PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Sobic.008G042700.3.p | ||||||||
Common Name | Sb08g003670, SORBIDRAFT_08g003670 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum
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Family | E2F/DP | ||||||||
Protein Properties | Length: 379aa MW: 41409.8 Da PI: 4.455 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 83.6 | 1.6e-26 | 59 | 124 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kfl+ll+ ++ giv+ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg Sobic.008G042700.3.p 59 RYDSSLGLLTKKFLNLLKGAPGGIVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 124 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 5.4E-28 | 57 | 126 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 8.6E-35 | 59 | 124 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.36E-16 | 59 | 122 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.3E-23 | 61 | 124 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 3.06E-49 | 135 | 241 | No hit | No description |
SuperFamily | SSF144074 | 8.63E-34 | 136 | 241 | No hit | No description |
Pfam | PF16421 | 1.8E-33 | 140 | 239 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 379 aa Download sequence Send to blast |
MMSPGYANAG SSPVPTTPSG KGLKTSAKPK AMKGQKSCPQ TPFSVGSPGN PSTPVGGCRY 60 DSSLGLLTKK FLNLLKGAPG GIVDLNNAAE TLEVQKRRIY DITNVLEGIG LIEKKLKNNI 120 RWKGVDDSRP GEVSDDMSIL QADINALALQ ERNLDERISE MRDRLRALTE DENNQKWLYV 180 TEDDIKSLPC FQNQTLIAIK APHGTTLEVP DPDEVNGYPQ RRYRIVLRST MGPIDVYLVS 240 QFEEMSGMET PPRPTQTISM DSIENPRTPL AADCNKVTGM KLNIQEGLIL PSDAPSTSQD 300 ISGMMKLVPS ELDADTDYWL LSDNAGVSMT NMWETGPEDV EWDRIQKFNA EDFLEVGTPQ 360 QQDKPADVMD GGGPSCVS* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-23 | 48 | 125 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Sobic.008G042700.3.p |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | EU965538 | 0.0 | EU965538.1 Zea mays clone 286746 transcription factor E2F2 mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_021301272.1 | 0.0 | transcription factor E2FB isoform X1 | ||||
Swissprot | Q9FNY0 | 1e-109 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A1Z5R5C3 | 0.0 | A0A1Z5R5C3_SORBI; Uncharacterized protein | ||||
STRING | Sb08g003670.1 | 0.0 | (Sorghum bicolor) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Monocots | OGMP625 | 37 | 148 | Representative plant | OGRP1225 | 17 | 49 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-102 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | Sobic.008G042700.3.p |
Entrez Gene | 8079845 |
Publications ? help Back to Top | |||
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