PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sphfalx0008s0179.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Sphagnophytina; Sphagnopsida; Sphagnales; Sphagnaceae; Sphagnum
Family LSD
Protein Properties Length: 207aa    MW: 21677.3 Da    PI: 7.9642
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sphfalx0008s0179.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD140.64.3e-131539125
               zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                          CggCrtlL YP GA++VRCalC  V
  Sphfalx0008s0179.1.p 15 CGGCRTLLVYPQGASNVRCALCSSV 39
                          **********************876 PP

2zf-LSD143.64.8e-145579125
               zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                          C gCrtlL+Y rGA+sV+C++C+tV
  Sphfalx0008s0179.1.p 55 CAGCRTLLMYMRGATSVQCSCCHTV 79
                          ************************9 PP

3zf-LSD141.22.6e-13101125125
               zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                           CggC+t+L+Y +GA sV+CalC+ V
  Sphfalx0008s0179.1.p 101 CGGCGTTLMYAYGAQSVKCALCQYV 125
                           ***********************87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010539.9E-151242IPR005735Zinc finger, LSD1-type
PfamPF069434.0E-121539IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010531.8E-155281IPR005735Zinc finger, LSD1-type
PfamPF069431.1E-115579IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010539.8E-1298128IPR005735Zinc finger, LSD1-type
PfamPF069433.7E-12101125IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 207 aa     Download sequence    Send to blast
MPYQLMQGVQ GQLICGGCRT LLVYPQGASN VRCALCSSVT TVPPHGAAEM AQLVCAGCRT  60
LLMYMRGATS VQCSCCHTVN LAMELAPPPA AAAAAMAHIN CGGCGTTLMY AYGAQSVKCA  120
LCQYVTSIAM PPNMRIPLPP TQQQQQQLRP IVPIPPQQRL LPPPVSVASN TQSHHTQTVV  180
VENPMTLDES GKLVSNVAVG VTTDTN*
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024389231.14e-84protein LOL1-like
SwissprotP940774e-54LSD1_ARATH; Protein LSD1
TrEMBLA0A2K1KBH66e-85A0A2K1KBH6_PHYPA; Uncharacterized protein
STRINGPP1S11_54V6.12e-83(Physcomitrella patens)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.74e-48LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]