PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Sphfalx0018s0230.1.p | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Sphagnophytina; Sphagnopsida; Sphagnales; Sphagnaceae; Sphagnum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 388aa MW: 42616 Da PI: 5.1966 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.4 | 2.1e-27 | 63 | 128 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Sphfalx0018s0230.1.p 63 RYDSSLGLLTKKFVNLIKQAEDGVLDLNKAADTL---HV--QKRRIYDITNVLEGVGLIEKKLKNRIQWKG 128 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 9.3E-30 | 59 | 129 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.16E-17 | 63 | 126 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 9.4E-35 | 63 | 128 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 7.5E-25 | 65 | 128 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 6.77E-48 | 139 | 244 | No hit | No description |
SuperFamily | SSF144074 | 2.2E-31 | 142 | 244 | No hit | No description |
Pfam | PF16421 | 2.3E-33 | 144 | 243 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 388 aa Download sequence Send to blast |
MHEMAMNGWN GFSSADASPG PTPTARRGSR SKSTKQLKNG PLTPGSSAIG SPASAPTPTS 60 TCRYDSSLGL LTKKFVNLIK QAEDGVLDLN KAADTLHVQK RRIYDITNVL EGVGLIEKKL 120 KNRIQWKGLA VAKPEAAKDD EAALQAEVEK LHMVEQSLDE RIREMRERLR TLSENEKNKQ 180 WLYVTDEDIK SLSCFQNETL IAIKAPHGTT LEVPDPDEAV EYPHRRFQIL LRSTKGPIDV 240 YLVSRFEGKF EEMNANDAPV DTPPSGMAMS HQHESTPIMQ ELGRSMSELG PLGNHDTSSP 300 SSTPSSPRND PACGIMKITP VEVTMDTDYW FLSDASVGIT DIWKNDPSNA MWDEMVRLNA 360 EFGIGEIGSP HPHTPPSGNT LEVEPVS* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-26 | 58 | 130 | 2 | 75 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00661 | PBM | Transfer from Pp3c1_6880 | Download |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_024387507.1 | 0.0 | transcription factor E2FB-like isoform X4 | ||||
Refseq | XP_024387515.1 | 0.0 | transcription factor E2FB-like isoform X4 | ||||
Swissprot | Q9FNY0 | 1e-115 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | Q8GU41 | 0.0 | Q8GU41_PHYPA; Predicted protein | ||||
STRING | PP1S38_356V6.1 | 0.0 | (Physcomitrella patens) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.3 | 1e-107 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | Sphfalx0018s0230.1.p |
Publications ? help Back to Top | |||
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