blast
MHEMAMNGWN GFSSADASPG PTPTARRGSR SKSTKQLKNG PLTPGSSAIG SPASAPTPTS  60
TCRYDSSLGL LTKKFVNLIK QAEDGVLDLN KAADTLHVQK RRIYDITNVL EGVGLIEKKL  120
KNRIQWKGLA VAKPEAAKDD EAALQAEVEK LHMVEQSLDE RIREMRERLR TLSENEKNKQ  180
WLYVTDEDIK SLSCFQNETL IAIKAPHGTT LEVPDPDEAV EYPHRRFQIL LRSTKGPIDV  240
YLVSRFEGKF EEMNANDAPV DTPPSGMAMS HQHESTPIMQ ELGRSMSELG PLGNHDTSSP  300
SSTPSSPRND PACGIMKITP VEVTMDTDYW FLSDASVGIT DIWKNDPSNA MWDEMVRLNA  360
EFGIGEIGSP HPHTPPSGNT LEVEPVS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-2658130275PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024387507.10.0transcription factor E2FB-like isoform X4
RefseqXP_024387515.10.0transcription factor E2FB-like isoform X4
SwissprotQ9FNY01e-115E2FA_ARATH; Transcription factor E2FA
TrEMBLQ8GU410.0Q8GU41_PHYPA; Predicted protein
STRINGPP1S38_356V6.10.0(Physcomitrella patens)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.31e-107E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]